How can I correct a congenital penis curvature?

Hi, i have had this problem. My penis are bent to the left and i have no pain or stress when i do the self ejaculation. But i am in a big confuse that i can marry or not? Its happen by born. What i do to get rid from it?



If your penis has been bent to the left since birth, it is not likely you have Peyronie's disease.  You probably have what we call a congenital penis curvature, or a small variation of your body that makes you different from other men.  

You ask if you should marry.  I do not know the answer to that question.  I also do not know if your penis is bent too much for you to be unable to complete the sex act. 

Keep in mind that when a woman has sufficient sexual stimulation her vaginal muscles will relax greatly, and she will produce a significant amount of lubrication.  As a result she will be able to open her vagina to allow entry of even a bent penis.  In your case, it all depends on how much you are bent and how much she can accommodate to allow entry.  That is something you will not be able to answer until you try.  

You ask how to get rid of your problem.  Many men with a congenital penis curvature have used the "Peyronie's Disease Institute Manual Penis Stretching Method" to reduce their curvature.  Although the method I developed was designed and researched to be used for Peyronies treatment, it apparently also helps me born with a bent penis. Again, you will not know if or how much this will help you until you try.  TRH

Looking for helpful Peyronies treatment information

I am seeking any information I can get that is helpful.

Thank you,



Greetings Susan,

The PDI website is huge.  Men have told me they attempted to print out the whole website, only to stop after 500 pages with still hundreds of pages to go. 

With that kind of information about Peyronies treatment readily available, what more can I offer to you?  A good place I send a lot of people is "How to Start Peyronie's Treatment".     

If you have a specific question perhaps I can answer it.   TRH

Do you suggest SSKI (potassium iodide) as a Peyronies treatment?

Do you suggest using Potassium Iodide (SSKI) as a Peyronies treatment online shows good results from using iodine for scars?


Yes, there is information online about using SSKI (potassium iodide) for treatment of Peyronie’s disease.  That information comes from the website of Jonathan V. Wright, MD of the Tohoma Clinic. He has some interesting things to say about it.  He is an intelligent and provocative author. I like Dr. Wright's work. 

However, concerning the work of PDI, there is a problem with the idea of using SSKI for PD:  Dr. Wright is the only one saying it. 

His concepts and opinions might very well be correct, and SSKI might be the best therapy imaginable for PD.  But I doubt it.  Why?  Because, from what I can determine, there has been absolutely no research or study of SSKI for treatment of PD or DC by anyone at any time.  It is all conjecture and theory, even if it is interesting and might make sense, it is still unfounded at this time.  It is a far more unfounded idea than anything you will find on the PDI website.  

The intent of PDI is not to present all Alternative Medicine therapies for your review simply because they are non-medicinal in nature.  We do not advocate Peyronie's therapies simply because they are “natural” or easy to acquire without a prescription.  Those therapies you find on the PDI website are there because of research (often a lot of it) that supports the use of that particular Alternative  Medicine therapy for PD, in spite of the contradictory research.  We take the position to only use those therapies that have satisfied an adequate percent of researchers to suggest the possibility of therapeutic efficacy.  If taken as a group, in aggressive doses and high combinations, these therapies stand a good chance of creating sufficient synergy to initiate a healing response to correct the Peyronie's plaque. 

SSKI does not fall into that description.  It has not been studied.  When it is studied and receives a positive review from several independent sources we will likely consider adding it to the lineup. 

Keep reading Dr. Wright’s articles, he has a lot of good information for all of us.  TRH


Should I continue with the same Peyronies therapy and for how long?

On 4/15/11 I suffered a trauma to my penis during sex, (no black and blue or bleeding), my girl leaned too far back while on top. I went to the urologist 2 days later experiencing pain and a lump at the base. He suggested 4 weeks of abstinence. Unfortunately that didn't work and I searched the internet for some answers. I am 47, of good health, exercise regularly, no health problems. I did the enzyme therapy,Vita-E and C, PABA and applied the Thackers formula every night. It has been 3 months now and no change in the lump at the base. I have an hour glass shape, no bend. The only change was the pain subsided within the first 2 weeks but the lump only changes size when erect it's larger and smaller while flaccid. This has been constant since the beginning. Should I continue with the same Peyronie's therapy and for how long? Please reply with any suggestions.



You ask for suggestions:

1. While abstinence might have been wise during the very acute stage of injury, it is poor Peyronie's disease treatment.  I suggest ice and anti-inflammatory measures (essential fatty acids, aspirin, etc) would have served you better.     

2. I do not know what you mean when you say you "did enzyme therapy, Vita-E and C, and PABA."   That does not tell me enough; you need to provide dosage, frequency or timing for how how you used them.  That makes a tremendous difference for the possibility of success.  Just popping pills in hopes that something works is usually not helpful and it is definitely not the way PDI suggests anyone conducts good therapy.  I cannot comment on the kind of treatment plan that you followed without knowing more about it.  I suggest you provide more information.

3.  Further, it appears that while you got your idea for using vitamin, E, vitamin C and PABA from the PDI website but you did not get your therapy products from PDI.  This is often a mistake since you have no assurance about the quality of those products or how to use them.  People who visit the PDI website for a few ideas and then experiment on their own with only partial compliance to our ideas, usually earn partial results.  I suggest you made a big mistake by deciding to experiment when you should have been actively treating yourself with known products of high quality.

4.  When you say their is no change in the lump at the base of your penis, what do you mean?  What is the current size, shape, density and surface features of that lump?  If you do not know the specific answer to those questions, I suggest you are only guessing if your lump has or has not changed.     

5.  You say since the time of your injury the lump changes size when erect compared to being flaccid, but you also say you were not black and blue as a result of the initial injury. This seems to be contradictory. Since I am not able to verify this information, I would suggest that you might be mistaken on this point. 

6.  You ask if you should continue your therapy and for how long.  You did not tell me enough about your therapy or your lump so that I can answer that question. Please provide those details.

7.  Based on the information you provided, you "did enzyme therapy, Vita-E and C, and PABA." for about two months.  That is a short time for whatever you did.  I suggest you are being too hasty judging the effectiveness of care.  This tissue is often slow to respond.

8.  I suggest you might not have Peyronie's disease at this time; you might be on your way toward it but you might not have it at this time. You notice I used the word "might" three times in that last sentence.  This is because I am unsure since your injury happened less than four months ago, and you did not present your story in a way that is typical of Peyronie's disease. My guess is that you are still in the acute stages of a soft tissue injury and that you should consider doing more to reduce the active inflammation at this time.

9.  My last suggestion is the most important:  Learn more about the correct Alternative Medicine treatment of Peyronie's disease by spending more time reading about it in the PDI website.

Good luck to you.  TRH

Does this mean I have Peyronies?

In previous questions someone asked below "how do I find my PD scar?"

In your answer you stated: "…….it is important to know your scar is not located on the surface; it is located below the surface and cannot be seen……"

I have been informed that I have Peyronie's disease, however my erections are 100% straight.  They are just less flexible and half the top surface of my penis feels very hard, because of the scar tissue.  When my penis is flaccid and erect I can easily always see the scar tissue.

Does this mean I have peyronies, also does this mean the scar tissue is just below the external skin and not on the actual erectile tissue? Is this possible? I have spoken to you previously but I am not sure if I mentioned this.



If you have been medically diagnosed with Peyronie's disease, what you say does not give me reason to doubt that diagnosis.  

After reading your entire question several times I am unsure what you mean when you say "I can easily always see the scar."   If I were to try to hide a ball under the blanket on my bed, it would still be "seen" because of the way the ball would push up and distort and wrinkle the blanket.  I would not be able to see the ball directly, only able to see the effects of the ball on the blanket that is above it.  Is this what you mean when you say you can see your PD scar?

By definition the Peyronie's plaque or scar is not located on the top surface of the skin.  It is located within the layer of tissue called the tunica albuginea that is located well below the surface of the skin, by many millimeters.     The tunica albuginea is sitting right on top of and is in contact with the actual erectile tissue, making it anatomically impossible to directly see the Peyronie's scar.  

I have communicated with many men whose PD scars are so thick and dense that they distort the skin above, and thus they can see the outline of scar that lies below.  TRH

Does DMSO cause infertility?

Does DMSO have any long term side effects i.e does it affect fertility in any way?



There are no reports or studies that connect the use of DMSO and infertility in humans whether related to Peyronie's treatment or other health problems.  There are reports of veterinary medicine using DMSO to treat infertility in horses and dogs related to fibrosis of tissues that are a part of the reproductive system.   TRH

Question about prostate surgery and Peyronie’s disease

After having an open transvesical prostatectomy on Jan. 2011 my husband, 62 years old got Peyronie's disease.  We would like to know if he can take PABA and what is the best plan treatment for him considering the fact that he suffers from essential hypertension, has two stents, smoker, and is taking daily:atenolol 100mg, disothiazide 25mg, simvastatin 40mg, acetylsalicylic acid 100mg,perphenan 4mg.

Thanks for your help.

Rachel and Benny

Greetings folks,

It is not uncommon to develop Peyronie's disease after prostate surgery.  You an read some of these ideas in my post, "Possible Peyronies Cause: Catheter and Cystoscope Trauma."

Considering your husband's medical history and the amount of drugs he is now taking, I suggest that  you tell his treating doctor you would like to try a combination Alternative Medicine nutritional approach to see if he agrees with doing a few things to increase his immune response.  Many MDs are open minded in this way, and perhaps you will get cooperation from your husband's doctor.  Personally, I see no reason to think that PABA and a few other therapies would be a problem; but first get the doctor's approval.  TRH     

What is the difference between DMSO in gel and liquid form?

Online the PDI site says your DMSO LIQUID is more effective than the GEL. I fear the topicals I use won't penetrate as deeply if i were to use the liquid? How is effectiveness different?  Thank you.


Both the gel and liquid format are effective in their own way, depending on what you want to accomplish. Read DMSO in Peyronie's Therapy.

We have determined that the DMSO liquid penetrates faster than the gel, but not only a little faster.   And we have determined that the DMSO gel penetrates deeper and carries more therapy agents with it.  For this important reason in 2009 PDI converted both the Dusa Sal DMSO (Dupuytren contracture) and PMD DMSO (Peyronie's disease) products to being made with a gel base.  It makes sense to sacrifice a little speed of penetration to gain depth and amount of therapy delivered to the tissue involved.   TRH

What are the exercises to make the penis straight?


i want to know what are the exercises to make the penis straight.  i have a curve about 40 degree in my penis.  i am not sure that i have Peyronies disease…thanks a lot


First things first.  You should have your curvature examined by a doctor and your condition diagnosed so you know what you are dealing with. That is important, so please do it.

I think you are a bit confused about your exercise question.  I am not aware of any exercise that can be done to reverse the bent penis of Peyronie's disease. 

PDI has two different educational CDs, an exercise video and a stretching video. The exercise CD is called PDI Massage and Exercise CD; it explains how to increase energy and increase blood and lymphatic flow in the lower pelvis.  The stretching CD is called  Peyronie's Disease Institute Manual Penis Stretching Method©; it explains how you can lengthen the contracted tissue of the penis and so straighten it.   TRH    

What is the success rate of PDI Peyronies treatment approach?

I am curious, what is the success rate of your Peyronies treatment approach? John from Australia

Greetings John,

You ask about PDI Peyronie's disease treatment results. All day long I send emails to men from around the world – like yourself – who do not have to report back to me, and over whom I have no control as to how, if, and when they use their various therapies.

I can only tell you this directly about the treatment results I have heard about from men over the years: I receive about 12-15 emails or telephone conversations reporting improvement in scar size, shape or density, or favorable change in penis curvature, or improvement of sexual function, for every one email or telephone call I receive complaining of no progress concerning the above. Considering that people tend to complain more than they compliment, I interpret this 12:1 ratio in a very favorable way.  But to give you percentages of natural Peyronies treatment improvement, I cannot report that to you at this time. Perhaps some time in the future when we are able to do formal research.

PDI is not yet conducting controlled studies, so I have no way of knowing how any of this is being used. And of course how these products are used determines the results that are earned. I get back bits and pieces of information from men about their treatment results. My feedback is limited in response to the large amount of information I put out to the PD community.

There is no guarantee that you or anyone else will use any of these products as I suggest that you use them. Actually, after doing this work since 2002 I find that few people start out using their Peyronie's treatment plan in the correct way.  You know how people can be. I can only hope that the suggestions I make are given fair consideration and application is made in the correct way. As a result, I do not receive with any regularity reports from men about their treatment results.

All I can tell you is that the more that a person does to knock that scar out of the tissue, the greater the synergistic effect and the greater the likelihood for success. You either understand the concept of synergy or you don’t. It is the reason that MDs have so much trouble with patients when they start putting them on more than one drug – when combined, the synergistic effect of multiple drugs begins to magnify, often causing drug reactions that most people have come to be concerned about. In the area of Alternative Medicine the results tend to be beneficial.

I notice from your records that you have only ordered Scar-X from PDI, and nothing else to treat your PD.   It is a good product we have used with success over many years. However, since you order only Scar-X you are using this product in a way it is not intended to be used.   You are a good example of what I mentioned earlier.  You are not following the suggestions of PDI and yet you will judge PDI results after not following our suggestions.   It is your decision; I can only advise you along the way and you will decide how you wish to proceed.  TRH

What can I do to make sure my penis curvature continues to straighten?

Greetings Dr. Herazy,

I've had Peyronies for close to 4 years. All I heard from those sad guys on the PD forums was that there is nothing you can do to cure PD.  But after being on your large PDI treatment plan for less than two months both my wife (a nurse) and I can tell there is a huge improvement in the curvature of my penis.  Not only is my bent straighter, I can enter her easier and we both have less pain during sex.  What can I do to make sure my Peyronies changes continue?   G.H.

Greetings G.H.

I am concerned here. Do not make any changes to your plan until you are fully versed in how to evaluate your progress via evaluation of your scar(s).  Judging your progress by positive changes in your curvature is all well and good, but it is not a reliable or accurate way to determine progress. Do not make the mistake of evaluating progress of your Peyronie's treatment plan solely on the basis of your reduced curvature. That is not the way you should do it. 

You must evaluate your treatment progress based on changes in the size, shape, density and surface features of your scar(s). Peyronie's disease is all about the scars, remember.  If you get rid of the scars your penis curvature will go away, but if your penis curvature gets straightened without change to your scar then the curvature will only come back.  

You must learn how to evaluate the scar for progress. I have a whole chapter devoted to this subject in my 1st book, “Peyronie’s Disease Handbook.” If you do not do your evaluation this way you are only guessing about progress and therefore you cannot determine correct dosage levels. Get the book if you do not have it. If you already have it, then re-read Chapter 4. 

Once you have a firm description of your PD scar then you will be able to use it as a reference point or benchmark to guide necessary changes in your treatment plan.  

Congratulations on your improvement so far, if you follow my suggestion I think you will be pleased how easily you can continue making good progress over your Peyronie's disease.   TRH

What are the best two choices to treat Peyronies?


Hi again.  Between PMD DMSO, Super CP Serum and Unique E oil what are the best two choices to treat Peyronies?   How do I go about using them?    Monty

Greetings Monty,

You are asking a question no one can answer.  You must apply these therapies to yourself to learn exactly which is most effective for you.  The PMD DMSO is always used because it will bring the other two deep into the tissue; therefore the choice is between the Super CP Serum and the Callisto oil.  Because of the low cost, most men use all three of these.

From your question it is obvious you are trying to approach Peyronies treatment from a minimal standpoint, and this is doomed for failure.  You must treat PD treatment aggressively and with a broad approach.   Also, using only external therapies (PMD DMSO, Super CP Serum and Unique E oil) only is also not a good idea; you must also use internal therapies (vitamin E, vitamin C, MSM, PABA, acetyl-L-carnitine, etc.). 

How any or all of them is actually used is provided when you receive your order.  You are given everything you need to be successful.  TRH


How can I get on the offensive after penis fracture surgery?

Hi doctor,          

How can I get on the offensive after penis fracture surgery I had two months ago. I don't acquire any scar tissue that could result in Peyronie's disease.  Is there anything you can recommend for me so soon after surgery that might help me prevent excess scar tissue from forming?  James

Greetings James, 

I suggest you consider using a PDI small plan along with Omega T in your situation to assist your tissue to heal with minimal scarring. With this approach you will supply many of the basic nutrients to your tissue  to heal your injury in this way.  At least you will have assurance that you will reduce the degree of damage if in fact some scar develops.  TRH



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What can PDI do for my 20 year old Peyronie’s disease?

hi, what can your method do for me and my 20 year old pd that started because of a sex accident?  bill

Greetings Bill,

Thanks for the question.

Since you have given me no details of your problem, I can only answer with generalities. The longest standing PD case with which I have been involved was a fellow who had it for 12 years. You see, most of the men I work with are usually in the 18 month to 3 year time range with their Peyronie's disease.  I think this is so because the average person who has dealt with PD for several years tends to just give up on himself and his situation, and assumes there is nothing out there for him.  The MDs eventually convince them to stop trying to get help because they do not have any drug for Peyronies treatment, and that is a shame.

Folks like you usually are not looking for help and answers – unfortunately.  But in the early phase of PD, a guy will really burn up the Internet wires looking for answers to his unsettling predicament. Having explained all that, it is my opinion that based on the favorable changes in the 12 year PD problem I worked with, and several others in the 3-8 year range I have worked with, your 20 year old problem stands as much a chance to improve as these others.

A long time ago I learned to never doubt the ability of the body to heal.

Many men, and myself, were able to get back all lost dimensions and eliminate any detectible scar formation, so I know it can be done. I assume you have just started to look at the large PDI website. Bear in mind what we propose is really different in the past in two important ways:
1. Synergy – grouping several therapies together at the same time.  If you are like most men who go the medical route, you probably used synthetic vitamin E for a short while and then did some POTABA or verapamil drug use later.  PDI approach is different because we advocate a combined treatment approach with many Alternative medicine therapies.
2. Quality and quantity of Alternative Medicine
most men do not appreciate the need to hit these two factors fairly hard. I can guide you in this respect to perhaps a better conclusion than you had in the past. In addition to a few vitamins, we also propose several other concurrent therapies for your PD that you have not used. These are very important to achieve the desired end result. The more you do, the stronger your synergy, the greater your odds for some success.  If you want to broaden your thinking about Peyronie's treatment with natural methods see natural Peyronie's treatment.

If you want some help to do this right, and I assume you do, send some specific questions about treatment.  PDI has a different website from anything else you will find anywhere because we have a reasonably optimistic attitude and track record with this problem, and because we actually know and care about men who have this lousy problem. I am retired now from active practice, and since overcoming and curing my own Peyronie's disease, I have pretty much devoted myself to this cause in appreciation and gratitude for the gift that was given to me.

When you are ready to do something good to help yourself, let me know.   TRH

Is the reduced penis size typical of Peyronie’s disease?

Dear Dr. H.,

I have had peyrones for about 2 years.  In that  time my penis has gotten noticeably smaller, shorter, and skinnier.   At first it looked like it did (flaccid) when I was a 10 year old kid!   And when erect, it is also smaller and bent.  Is this decrease in size a typical part of my peyronies condition?

Thank you for your response and God Bless you for all your work.

Again, thank you,



Greetings Joel,

Most men who develop Peyronie's disease begin to notice some reduction in penis size between the 6th to the 12th month.  Since everyone seems to follow a slightly different timetable for these changes this is only a guess based on information from 100s of men.  Some men experience size reduction sooner and others are later. Penis size reduction is caused by widespread thickening and contraction of the tunica and other soft tissue of the shaft that no longer can expand when the penis is filled with blood during an erection.  

This variation is also true for amount of lost erection size; some men more and some men less loss.  I have also noticed that some men lose more length than girth, and others lose more girth than length.  All of this variability is common for the way Peyronie's disease is inconsistent in so many ways. 

Loss of  penis size is a very common part of the process.  It seems that most men complain of losing 1 to 1-1/2 inches of length and about that same loss girth or circumference.   I do not recall anyone saying he has lost more than 2 inches of length, although it might only be that someone who has lost this much length is reluctant to admit to it.    TRH



If I can’t find the Peyroinie’s plaque where is DMSO gel applied?

Dr. Herazy,

My order arrived last week, and today I started the treatment.  I’m very upbeat that I made the right decision. I have carefully reviewed all the documentation and explanations that came with my order.  It is very impressive how well you prepare your customers to work with their Peyronie’s treatment products.

The one item that I’m most confused about is the PMD DMSO gel.  Exactly where is this gel applied?  My instructions say that the topical therapies should be applied over or on top of the location of the Peyronie’s plaque or scar. I do not have any scar. I don’t have a problem shaving as described but I do not have a scar either on the part to be shaved or the penis. Or, when they mention scar, do they mean the part of the penis that is abnormally hard?  Please advise.  Randy


Greetings Randy,

Actually, if you have Peyronie’s disease you do have a plaque or scar.   However, the scar is not external or superficial, it is internal and below the surface. It is located under the skin surface and within the tissue of penis called the tunica albuginea.  The scar or plaque is not visible from the surface; you cannot see it.  The closest you can come to actually seeing it is if the scar is so large and thick that it raises or elevates the penile skin above it and you can see the raised lump of tissue because of the large scar below the surface.  

In order to be successful you really want to get to the point that you know the size, shape, density, and surface quality of your scar(s). If this is a new concept to you, I suggest you get the 1st book I wrote “Peyronie’s Disease Handbook.” It will help you immensely.

Scar location is sometimes a complicated topic, especially in the case of multiple scars or plaques. You can expect to find at least one scar at the point of greatest concavity of your distortion. Again, this is a topic of such concern and importance that you really should get at least that one book so that you know what you are doing in regard to monitoring your scar. The physical change in your scar is going to guide your therapy; it will direct you to the best use of your therapy plan. to assist you with this subject, please go to Difficulty Finding the Peyronie’s Plaque.

To answer your question about where to apply the DMSO gel and related external therapies, they should be applied directly over the area of Peyronie’s plaque or scar.  You do not need to apply these external therapies to the entire shaft, unless, of course, you have a wide spread pattern of scars over most of the penis.  TRH

What can I expect from POTABA in my Peyronie’s treatment?




Greetings Bob,

In my opinion you should do a bit of online readying about POTABA. I think you will find a lot of controversy and reports of non-effectiveness about it.  From my experience there are fewer and fewer MDs using POTABA in the last few years because of high cost, limited results, and poor compliance because most men find they cannot tolerate the severe abdominal pain it causes even with the initial usage.  I am surprised your urologist did not mention this to you; I am sure he knows all about it. 

Did you ask the urologist what kind of success rate he has with this prescription?  Did you ask the urologist about what response and reactions you should expect while you are taking POTABA? I would be interested to know his response.

POTABA is one of the limited number of drugs available for prescription by an MD in the treatment of PD, although there are many MDs who do not prescribe POTABA  because they find the trouble their patients encounter while taking it does not justify the limited potential benefit.

Now, POTABA is nothing more than a simple B vitamin – PABA – that has a molecule of potassium added to it, or to say it another way, POTABA is a potassium salt of PABA.

PABA has been shown years ago in medical research to be successful in treatment of PD, but the medical profession likes to use drugs (POTABA) whenever it can, and refuses to use something as simple as a B-vitamin.  POTABA causes a host of gastric symptoms, for which reason few men complete their course of therapy with it.   PABA works just as well, and has no side-effects.  However, neither PABA or POTABA produce results as good as PABA when combined in a more aggressive therapy program as you see presented on the PDI website.

You should know this is a rather limited course of therapy.  No one can predict whether it will help you or not, you must follow if for a while to determine if it will improve the size, shape, density or surface quality of your Peyronie’s plaque.   You would be wise to get the book I wrote, “Peyronie’s Disease Handbook,” about dealing with Peyronie’s disease on a daily basis to improve your chances for recovery.

The Peyronie’s Disease Institute has offered PABA to its visitors since 2002 for treatment of Peyronie’s disease without a single report of inability to use it because of gastric problems.

Is there someting I am missing about Neprinol?

Dr. Herazy,

It is my understanding that Neprinol contains everything that the Fibrozym and Nattokinase supplements contains and is more potent, thus making it redundant to add Fibrozym to a program that already includes Neprinol.  Am I missing something?


No, some men want assurance they are not missing anything in their Peyronies treatment plan, and they intentionally use the redundancy of getting the nattokinase and serrapeptase from two different sources.

Men use Neprinol both ways – as a total substitute for the other enzyme products, or in addition to them (usually with the Neprinol being the primary enzyme source and the others being used as a minor role).  The choice is yours. When I successfully treated my own scars that is what I did – I used the Neprinol as the primary and largest supply of systemic enzymes, and then added in a few of the others per day.  

I would consider trying just the Neprinol by itself, and see how it works for you and your scar.  If that is not enough to get your scar to change favorably, then bring back the Fibrozym or Nattokinase, or Quercetin/Bromelain if you are also using it, or all of them.  You must keep experimenting to learn what makes your scar respond favorably and then continue with that.   TRH  

Does anyone know the best treatment for Peyronie’s disease?

Does anyone know the best treatment for Peyronie's disease? I want to know how do I cure myself in the fastest way I can before this problem ruins my life and pushes me over the edge.  My doctor does not seem to care at all how this problem is affecting me.  He actually told me to do nothing for six months, and then he would decide if I needed surgery. I really need to know how to get back to feeling like a normal man again.


Before I give you the best and most honest answer I can, I want you to know that I had Peyronie's disease and cured myself of it in 2002.   That is how this website got started and how all of this information was put together.  When I first developed Peyronies I felt really terrible inside just like all men do when they lose this part of their lives.  I know how rotten and scared you are feeling because I felt that way and so did hundreds of men I have worked with over the years.  Many of us, just like I did, were thinking the same terrible black thoughts you are thinking right now.  You cannot let yourself lose control of who you really are and what is really important in life.  You must not let PD win over you because you are more than just a penis, and you are stronger and more important than this problem.

Every week I get emails and phone calls from men from around the world who are making improvement with their PD scars and their curvatures.  Some get a little help, some get a tremendous amount of help, but almost everyone who works hard and follows a few simple ideas about Peyronie's treatment earns some level of improvement of this PD. 

You will not know if you can help yourself until you decide to try.  Right now you are letting PD control your thoughts and feelings, and this is not good.  You are making the mistake of allowing yourself feel like a PD victim.  Just because your MD did not spend time talking with you and did not have answers for you does not mean you cannot take care of yourself.  You can be in control of your situation if you make that decision.  It all comes down to deciding to be bigger, stronger, tougher and more determined than your PD.  Once you do that you will be in control of your feelings and you will get busy helping your body eliminate your Peyronie's plaque to the best of your ability.   TRH

Peyronie’s treatment safety issue when applying moist heat

Hi Dr. Herazy,

The use of an electrical heating pad was suggested in last month's Peyronie's Disease Institute newsletter for the moist heat therapy. I am curious as to whether or not the immense heat and warmth provided by this electrical pad would be detrimental to the testicles. The pad it hot but does not seem hot enough to scald the penis. Thank you! 



Peyronie's treatment safety should be your first concern.  To reduce possibility of excess heat being applied to penis and testicles you should:

     1. Reduce heat setting on the control of the heating pad so that the heat is not "immense" but only comfortably warm
     2. Place a small moist wash cloth between your skin and the heating pad to act as a buffer or spacer, thus reducing heat to the penis
     3. Position yourself so that your testicles are not in contact with the heating pad
     4. Place a dry wash cloth between the scrotum and heating pad to act as a buffer or space, thus reducing heat to the testicles

This suggestion for using an electric heating pad was submitted by one of the PDI Warriors and was presented in our last newsletter as an alternate way to apply moist heat to the shaft of the penis.  The original method that has been suggested by PDI is to use a hot water bottle wrapped with a moist towel and positioned to heat the shaft of the penis.  This method has the safety advantage of staying warm for 15-20 minutes before slowly losing heat.

Thank you for your observation.  TRH

How do I know if I have Peyronies disease?

Doctor,  Can you tell me how do I know for sure if I have Peyronies?  I went to my family doctor urologist last week because my penis started to bend to the right 2 months ago and it hurts.  After being in the room with me for less than 3 minutes and not even touching me, he said he was not sure if I have Peyronies so he told me to come back in 6 months to see if it gets worse.  It is driving me crazy not knowing for sure what is happening. Do I have PD or not?  Please help.  Carl


Greetings Carl, 

Sorry to learn of your problem and the difficult situation you are in. 

Unfortunately, no one can diagnose a condition as complex as Peyronie’s disease solely on the basis of the limited information you have provided.  While in your description there are certainly aspects that sound like you have PD, there is no way to say with any certainty without a direct examination.  

Typically, there are three primary criteria that must be fulfilled in order to establish a diagnosis of PD:

Arial;mso-bidi-font-family:Arial”>1.    Presence of one or more scars or nodules felt under the skin of the shaft

Arial;mso-bidi-font-family:Arial”>2.    Pain during erection

Arial;mso-bidi-font-family:Arial”>3.    Recent development of bend or significant distortion 

It is possible to make a diagnosis without one of the above, if the other two are strongly affirmative.   My advice is that if you are in doubt about the condition affecting you in this way, you should go to a urologist specializing in PD, or at least one who says he has considerable experience in this area, and ask him these same questions.   Do not allow another doctor to get away with the poor care that has been provided to you previously.

You deserve to have the peace of mind that comes from knowing exactly what it is that is affecting your health in this way.  

Good luck to you and let me know what the answer is to your question, please.  TRH

How do I find my Peyronies scar?

Hi, I'm twenty four and I think I got Peyronie's disease from an accident when I was in my early teens. It is naturally the most annoying thing I have to deal with. How do I find my Peyronies scar? Also, the medications and vitamins you are selling, how often would one need to replenish the stock?



Knowing where your scar is located – although not always easy or obvious – is essential to Peyronie's treatment.  Knowing your scar location and how to accurately describe it is not a matter of curiosity; you MUST know about the scar in as great detail as possible in order to know if you are making actual progress or not with your Alternative Medicine treatment.   If you do not know this, then you are guessing.

Before I go into this subject in some detail, I must remind you that the PD scar is best located while the penis is soft or flaccid – meaning not erect.  This will be true 99% of the time, so don’t bother to look unless you are flaccid. Also, it is important to know your scar is not located on the surface; it is located below the surface and cannot be seen.  Lastly, as a general statement the major scar you have that is causing a penile distortion will be found on the concave side of that distortion, usually at the lowest point of that concavity.

This problem of being unable to locate the PD scar is so common I wrote a blog post titled, "Can't find Peyronie's plaque or scar."  Check it out for more help.

PD “scars” or plaques are quiet variable.  Some men have an obvious scar and others could not find one if their life depended on it.   Often, when a scar is not found, but there is still pain and bending or any kind of recent penile distortion, a diagnosis of PD can still be made.  This is so, because the scar that is causing the pain or bending is either:

1. So small – it cannot be found

2. So very soft – it blends into the other tissue and cannot be detected

3. So deep – it cannot be reached or felt easily

4. So large and flat – that the edges are not easily determined, almost like trying to find the edge of a roll of plastic wrap.  When it is a large scar – as many of them are – it is something that is so close to you that you do not see it because you are looking far away and cannot see what is under your nose

5. So greatly different than what you think it is going to feel like that you miss it only because it does not meet your image of what it will be like

6.  The doctor’s lack of ability, experience or concern when he does the scar examination – that he simply misses what is actually there if he was better at this kind of thing – yes, I know, it is difficult to imagine but it is true.

Usually, when a scar is NEVER found it is because of a combination of two or more of these factors – deep and small, or soft, large and flat, or deep, soft and doctor error, and so on.  From my experience with those who have an extremely difficult time locating their scar, it seems that #4 (so large and flat) or #5 (so different than what you expect) are the reasons for failure to locate the scar.  Keep this in mind when you search your landscape trying to locate the scar. 

Ultimately, if you have PD you must begin the search with the attitude the scar is there, and it is only waiting to be found.  Do not start with a negative attitude; you want to have a sense of high anticipation that it will be found within the next few seconds – this will help keep your senses alert.  You should use as many different tactics as you can to find your scar(s) because having a good knowledge of your scar situation will help your treatment effort. 

Hint:  Try to think in terms of your scar being much larger than you have previously imagined.  Allow yourself to mentally expand the size of the scar you are looking for.  Meaning, if you were looking for a “pea” before, start looking for a “peanut” size structure or even larger.  This changes your methods and your outlook about what you can detect.  

It seems that lately I have many men reporting that their scars are as large as the length of the shaft, and some are narrow while others are wider.  Image that your scar is that large.  If you are looking for a pea-sized scar it will prevent you from easily finding something much larger like a postage stamp.     

Do not be discouraged if the scar you have is large since it does not seem that the size has much to do with difficulty or time required to eliminate it.  Larger scars can take just as long as smaller scars to treat.

Try this:  forget about finding a “scar.”  Just try to find something – anything – within the mass of erectile tissue that feels unlike the other tissue.  Find something that is unlike the rest of the tissue.  When you find it, mark its location with a marker pen or something that will stay on the tissue for a day or two.  Go back each day to that area and re-think what you are feeling.  You are trying to see if it becomes easier to make sense of it.  It could be that you have an unreasonable expectation of what a “scar” should feel like, and you are missing what is really rather obvious only because your expectation is wrong.  Really, how could you know what a PD scar feels like if you have never had to do this before?  It is a common problem.

I have worked with well over a thousand men with PD, some mild and some severe cases, some just a few months and several that were more than 10 years old.  I had a pretty bad PD problem until I cured my condition using the procedures found in the book I wrote and the same Alternative Medicine ideas as on the website.  You will not feel like a victim once you start working to improve your health and immune response against the presence of this foreign tissue.

There is no clear answer to your question about how often one would need to replenish the therapy that is being used.  Some therapies need to be resupplied every month or so, some every three months or so, and some never need to be replenish.   As a general idea about replenishing your therapy supply, the average man spends about $90-110/month replenishing his medium size PDI treatment plan.   TRH

Do you perform Peyronie’s surgery?

Hello doctor!

I read your book and I am happy that the vitamins worked for you!

My husband has Peyronie's disease the last 2 years. He saw 2 doctors and they just recommended surgery,

Do you perform Peyronie's surgery? If you don't, could you please let me know which one is the best surgeon?

Thanks so much



Yes, the PDI treatment concept worked for me and for many men who followed the concepts you see on this website.  I assume the great majority of men who have been helped to regain their freedom from Peyronie's disease were also told they needed surgery, just like your husband.  They resolved their PD problem by using Alternative Medicine treatment and did not need Peyronie's surgery.

When you go to a surgeon you will usually find that they tend to think of and recommend surgery.  Since I am not a surgeon and I philosophically prefer to first use natural conservative means before resorting to drugs or surgery, I suggest before considering any type of risky surgery that your husband should first attempt a few months using Alternative Medicine to correct his problem.   TRH   

Is there any penis surgery procedure you could recommend?


I must admit that I am very embarrassed to send this message.

I'm 52 years old with what could be a fairly long 4.5 to 5" penis, but the curvature is painful and very very frustrating for my lover and me. I keep my pubic hair shaved to give the appearance of more mass, but he is not satisfied, nor am I.

Is there any penis surgery procedure you could recommend? I have been too embarrassed to mention this to our family practitioner (female).

What first steps can I do to improve my condition?

In His name, Peter


Greetings Peter,

After reading your email a few times I am not sure if you are more concerned about the pain and distortion of your Peyronie's disease, or by your loss of penile size since you developed PD. 

We live in a strange culture in which personal self-worth and value as a human being is based on penis size.  Your penis is attached to you; you are not attached to your penis. Think about that a bit. 

There is no need for embarrassment since developing PD is not a personal character flaw or a deliberate act that suggests an imperfection of who you are as a person; it is just an unfortunate  health problem.  No one should feel embarrassed for having glaucoma or asthma, not should you feel that way because of your PD.

From my experience in communicating with many hundreds of men since 2002 about penis enlargement surgery, I hear far too many horror stories of failed surgery.  Learn to enjoy what you have and who you are, or you might be left with little to enjoy.

If you want to actually treat your real problem I suggest that your go to the PDI website to learn how to increase your ability to heal and repair your Peyronie's disease – which in turn could result in return of lost penile length and girth.   TRH

Is it adviseable to needle the penis directly?

Dr. Herazy,

I am an acupuncturist treating a patient with Peyronie's disease.  I bought your "Peyronie's Disease Handbook,"  hoping you had included specifics on the use of acupuncture, especially whether or not you think it's advisable to needle the penis directly?  I know you advise to not cause additional injury to the penis, but needling near scar tissue on other parts of the body is not contra-indicated, but actually beneficial.

What are your thoughts on this please? My patient is willing to try anything.

Greetings Doctor, 

Yes, needling a superficial scar on other parts of the body is very often beneficial, but the penis is a different part of the body. I would not needle the penis for concern of puncturing the tunica albuginea and further extending his Peyronies problem.  My concept is never to puncture the tunica in an attempt to help this problem. 

However, local treatment has always been an important part of my acupuncture practice, such as the famous Circle the Dragon technique, and that is why I advocate heavy use of the Genesen Acutouch pens to treat the PD lesion in this particular way because it will not risk injuring the patient by avoiding compromise to the tunica.

If you feel required to needle, distal points are always advisable. I do not treat a lot based on Five Elements theory, but I believe you would likely benefit your patient by evaluating for an Excess Wood situation.  Bear in mind that the “Peyronie’s “scar” is not a scar in the traditional sense of being a superficially located skin lesion; it is below the subdermis and within the tunica so the standard methods of needling a scar – that I have done daily for over 35 years – does not apply to PD.  At least, that is how I understand it based on my concept and methodology in guiding Peyronie's treatment.

If you feel obligated to needle, distal points are always advisable such as SP3, SP6, K3, GB34, the master points of the Conception Vessel, Sedation points for the Wood element and and Stimulation points for the Fire element. as well as appropriate Eight Extraordinary Meridian points (Du Mai, Chong mai, Yin Wei mai, etc.)    TRH  


Am I cheating on my wife?

Greetings Dr Herazy, 

I was wondering.  Since my penis has been bent over 70 degrees for the last few years of my Peyronies, my wife and I are not having any intercourse.  During this time, every now I have been masturbating without my wife's knowledge.  Am I cheating on her? 


Greetings Paul,

No, you are just keeping the pilot light burning for her benefit later. 

You owe it to her to be less shy and more creative.  You know, you are not the only one that needs sex every now and then. She is probably feeling lonely and neglected.  I encourage you to include her in your private efforts and maybe you two can share some favors. There is a world of sexual adventure and satisfaction for a married couple outside of traditional intercourse.  I go into all these areas in my book "Peyronie's Disease and Sex."   Don't be so selfish.  

The important goal is to get over your Peyronie's disease so you no longer have this limitation.  Stay focused on your PD treatment, please. TRH  

How do I get the DMSO gel to stay on?

How do I get the DMSO gel to stay on?  It's so viscous it won't spread out on it's own.

Tom. U.

Greetings Tom,

Never been asked that question before. My guess is that because DMSO “freezes” somewhere around 62 (?) degrees Fahrenheit, that this might be your problem. If the place where you are keeping it is rather cool, it might simply be close to turning to a solid.

I suggest you simply place it in a container of warm – not hot – water to allow it to come to its normal liquid state. The DMSO gel should have the consistency of  liquid hair shampoo. Be sure that the DMSO is the last thing you apply to the area if you are also using Super CP Serum and Unique-E oil to the shaft.   TRH

Why is it you do not offer any guarantee?

I have Peyronies disease now since I discovered I was getting a bent penis in November last year. My doctor prescribed potaba but it has done nothing in almost 4 months of treatment and in fact it seems to have got worse. I also am taking vitamin e and c that I got from the health food store but again it has done nothing.

My penis is bending sideways and upwards and seems to have an indent underneath at the head of the penis. All very upsetting psychologically also.

I found your web site and read your treatment options.  Why is it you do not offer any guarantee of your treatment?


Greetings Alex,

You must be using the correct vitamin products in the correct way to gain a positive response.  Just because you got your vitamin E and C from the health food store does not mean that they were good products.  It is estimated that over 25% of vitamin and herbal supplements sold on the open market do not contain what the label says. Many have inferior grade synthetic products.  Not all vitamin E products are created equal, and many are not what they say they are. If you are using an inferior product (without knowing it) you will not get good results. That is why I strongly encourage any one who wants to treat his Peyronie's disease with Alternative Medicine products to get them from PDI for a few reasons:

  • High product quality – these are the same products I used when I successfully treated my own PD problem
  • Great prices and discounts
  • Fresh products since PDI is the largest buyer of several of the products we sell
  • Proven effectiveness – results since 2002
  • Consultation about your treatment – I cannot discuss your treatment, or answer your questions, if I do not have experience or confidence in outside therapy products

Using only vitamin E and vitamin C is a very limited and poorly designed Peyronie's treatment idea.  I have never heard of anyone getting results with that kind of plan.   These two vitamins are great products and serve an important part in many of the plans we use, but they cannot do the total job to eliminate the PD scar. I would never suggest to anyone to try using only only vitamin E and vitamin C as you did.   

Most men who go about using their own ideas and get their own products like you are doing make very little progress with their Peyronie's disease problem.  This is a complicated and difficult problem.  You will have to admit you are guessing at a lot of what you have done and your are experimenting on yourself at a time when you should be actively treating yourself.  On the PDI website we provide a tremendous amount of free services and information like this constantly updated Q&A section and a Peyronie's treatment forum, along with private emails to men from around the world. We make these resources available to men to support their effort to correct their own PD.  If you work with the PDI system of treatment I can assist you when ideas, information and suggestions based on my experience; you will not be working alone.

You ask about a guarantee.

Who do you know in the healthcare field who offers a guarantee for any procedure or therapy? Aspirins do not come with a guarantee.  Jock itch spray does not come with a guarantee.  Toothpaste does not come with a guarantee.  Foot supports do not come with a guarantee.  Surgery does not come with a guarantee.  No one in healthcare offers a guarantee because of the complexity and difficulty of what we are attempting to do.  Everything in health care is completely unpredictable.   When you go to your dentist and he puts some Novocain in your gum, during your dental procedure he will ask you frequently if your mouth is still numb, right?  He has to ask you if your mouth is numb because he cannot guarantee the Novocain will work for you, or if he got enough in your tissue, or if he put it in the right location, or if it is not wearing off sooner than it should.  Nothing in health care can be guaranteed. 

Only people who are trying to fool you offer a guarantee for their unscrupulous products.  I see many international companies ( like in Pakistan, India, Romania) who try to sell secret herbal products and guarantee results in 30-60 days.  I hear frequently from men who bought those pills, got no results, and got no response from those companies when they tried to get their guaranteed refund.  

Be very suspicious when you see some treatment offered with a guarantee especially for Peyronie's disease.

If you are interested in trying to help your body heal the Peyronie's scars, please let me know.   TRH 

Can I use the PDI manual penis stretching technique to cure my curvature?

Hi  Doctor,

I have a normally bent penis with a downward curve.  I have it from when I was a child.  There is no pain, just normal curve 30 degree.   Can I use the  PDI manual stretching CD to cure my curvature ??



Many men have a curved penis from birth; it is part of what makes you a unique person.

I have had reports from men who have used the manual penis stretching technique to safely and permanently change their normally curved penis.  You can read more about the CD that explains in detail how to use this special technique at Peyronie's Disease Institute Manual Penis Stretching Method©

Keep in mind that your bent penis is a normal condition for you, even though it is 30 degrees.  Your improvement might be less than complete straightening, or it could be complete, there is no way to know ahead of time until you try it.   Please let me know how it goes for you.  TRH 

What is my opinion of prescription drug injection?

What is the Dr's opinion on using the prescription Edex injected with a syringe? 

Bryant from Ohio


Greetings Bryant, 

You ask for my opinion about Edex injections.  I will not comment on the drug, because that is the decision of your treating doctor.  But I will make a few observations about injections in general and how they could further injure the tunica albuginea.

Anytime you inject ANYTHING – even sterile water – into the penis and directly or indirectly contact the delicate tunica albuginea, you are taking a serious risk of making your Peyronie's disease worse. This could either occur just from the simple act of piercing the tissue of the tunica albuginea, or the placement of a concentrated chemical that is foreign to that tissue, or both.

I have communicated with many, many men whose Peyronie's disease started or was made worse from penile injections of a variety of substances.

If your problem is PD, why are you taking an ED medication? Some MDs prescribe Viagra, Edex, etc to their PD patients in the belief that this increases the local circulation which in turn is beneficial to PD.

What if you could take a drug that would enable you to lift a ton of weight above your head and keep it there for an hour? Nice trick, very impressive, but your body is not built to take that kind of pressure. It would cause great damage to internal organs, your spine, your blood vessels, all major joints, etc. Simply put, “It just ain’t natural.” Same with Viagra, Levitra or Cialis. The increased pressure created by these medications can be very damaging to the delicate tunica albuginea, and can result in or worsen a case of PD. What would happen to your car tires if you happened to over-inflate them with 100 pounds of air pressure, even though they were built to take just 40 pounds of pressure. You would be running the risk of damage to the internal structure of tire, wouldn’t you? Of course.

The same thing can happen if the penis is over-inflated and then given a “rough ride.” This is where the problems start, and this is what I wanted to bring to your attention. It is very likely that the MDs who prescribe these medications to men with PD will not agree with this thinking. MDs tend to favor a chemical “fix” even if it is temporary, so you would tend to expect a prejudice from an MD to use drugs to solve most problems.

A penis that is predisposed to PD in the first place cannot tolerate the kind of stress that these erections drugs create.  If you think independently and logically about what happens when these drugs are used, you should have no trouble understanding how this could work against you.  That is just the way I see it and I feel compelled to share this rationale with you. Use of Viagra and other related meds like it could easily be worsening the very problem you are attempting to heal. Something to think about.  TRH

How do I help my husband deal with his reduced interest in sex since he developed Peyronie’s disease?


My husband was diagnosed with Peyronie’s disease a little more than two years ago but is not doing anything about it.  His doctor told him there is nothing to do for his condition except surgery, so he has just shut down.  He will not talk to me about his severe curvature and he refuses to discuss how we are going to continue like this.  In fact, over the last few months he is talking to me less and less.  We have not had intimate relations since all this started.

Of course I am worried about his physical condition, but I also see him becoming more isolated and quick to get angry and this makes me worried for him.  He is a good man and we had a great relationship before this happened. 

I see that your attitude and approach is so much different about this problem that I hope you can help us.  How do I help my husband deal with his lack of interest in sexual activity since he first developed Peyronie’s disease?


P.S.  Thanks for helping others.


Greetings Harriet,

Sorry to learn that your husband has withdrawn from his problem, but this is actually a very common situation.  Many men respond this way when they develop Peyronie’s disease.  I know so because I receive emails all the time from worried wives that report the same thing you are going through. Peyronie’s disease can be very stressful and confusing for the man who gets it, but also for his wife who desperately wants to help and does not know how. It can hurt a lot.

This subject is broad and deep.  In fact, because it is so common and important in PD treatment I devoted a considerable portion of the 2nd book I wrote to this area of the relationship of any couple dealing with PD.  I suggest you go to the PDI website and order the book, “Peyronie’s Disease and Sex” to learn what you can do to help your husband, because there is actually a lot you can do.   I know this book will help you to understand what is going on inside him, and what you can do now to bridge the gap between you.

From considerable past experience I can tell you that his lack of communication with you, and his withdrawal from sexual contact, are all related to fear and shame.   Become more knowledgeable about Peyronie’s disease; learn some of the more technical terms and concepts; learn about natural PD treatment; memorize just a few facts about PD.  The very next time you are given a natural and appropriate opportunity to mention something about PD, include some of this new technical information in your conversation.  Talk about Peyronie’s disease and the treatment ideas you learned on the PDI website.  Do not talk about or mention what is going on with him.  Do not make it personal at this time; make the conversational general so he is not made to feel any more uncomfortable than necessary,   Just the fact that you suddenly know these things will tell him that you are on his side, and that you now know a few things that might help him.  Slowly draw him out this way. If he asks, show him the PDI website and show him how to explore it.

If you can make him aware that there is actually a reasonable and effective approach to Peyronie’s treatment that his MD did not know about, you can give your husband a a reason to get excited about overcoming his problem.  This approach has helped save other marriages and could help you also.

Let me know if you have any specific questions I can assist you with.    TRH

What is the daily dose recommended for Neprinol?

What is the daily dose recommended for Neprinol? Thank you.

Bill C.

Greetings Bill C.,

There are several things to say about dosage in general for Peyronie treatment, that applies to Neprinol dosage in particular

1.  The starting dosage for any therapy is often the one that is listed on the label for that product.  This standard starting point is used to see if the dosage recommended by the product manufacturer can bring about a favorable change in the size, shape, density and surface features of your scar.  Often it cannot.

2.  The ongoing treatment dosage that eventually proves to reduce the original size and shape of the scar, or soften the density, or alter the surface features of a Peyronies plaque will very often be higher than what is suggested on the label of each product. 

3.  No matter which therapy product you use, it must be taken in a safe and reasonable dosage.  All of this information is available to you in the treatment section of the PDI website.  Please read that information and adhere to it.  

4.  Dosage for any ONE therapy product that is actually going to help your Peyronie's disease is not easy to determine because you will be taking MANY therapy products at the same time.  You are juggling many balls at once and this requires some patience and the ability to keep good notes about what you are doing. 

Of course, if you are taking five different internal therapies (vitamin E, vitamin C, Neprinol, Acetyl-L-carnitine and PABA) each one must be individually determined.  An important part of your therapy plan are the external therapies you are using (Genesen Acutouch pens, gentle manual stretching, DMSO, etc.) While you do all the internal and external therapies that make up your total therapy plan you must monitor the size, shape, density and surface quality of your scar(s) to note at what dosage level changes begin in the scar material.  It is as simple – and difficult – as that.

5. No clear and specific treatment dosage numbers are offered to you since everyone uses different internal and external therapies, in addition to doing them in different ways.  In this sense, since each man is different, and each man follows a different plan, each man must determine what he must do to improve his scar behavior.

The procedure to determine scar size, shape, density and surface quality is explained in great detail in “Peyronie’s Disease Handbook.” The correct dosage of any therapy product is not determined from a chart. The chart that you receive with your first order only tells you the average range of what most men are doing. Your dosage should be what you need to take daily to cause changes in your PD scar. The dosage for you is what you learn works for you. I cannot tell you what you need to take. You have to determine that by your observation of the dose that makes the scar size, shape, density, and surface quality change. This vital information will guide your use of all the therapy products; it is the measurement that tells you if your plan is working or not. All of this is explained in great detail in “Peyronie’s Disease Handbook.”

Should I take Neprinol with other enzymes or by itself?

Hi Dr. Herazy, 

Should I take Neprinol with Fibrozym and Nattokinase, or just take it by itself?   Jerry 

Greetings Jerry,

Just so we are clear on what you are asking me, I know you are following a larger PDI therapy plan so I am confident you are also using other therapies besides the Neprinol, Fibrozym and Nattokinase you mentioned.   The way you asked your question I could get the idea you wanted to just use Neprinol by itself.  If that what you are thinking of doing, then I strongly advise against that.  I have never spoken to anyone who has earned good results by using Neprinol as a solo treatment for Peyronies.  You always want to diversify and broaden your treatment base with a variety of internal and external therapies, right?  

Men use Neprinol both ways – as a total substitute for the other enzyme products, or in addition to them (usually with the Neprinol being the primary enzyme source and the others being used as a minor role). The choice is yours.

I would consider using just the Neprinol as the only systemic enzyme, and see how it goes. If that is not enough to get the scars to change favorably, then bring back the Fibrozym, or Nattokinase, or Quercetin/Bromelain, or all of them into your existing therapy plan.

You must keep experimenting to learn what Peyronies treatment makes your scar size, shape, density and surface features respond favorably and then go with that.

What other Peyronies therapy or supplements should I consider at this point?

Dear Dr. Herazy:

I just started following the medium or  "better" program for PD. What other therapies or supplements should I consider at this point?

I was thinking about the Genesen Acutouch acupuncture system. Do you think this is a good idea?

If you could give me any thoughts you may have on additional Peyronies therapy, I would appreciate it.

Thank you for your time and care, your email was very informative.



Greetings Charles,

My suggestion is that right now you should pay very close attention to the size, shape, density and surface features of your scar, and faithfully follow your current Peyronie's treatment plan.  You should do this for 10-14 days to determine if your medium plan is able to favorably influence your scar.

if it does change your scar then all you need to do is continue with the medium plan just as you are using it until the changes of scar stop or your scar goes away. 

If it does not change your scar then you need to modify your current plan – not add to it – in some way.  With the medium plan this is usually to increase the dosage of MSM, Fibrozym, Nattokinase or Scar-X.  Then you continue for another 10-14 days to see if this plan modification was able to makes changes to the size, shape, density or surface features of your scar.    

if it does change your scar then all you need to do is continue with the modified plan just as you are using it until the changes of scar stop or your scar goes away. 

If it does not change your scar then you need to modify your plan again in some way.  You continue with this slow increase of therapy for a few cycles.  If at this point you have run out of ideas, then please contact me and we can discuss your situation.     

Yes, the Genesen pens are a great therapy for several reasons.  Probably the first is the power of these pens to treat a wide variety of problems; a book is included that lists how to use the Genesen pens to treat over 100 different conditions.  Then you have the ability to duplicate a very expensive level of treatment without incurring a great expense.  Also, you can treat yourself and your acupuncture points more often than you could afford to do so if you were going to the office of a professional.  The Genesen pens are often the difference that boosts therapy results from so-so to significant.  You might consider buying them later if it becomes apparent that you need extra help. 

Let me know how I can help you.   TRH

What is the average age for onset of Peyronies?

Greetings Dr. Ted, 

Thanks again for all the information you have provided in the past. My curve has gone from 60 degrees to less than 10 degrees.  I can't believe all this change in just 13 weeks after only getting worse for the last three years.

One more question that I have is about my age when my PD started.  I am 36 now and I got PD when I was 33.  According to most sites you read it states that occurrence typically is after age 55+, and some even say 40+.   Although I am sure there is great variation, does 33 seem young or typical given your experience?

Thanks again,


Greetings Gary,

No, 33 is not especially young to develop Peyronie's disease.  I, unfortunately, communicate with many men your age and even younger who have PD.  Last week I was involved in a lengthy discussion with a young man of 18 years who has had a diagnosed case of PD for almost two years. It does happen.

Age is less of a factor in Peyronie's disease than people would like to think, and the numbers are not absolute.  Just as you have stated that many sources report that PD usually occurs in men 40+ or 55+ or whatever age you might read, that does not mean there is a wall protecting you for the next few years if you are 37 years old.  While it is true Peyronies disease is a problem of older men, you youngsters can develop it also.  I would not put too much emphasis on that entire subject of age and PD.

The real question is now that you know you have PD, what are you going to do about it?  Let me know if I can help you tweak your plan a bit more to increase the rate of your improvement.  TRH

What is the best combination of products for treatment of Peyronies?

You may not be the one to ask but what is the best combination for treatment of Peyronies?  I have read and seen so much, my head is spinning. Thank you. Sonny

Greetings Sonny,

Probably a good place to start is by looking at the structure and diversity of the three Peyronies treatment plans (small, medium and large) that are shown and described at the top of the page of the treatment page on the PDI website. 

These different plans were put together so you can see how a balanced and diversified plan looks, and to make it easy for men to purchase a plan as a simple starting point for natural Peyronie's treatment.

Ultimately the best plan is the one that reduces the size, shape and density of your Peyronie's plaque.  This is determined over time by monitoring your PD scars while you are self-administering any plan you put together for yourself or have selected from the three PDI offers you.

To get to the point of your question about the "best": there is no best for everyone. You must search it out based on what works for you.

I think people come to the PDI looking for the "best" PD treatment in the same way they go to their doctor looking for the best drug to reduce their high blood pressure or the best salve for their rash.  In the PDI method of treatment we realize their is no one single Peyronie's treatment; we realize a combination of treatments are used at the same time to encourage and support the body to heal the PD plaque.  Further, we realize that this combination is different for everyone.   So each man starts out using the plan that he thinks might help him, and is prepared to modify it later if it does not make the necessary changes in his scar tissue.  This is why it is so difficult to answer the question "What is the best Peyronie's treatment?"   Each person must work that out individually.  I can help you with that process.  TRH      

Can you tell me how long the PDI middle plan will last?

Hello Dr. H,

My husband is considering the middle plan for his Peyronie's. Can you tell me how long it will last him?

Thank you!

Karen A.

Greetings Karen A.,

Many people want to get an understanding about rate of product usage, so yours’ is a common concern.

Each person approaches his Peyronie's disease treatment plan a little differently, not only in regard to size of treatment plan and overall direction of therapy, but especially in terms of dosage.  Some men take all their PD therapies in a very conservative way, some men take all their PD therapies in a very aggressive way, some men take 1-2 of their therapies conservatively and a few very aggressively, other men do not follow their plans very faithfully and so forget to do what they should do.

Because of this, each bottle and each therapy plan will last for a variable length of time.  In other words, not all men who get a Medium Plan use it in the same way or at the same rate.  So, how long individual bottles of any therapy plan will last is a personal and variable issue for which I can only give you approximations based on what I see others doing.

Based on my experience with others who use a PDI Medium Plan, the average person re-supplies the DMSO and Super CP Serum close to once every 3 months, while the Factor 400/400 and Maxi-Gamma E, C, Scar-X and MSM about every 4-6 weeks, and the systemic enzymes every 4 weeks.  Of course, the Massage and Exercise video CD is never replaced.  based on many years of experience working with men who use all of these plans, the average man will spend about $75-100 monthly to replenish the Medium Plan, after he makes his initial purchase which will be the greatest expense.  To state it another way, the Medium Plan costs around $210 to start, and about $75-100 per month to continue.     

In addition to the usual information that comes with your plan, I would suggest that you really should get the book I wrote about PD, “Peyronie’s Disease Handbook.”   In chapter 4 of this book you will learn the essential skill of how to determine the size, shape, density and surface features of your scar so that you will know exactly how to regulate your intake of therapy in your plan.  In addition, the book also gives a wealth of practical information that you can easily use every day to make life with PD easier and less stressful.  This popular book gives treatment suggestions and a dietary approach to PD that are not found on the PDI website; actually, the book is most helpful and valuable in treating PD, but in a much different way than what is found on the PDI website.  Check it out.   

Good luck to you and your husband.  Let me know if I can help in any way. TRH



Why is acetyl-L-carnitine not mentioned on your website?

I'm wondering why is Acetyl-L-carnitine not mentioned on your website for treatment of Peyronie's disease?  I have read some really strong research findings about acetyl-L-carnitine and am eager to try it out.  

Thanks, Bruce

Greetings Bruce, 

You are incorrect, Bruce, acetyl-L-carnitine is mentioned often. We have highly recommend the use of acetyl-L-carnitine since 2002. 

Please go to this large page on the PDI website that explains what you need to know about this excellent PD therapy,  Acetyl-L-Carnitine and Peyronie's Treatment.   For a bit more go to the PDI store to read Acetyl-L-Carnitine where I refer to this therapy as an All-Star product. 

To learn how to use this therapy product, and others, for ideas and suggestions to put it all together, go to the Peyronie's Disease Institute website for all the information you might need.  TRH

Why are two different vitamin E products made available?

Why are 2 different Vitamin E sources (400/400 and Gamma E) suggested in your therapies?  What are the differences? Would only 1 suffice in an effort to help manage costs?


Your question about the reason for the two different types of vitamin E to treat Peyronie's disease is a common one.  Thank you for bringing it up again.

I cannot put an entire detailed answer to your question in this reply. Let me just comment that the Maxi-Gamma vitamin E is used because it provides a higher ratio of the Gamma type of vitamin E that is helpful in healing and removing scar tissue.  The other vitamin E product, Factor 400/400, is a balanced vitamin E providing all eight types of vitamin E that does not emphasize the Gamma type the way the other one does.   When used together they complement each other and work nicely to provide an excellent and highly concentrated source of vitamin E that will assist your body to correct your Peyronie's disease to the best of your ability. 

To get the full answer and to learn more about vitamin E in a Peyronies treatment plan, go to Vitamin E for Peyronies treatment

Sure, if you used only one type of vitamin E it would manage costs.  But, which one to use?  I do not have a clear answer on that one because I can make a good argument for both of them as being the one you should use if you were going to only use one. 

If you must use just one, then I suggest you experiment a bit by using one of the products in your overall plan to see how you respond, and then use the other one to see if you respond differently to it.  Of course, this is how I suggest that anyone approaches any of the therapies to see if it should be included in a therapy plan.  TRH

Should my husband have a penile implant?

My husbands penis curves 90º upward when erect because of Peyronie’s disease and has painful intercourse. We believe it’s from an injury he sustained during intercourse about a year or so ago. We have seen a urologist several times and have been told our only real option is a prosthesis. Do you think your program could help us?


It is not my intention or desire to interfere between your husband and his urologist concerning any aspect of his treatment or his relationship with his doctor.  I will not answer your question directly if your husband should or should not consider having a penile prosthesis surgically implanted to resolve his current sexual problem – I have no direct opinion or advice for your question.  That is a subject for discussion between the two of you and your husband’s treating doctor.  My only interest and purpose in making this reply is to offer general ideas, and pose questions to you, to broaden your discussion with the urologist about the progression of your husband’s care.

My general opinion on this subject and ideas for you to consider, as you make up your own minds about his treatment, are these:

    1.  The penile prosthesis is a mechanical device that induces an artificial state of erection – either temporary or permanent –  so that intercourse can take place.  It is usually thought of a surgical treatment for Erectile Dysfunction, and less so for Peyronie’s disease. Regardless of the type of penile prosthesis that is used it is necessary to surgically remove all or part of the corpora cavernosa (the bulk of the internal tissue that gives body to the penis) to make room for the prosthesis.  Once this is done the penis can never be returned to normal.  If there is some reason (massive infection, his body rejects the foreign material of the prosthesis, failure of the device) to remove the prosthesis, his penis will be just a small shell of what it once was.

    2.  There are several basic types of prosthetic devices, and each has its advantages and disadvantages.  Which one is suitable for a patient is often determined during the actual operation when internal measurements can be made. Sometimes it happens that the patient wants one thing, but the surgeon is not able to provide that option because of anatomical problems.  The type of prosthesis to use is a huge subject and one that is very important for you to consider ahead of time.  I suggest that you go to several websites to research what your actual options are for each type of prosthesis, and what are the pros and cons of each.  Some sites you can visit are    and

    3.  While it is stated that 90%-95% of inflatable prosthesis implants produce erections suitable for intercourse, it is important to note that this must mean that 5-10% of  inflatable prosthesis implants produce erections that are not suitable for intercourse.  In my opinion for 5-10% of men to wind up having a non-functional erection after going through a gruesome surgery so they would have a functional erection, is a huge failure number.  The medical profession is proud to tell patient that the rate of patient satisfaction is very high with penile prosthesis use, and state that somewhere in the range of  80%-90% of men are satisfied with their results.  Again, I look at it from other direction and think about the 10-20% of men who are not satisfied with their device after going through the surgery.  Many people I communicate with are disappointed because of the lack of natural feel and natural appearance of the penis after surgery, the partial or total loss of sensation, the occasional or constant pain they experience, and/or the feel of something foreign in their groin area.  They must either continue to let it remain inside their body or remove it and be left with a flap of skin. 

    4.  Very few of the websites that discuss penile prosthetic surgery provide much detail about surgical failures and adverse surgical reactions. No surgery is totally free of possible direct complications, and penile implants have their own unique list of  possible complications:

  • Infection, and even recurrent infections that return long after the surgery is over
  • Uncontrolled bleeding after surgery, possibly leading to re-operation
  • Scar tissue formation, especially important in someone who already has Peyronie’s disease
  • Tissue erosion and breakdown internally where the implant touches tissue, leading to eventual removal
  • Accidentally cut nerves, arteries or veins that lead to unintended consequences like pain, numbness, coldness, and/or chronic edema 
  • Mechanical failure of the prosthetic implant, leading to re-operation and removal

I have communicated with hundreds of men whose penile implant surgeries have gone bad.  Some doctors might mention post-operative infections, and even severe post-operative infections, but they do not elaborate what that really means in terms of possible long-term consequences to the patient and his partner. As a result of infections that occur, scar formation and unintentional cutting of nerves, arteries and veins the patient is left with more problems than before his penile implant surgery.  A man can be left with partial or total loss of sensation that means partial or total numbness of the penis no sexual stimulation or pleasure is felt.  He can be left with temporary or permanent pain, of a mild to severe nature, that is made worse by anything contacting the penis.  I have communicated with men whose only option after several failed penile surgeries was amputation.    

    5.  Most people who write to me about surgical options for  Peyronie’s disease are considering an operation that will correct the curvature, not install a foreign device. What is the reason you were given to not do a Nesbit procedure or a skin graft?   Most often, after the Nesbit or skin graft fails only then, as a last option, is a penile implant suggested.  I am curious why in your husband’s case the implant was suggested to start.  While I am not a big fan of the Nesbit and skin grafting options, they are still more conservative than a penile implant.

    6.  It makes sense to me to first attempt more conservative options; options that do not have permanent and irreversible consequences. If this makes sense to you, you could consider spending a little time on the PDI website learning about the conservative options available to you.  

   7.  There is no way for me to tell you in advance if the Alternative Medicine methods of PDI will help your husband.  It is something that has to be worked on over time to determine if he is capable of supporting and enhancing his immune response to eliminate the Peyronie’s plaque that is causing his penile curvature. 

In college a wise professor repeated frequently to our class, “There is never a perfect situation.”   As I grow older I understand the importance of keeping this in mind.  When it comes to the often imperfect nature of surgery of any kind, it is better to be conservative at the onset and gradually play out to more aggressive and potentially risky options as your conservative choices are used up – not the other way around.    

Good luck in discussing this subject with your urologist.   TRH


Will erections further injure my penis?

Dr. I have ED, used ED meds and now have Peyronies. Have stopped the Med use but still get erections at night. Will getting erections further injure my penis ?


No, erections will not further injure your penis.  Based on your brief explanation I suspect your penis could have been injured more so by the prescription medications you were given for your ED.   My suspicion is that you were given a prescription for one of the  PDE-5 (phosphodiesterase-5, like Cialis, Levitra or Viagra) drugs.  Taking one of these could have produced an excessive reaction in which the erection caused more internal pressure than was healthy for you.  This, in turn, could have resulted in damage to the internal penile tissue and hence Peyronie’s disease. 

If you now notice pain while erect since you have Peyronie’s disease, this does not mean that the erection is necessarily bad for you.  The erection is simply stretching inflamed internal penile tissue related to the PD.

You might also find reading Peyronie’s Disease and the Erection  to be helpful to understand this subject. 

I suggest you avoid the PDE-5 erection producing drugs in the future, since they could possibly injure you further now that you have Peyronie’s disease.  Consider investigating the non-drug erection producing herbal and mineral products that will not risk injuring your further.   TRH

Should I continue penile injections for Peyronies treatment?

I have Peyronie's disease causing a bend to the left and downwards and it's closer to the tip then the base. I have seen a urologist who has injected it twice now. I haven't seen any improvement. both my doctor and myself have trouble finding any plaque. I'm 50 and in good shape….this just showed up a couple of months ago…there was no trauma…should I continue with the injections?  .


It is not my intention or desire to interfere between you and your urologist concerning your treatment or any other aspect of your relationship.  Nor will I answer your question directly if you should or should not continue with the penile injections you are receiving – I have no direct opinion or advice for your question.  That is a subject for discussion between you are your treating doctor.  My only interest and purpose in making this reply is to offer ideas, and pose questions to you, to broaden your discussion with the urologist about the progression of your care.

My opinion and ideas for you to consider are these:

    1. Any time you make a simple injection into the penis with anything, even sterile water,  you are physically traumatizing the thin tunica albuginea membrane where the Peyronie's plaque is located.  Many times when these injections are given at multiple sites of the tunica albuginea at one office visit, causing multiple trauma.  Yes, these are small needle holes, but they are holes none the less.  When given at multiple sites within a small area, and done on multiple occasions, that is still a lot of trauma (think of a shot gun blast which is just a lot of small holes). Your body has already demonstrated the tendency and ability to lay down excess collagen in the form of Peyronies plaque without any trauma or trauma so small that you do not remember it, so what will be its reaction when actually traumatized?  It is my opinion that any injection is a direct injury that could possibly cause more plaque or scar tissue to develop or worsen plaque already present. 

Avoidance of the trauma of needle injection is the reason that since 2002 I have counseled perhaps 20 or so MDs (of whom 2 were urologists) who had PD and wanted to avoid surgery, injections and drugs. 

    2.  The needle injection points are not the only potential trauma to the tunica.  Since you did not mention what drug was being injected by your doctor, I cannot comment specifically on that issue, but it is my opinion any drug has a potential to cause chemical trauma in the form of an allergic reaction, side effect or perhaps just a chemical irritation to the tunica in certain individuals.  If this is the case with you, this could result in additional irritation internally and further trauma to tissue that has already created Peyronies plaque for no apparent reason you recall.  It is my opinion that any drug reaction or unexpected side effect could possibly result in additional  plaque or scar tissue or further aggravate plaque already present.  

Unexpected drug reactions and unexplained side effects are a fact of life in medical practice.  This is such a large problem that there is a medical term for it, "Adverse Drug Reactions" or ADR.  In fact, a 1999 report in JAMA of a meta-analysis entitled "Incidence of Adverse Drug Reactions in Hospitalized Patients" by J. Lazarou concluded that

             "The overall incidence of serious ADRs was 6.7% (95% confidence interval [CI], 5.2%-8.2%) and of fatal ADRs was 0.32% (95% CI, 0.23%-0.41%)
             of hospitalized patients. We estimated that in 1994 overall 2216000 (1721000-2711000) hospitalized patients had serious ADRs and 106000
             (76000-137000) had fatal ADRs, making these reactions between the fourth and sixth leading cause of death.



             Conclusions.— The incidence of serious and fatal ADRs in US hospitals was found to be extremely high."

I am not at all suggesting that any penile injection could cause a fatal reaction, but I am suggesting that if in hospitals serious and fatal ADRs occur at the rate of 6.7%, the rate of less serious ADRs must be even higher.  All of this means that drug reactions occur at a seriously high rate, you are taking drugs directly into the penis, and you are already in a position in which you should be extremely careful because your penis will probably overreact if it is further injured.   

    3.  If you say that you and your doctor have trouble finding any plaque, then where are these injections being given?  If the exact location cannot be confidently identified by your doctor, then how accurate is the placement of these injections you are receiving?

    4. It is estimated that 50% of men who begin Peyronie's disease will self-limit or cure their own problem without any outside help or medical care.  The  Alternative Medicine treatment concepts of PDI is simply to do all that you can with natural methods to increase the natural healing ability of your own immune system to eliminate your Peyronie's plaque.  How to go about doing this is the subject of the large PDI website.  I suggest that you, and everyone else with Peyronie's disease, consider attempting conservative measures before undertaking more aggressive Peyronie's treatment that has potential for side effects and drug reactions.     

Good luck in discussing this subject with your urologist.   TRH    

Benefit of VED for treatment of Peyronie’s disease?

Dr. Herazy,

Do you recommend or see any benefits for using a Vacuum Erection Device (VED) for the treatment of early stage Peyronie's Disease when the patient has no difficulty achieving a normal erection by sexual stimulation?


Generally, like with most things related to Peyronies, I find men saying different things about the VED; some say it helps and some say it does not and others say it caused their PD.  The greatest limitation I find is that whatever stretching of the penile tissue occurs using the VED is too general.  To do any good in Peyronie's disease treatment the stretching must occur only and specifically at the site of the scar, not the entire organ.  To do this I developed the Peyronie's Disease Institute Manual Penis Stretching Method described in this video.    

Another way to look at the subject  of the VED is in regard to the current level of injury and vulnerability of your penile tissue at this time.  You already have a problem, and the problem often starts from a very small injury – sometimes so small that it goes unnoticed.  The VED will apply perhaps up to 100 PSI to your tissue; enough to often break blood vessels and tear tissue.  This amount of force applied to the penis that already has shown a tendency to over-respond to injury by creating excess scar tissue does not sound like a good idea to me.  TRH

How to use Thatcher’s formula for Peyronie’s disease?

Doctor, I have one question. How does someone use Thatcher’s Formula (DMSO + Castor Oil + copper) for Peyronie’s disease? Over the last few months I have researched various PD topics I have found a few random posts about this formula and how to apply it using flannel and warm heat…if you have any more specific information, would you kindly pass it along? Thank you for your time and information, Bill

Greetings Bill,

Yes, I know about using Thacker’s formula. Thacker’s formula has bounced around a lot for many years in Peyronie’s disease discussion groups, and has achieved something close to cult notoriety.

The first thing you should know about Thacker’s formula is that it does not contain copper. It contains, DMSO, castor oil and apple cider vinegar. It is essential that you do not use this therapy, or any other, based upon what you pick up here and there on the various Peyronie’s forums where many untested and untrue ideas are promoted – like the notion that Thacker’s formula contains copper.

My suggestion to you is to first use a well balanced and aggressive Peyronie’s therapy plan such as you see on the PDI website, while you carefully monitor your scar for changes in size, shape, density and surface features to give evidence to your progress. Our PDI therapy plans have been used since 2002 with success and are based on reasonable science and positive research findings. This makes more sense to me than using Thacker’s formula by itself. I would agree that you should consider using Thacker’s formula along with other therapies in a combined effort, just as we recommend combining other PD therapies for best effect.

Please let me know how I can help you during your therapy effort. TRH


Too late for help after Peyronie's surgery?

Dear Dr. Herazy,

My husband developed Peyronie's disease almost seven years ago after an injury while making love. His urologist first did a series of injections with verapamil. When that did not help he talked us into surgery by saying that it was the only way to straighten his 90 degree curvature. The surgery went very badly and now his curvature is worse and he has no feeling in his penis. He has become withdrawn and is very angry with himself and takes it out on me. i am so glad to have finally found your non-drug website and only wish we had found it sooner before the surgery. Do you think it is too late for my husband to get help from your alternative medicine treatment ideas?

Thank you.

Marge V.

Greetings Marge,

Sorry to hear of your husband's bad reaction to Peyronie's surgery.

There is no way I can answer your question directly, since there are far too many unknowns and variables. However, I can tell you that many men who have had bad Peyron

buy viagra online

ie's surgery results have seen a reduction of scar tissue after following a PDI treatment plan; some of these changes were very small and some were remarkably great. The work is always long and difficult because of the complications of additional scar tissue, but always worthwhile for any reduction of numbness and reduction of other problems such as curvature and pain that can occur. There is no way to tell ahead of time if your husband is capable of any change in his scar tissue, but if some can be made it could result in some degree of improvement of his current sad situation.

I suggest that you get both of my books and that you and your husband read them, especially “Peyronie's Disease & Sex.”

Go slowly with your husband and do not push him too much to follow any of these ideas, He is angry and scared about injuring himself more with any kind of additional treatment, and most of all he is embarrassed. Give him some room to warm up to the ideas of safe Alternative Medicine care. If he has any questions or hesitation please encourage him to email me directly. I will try to help him as much as I can. TRH


Do I need your book or a doctor?

Thanks Doctor, I'm 64 and do a lot of heavy exercise. Yesterday I got a hard-on ….and for the first time time there was a break (left bend in the bottom third of my penis). Do I need your book or a doctor? Thanks. Mike Adler

Greetings Mike,

What you really need is to know for sure what is going on with that bent penis. The best way to do that should be to go to a doctor for an examination and diagnosis. The problem is often that the doctor does not know, does not want to take the time, or does not seem to care about dealing with Peyronie's disease. Even after a medical examination it is common for a man to still be unsure if he has a correct diagnosis.

I suggest that you get a very good medical examination or at least in some way come to a point where you are confident with the condition going on below your belt. It is not always easy, however, so be prepared.

If you wish to learn more about treating PD I urge that you start with the book I wrote, “Peyronie's Disease Handbook.” It will ground you so you know how to deal with PD from a physical and mental standpoint, treatment concepts, how to develop the essential skill of determining the size, shape, density and surface features of your Peyronie's plaque, and how to avoid doing things that can cause additional injury to yourself.

Let me know if I can help you in any way. Good luck. TRH

Change Peyronies Treatment Dosage

How to change Peyronie’s treatment

Starting Peyronies treatment dosage can be easy if you start by taking therapy products at the manufacturer’s suggested rate – perhaps for the first 14-21 days.  If this dosage causes a change in the size, shape, density and surface qualities of your scar(s), then that simple and small dosage is adequate to provide you with the help you need to eliminate your Peyronie’s disease scar formation.  

This is a list of all therapy products available through Peyronie’s Disease Institute and Natural Health Education LLC with the manufacturers’ suggested dosage:

1.   Vitamin E Factor 400/400 (60) – 1 or 2/day – with food
Maxi-Gamma E (60) – 1/day – with food
Unique E (180) – 1 or 2/day – with food
Natural C 1 gram (100) or (250) – 1 or 2/day – with food
Ascorbplex (90) or (180) – 1 or 2/day – with food
Fundamental Sulfur (100) – 3/day, taken between meals, or if upset occurs, – with meals
Acetyl-L-carnitine (60) – 1/day – with food
PABA (100) – 1 or 2 daily – 1/day – with food
Quercetin Bromelain ((100) – 1-8/day – between meals
Fibrozym (100) or (200) – 2 tablets, three times a day – between meals
Nattokinase 1500 (120) – 2 tablets, two times a day – between meals
Neprinol (90) or (300) – 1-4 capsules with 8 0z of water – between meals
Scar-X  (1 oz) – 10 drops three time a day – between meals
PMD DMSO Gel (4 oz) – 1-3 times a day, depending on skin tolerance
Super CD Serum (1 oz) – applied to skin before PMD DMSO
Unique-E Vitamin E oil (1 oz) – applied to skin before PMD DMSO
HJG and KBG Honso herbs – 1-3/day
Genesen Pointers – used 15 minutes or longer, daily if desired
Massage and Exercise instructions – performed 2-4 times a week
20.Gentle Manual Penis Stretching Method © instructions – used 15 minutes or longer, daily if desired
21. Prosta-Support (120) – 4/day – with meals
22. color: black;”>Omega T – 1 or 2 daily – with meals

Peyronie’s treatment dosage example
Let us say that you decide you will take PABA at a dose of 2/day. After doing this for a reasonable time – maybe 10-14 days – you do not notice any change in your plaque or scar at the 2/day dose. In this case you probably should consider increasing dosage until your scar responds to your therapy.  The usual method is to simply increase the dosage by one capsule or pill to the total every few weeks until you notice change in the size, shape, density or surface features of the scar.  

The process is made more complicated by the fact that you should be taking multiple therapies, but that is necessary to achieve results.

Peyronies dosage determined by scar response

To know exactly how to modify your dosage it is necessary to compare the size, shape, density and surface features of your scar from the onset of treatment. This critical information enables you to recognize positive changes when they occur. If you do not know how to determine and record the size, shape, density and surface features of your scar you will have to refer to chapter 4 of the “Peyronie’s Disease Handbook” to learn about scar measurement.   

All dosage increase is done slowly and carefully over a period of time to allow the body the opportunity to respond to a favorable change in therapy. If the dosage is changed too rapidly or too often it will not be possible to determine what factor caused a favorable response.  If you develop any unusual symptoms or change in body behavior or appearance while increasing dosage, simply stop taking the product for 48 hours after that problem/symptom disappears. Restart after 48 hours or when the new symptoms clear up, using the next lower dose.  From this point forward, once again begin the process of increasing dosage to promote favorable scar change. After reaching a higher dose at which changes are noted in the scar, remain at that dosage level for a few weeks.  Your correct dose is discovered by accompanying improvement in scar size, shape, density or surface quality.

Discuss your PD therapy plan with your family doctor or urologist so he/she is fully aware of what natural Peyronie’s treatment you are following.  You should consider this discussion about dosage strategy after getting final approval from your doctor. 

Does Peyronies last forever?

Does peyronies last forever, or is their an estimate to how long it lasts? Thanks.


Here are your short answers: Peyronie’s disease can last forever, but in a large percent of cases it does not have to if the man actively and aggressively works to increase his healing ability against PD. And, PD can last a life time in those men who do nothing about it.

In about half of the cases of Peyronie’s disease, the disease will be self-corrected or eliminated without doing anything about it. The body heals and eliminates the PD problem naturally like it heals and eliminates thousands of other health problems.  In the other half of persistent cases, the problem tends to continue indefinitely unless it is treated with Alternative Medicine methods that increases the body’s ability to self-correct and heal the Peyronie’s plaque.

For those men whose Peyronie’s disease does not go away on its own, they tend to be very active and motivated to get help for their problem. But after talking to a few MDs, reading a few online websites or asking a few questions on Peyronie’s forums, they eventually learn the standard medical answer that there is nothing that can be done for Peyronie’s disease – that there is no cure for PD. After learning this from multiple sources they tend to get depressed and discouraged and stop looking for help. Since they accept defeat, and never start to assist their natural recuperative abilities, their PD tends to either stay the same or slowly worsen over time. Some men report slow gradual improvement of their PD while other men report slow gradual worsening, the opposite. These contradictory reports of long term outcome of what eventually happens in Peyronie’s disease is consistent with the extremely variable and contradictory nature of this problem.

So in this sense, I suppose you could find different opinions about how long Peyronies lasts. Given the variable and contradictory nature of PD, most men agree that they do not want to risk that their PD will get better in 10 or 20 years. They get active and they get started working a PD treatment plan as we discuss throughout the PDI website. A good place to start learning about Peyronie’s treatment is on the Peyronie’s Disease Institute website.


Dimensions of girth prosthetic rings?

The dimensions of the girth prosthetic rings are not given.

I see that this information was omitted. Here you go:

Large ring: 2 5/8″ long X 1 5/8″ wide with a 5/8″ opening

Small ring: 1 3/4″ long X 1 1/2″ wide with a 5/8″ opening.

Please bear in mind that although the 5/8″ wide op

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ening in the center of the rings is small, the material is very elastic and will stretch to fit and accommodate your particular girth and degree of curvature. This firm hold is needed to provide lateral support against sudden and dangerous bending.

This prosthetic device is very popular and assists to provide extra support for the bent penis to avoid additional injury, or when the penis is narrowed by plaque formation. TRH


Age 17: Is my bent penis Peyronie’s disease?

Hey Dr. Herazy, I am 17 Years old and have noticed this curvature in my penis for as long as i can remember. Ive been doing some research on different treatments for Peyronie's disease. . I was wondering what, if any, vitamins can I take that will help remove the plague or increase the blood flow through the affected area. I want to try all of my options before I turn to surgery. And also I am sexually active but self-conscious as to what females will think when they see my PD. What should I do ?


First things first: At the age of 17, if you have had a penile curvature “for as long as you can remember” it is not likely to be PD. Your curvature is most likely a normal anatomical variation that makes you the unique person you are.

No need or reason for embarrassment. In my 2nd book, “Peyronie's Disease & Sex” I spend considerable time explaining in great detail how many women prefer

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a bent penis because it — shall we say — scratches their itch in a way that a straight penis does not. In that book I counsel men that if you have a bent penis — either from PD or from a congenital variation — rather than sitting embarrassed in a corner afraid of being rejected, they should look for that wonderful woman who needs a man whose penis is bent. Your task is almost like looking for the right lock that fits your key.

You ask what you should do. I strongly suggest that you get to a urologist who is experienced with Peyronie's disease and get a diagnosis of what is actually going on with you. At this point you are making an assumption, and that is not the way to approach this situation. Do not guess about PD. When you know for a fact you have PD — at this point I believe you do not have PD — then get back to me and I will guide you through natural treatment. TRH

When and how do I make changes to my Peyronie's treatment plan?

Hi again Dr. Herazy,

Just one more question. I am beginning to see changes in my scar, like softening and reduction of the scar. . What I want to know is, when and how do I make changes to my Peyronie's treatment plan?

Jeffery C.

Greetings Jeffery,

Progress or lack of progress with your Peyronie's plaque is what determines when you change your plan and what changes you make to it. As I have said so many time before, “The scar dictates treatment.”

If you are currently making satisfactory changes in your scar, do not change anything. If you are not making satisfactory changes in your scar, you should think about making a positive change to your plan.

Do you have the 1st book I wrote, “Peyronie’s Disease Handbook”? If you do not have it, then you will not know about monitoring your current condition. If you have it, then you can use this information to guide you to increase or decrease your plan as your PD dictates.

For you to know for sure that a recent treatment plan modification is effective you will have to notice some positive change in your scar (softening, fragmentation, smoother edges, etc.) within 10-14 days of the change in your plan, perhaps faster. I would make some logical change (usually an increase of an existing therapy item or a new therapy item if your plan is small) and then wait at least 14 days before looking for a change to occur in the size, shape, density or surface qualities of your scars, before considering another change.

In the beginning of care it might be necessary to only add or increase one therapy if you are at a lower level of therapy (just starting to take the medium plan). In the early stages of therapy modification you will likely keep slowly adding to your plan, one therapy (only PABA or only MSM or only Neprinol only or whatever single item you decide to increase) at a time, by adding 1-2 pills per day. It is not wise to go too quickly from one level to another (like taking Neprinol at 6/day, and then jumping to 14/day; this is too fast and you might not need to take so many for good changes to occur). After a while, when your total number of pills is getting to a point where you might think you simply do not want to take more pills/spend more money, then at that point you might consider this a good strategy: modify your plan by decreasing one therapy slightly as you increase another therapy slightly. This way you are not overwhelming your system with unreasonable loads of pills and you are not spending an extreme amount of money.

Be gradual with your changes. Keeps good notes about your scars. Let me know if this did not answer your question. TRH

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Question about Peyronie’s CD video

I also forgot to ask I had previously ordered the video … However I want to order the medium package but I do not need the video again…do you offer a discounted price if I do not need the video….just curious appreciate your help…Thanks


I will answer your question in two ways. The first answer will be based on the error I think you have made in your question, and the second will be an answer as you have asked your question.

First, based on an error I think you made: There are actually two CDs that PDI has available. There is an Exercise and Massage CD — that is a part of the Medium and Large PD plans. And there is a Manual Penis Stretching CD — that is not part of the Medium and Large PD plans. It is rare that anyone orders the Exercise and Massage CD by itself. Most everyone who orders a CD by itself will order the Manual Penis Stretching CD. This is what makes me believe you ordered the Manual Penis Stretching CD — which is not included in the Medium Plan you want. You really should get and use the information in the Exercise and Massage CD because it is an important part of any good Peyronie's treatment plan. I encourage you to get the full Medium Plan so that you will be able to go about following the treatment as you should.

Second, the way you asked the question: No, there is no way within the way the system is set up to add a discount to an already discounted item, such as the medium plan. if you want to order everything in the medium plan except the Massage and Exercise CD (meaning the Maxi-Gamma and Integral E 400/400, MSM, nattokinase, etc) then you will have to order them separately.

Please let me know if I can help you with your Peyronie's treatment questions. TRH

Do you give any discounts for repeat customers?

Do you give any discounts for repeat customers? Thank you.


Yes, we do offer discounts, but they are available to everyone — repeat customers and new customers. These discounts are available each time you place an order with PDI. Some are automatic and some you must enter a discount code.

We attempt to offer the very lowest prices for our pharmaceutical grade therapy products to everyone who orders from PDI, and our sister-website for Dupuytren contracture at DCI.

Everyone is concerned about discounts and keeping costs down lately, and Peyronie's treatment can be expensive.

Our prices are already the lowest you will find anywhere for the high quality product line of pharmaceutical grade therapies. Please bear in mind that not only are our prices outstanding and our products have been shown to be effective with PD when used as suggested, but our SERVICE is even better – and it is service, information and experience to help

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with your treatment that you must consider when you are treating your Peyronie's disease. What you are receiving from PDI – even more than great products at a great price – is the time and effort given to you to provide the experience and insight into successfully treating your PD.

If you decide to purchase your different therapy products elsewhere based only on price you will be using untested and unknown brands that right not actually contain what their label claims. This is always the problem with purchasing based only on low price.

These are the discounts PDI offers:

1. Standard and automatic 10% discount for all Small, Medium and Large Treatment Plans.
2. TRH10 — $10 off each order of $200 or more
3. “neprinol” — $9.99 discount for a 300 count bottle of Neprinol
4. “neprinol90” — $25.04 discount for a 90 count bottle of Neprinol

Let me know if I can help you with your Peyronie's treatment plan in any way. TRH


What can I do to reduce the PD plaque?

i am 48 years old, and have had peyronie’s for approximately 5-6 years from unknown origin (but most likely from a crush injury). my condition has progressed to the point where i have a very significant plague that runs almost the entire length of my penis; the plague quite literally feels like bone, and is located more near the top of my penis (between the outer skin and urethra). my penis is not curved, but rather has shortened (fairly substantially) and has lost significant girth; while my erections are reasonably hard (though not as hard as previous to the condition), the overall size of my penis has reduced quite significantly. in addition, i seem to have lost nearly, if not all feeling in my penis, so much so that when i do have sex w/ my wife, i feel virtually nothing, where it takes me a very long time to reach orgasm, if at all. sadly, i most often fail to reach such; only very rarely am i able to achieve orgasm now. in fact, it is somewhat difficult for me to even know precisely how full/ hard my erection is unless i actually palpate such. i have recently returned to the united states (from living in china), and will now be able to resume taking a fairly substantial series of supplements recommended by you and provided from your company. what can i do to reduce the plaque, and to hopefully regain feeling in my penis? can i ever regain feeling? your assistance is greatly appreciated … eric

Greetings Eric,

Thank you for your detailed description and questions.

I am a bit confused by your description of the location of your Peyronie’s scar or plaque (part of your description sounds like your plaque is on the bottom/under side of the shaft and another part sounds like your Peyronie’s plaque is on the top/upper surface).

In my reply I will assume it is on the upper/top surface of the shaft as you are looking down at your erection, since this is by far the most common presentation of plaque that runs the length of the shaft. This plaque location is most often responsible for lost length and girth, such as you describe, and for generalized erectile dysfunction. Many men with PD experience localized reduction of erectile ability, resulting in soft spots, or nicks or dents or dings in various areas of the shaft. Yours sounds like the entire shaft is soft, often the result of plaque development within the septum of the penis (the point where the tunica albuginea that is around one corpora cavernosa touches or combines with the tunica albuginea of the other corpora cavernosa).

Your loss of feeling is not common; most men with Peyronie’s disease with have little trouble with loss of sensation. While lost penile sensation could be due to other factors unrelated to PD, I will assume it is related to the central location of your plaque compromising your nerve supply. If this is true, and I have no way of knowing for a fact that it is since I have not examined you, I assume that your penile sensation should return once your plaque is reduced. Besides reduced reduction of sexual sensation, do you also notice general loss of sensation to light touch or pain (as when you pinch the skin of penis)?

You ask what you can do to reduce the plaque. I saw in today’s list of orders that you purchased a large assortment of internal therapies (Acetyl-L-carnitine, MSM, Neprinol, Omega T, Quercetin-Bromelain, Factor 400/400 and Maxi-Gamma). However, you did not order any internal therapies (PMD DMSO, Unique-E oil, Super CP Serum, or Genesen Acutouch pointers). Both internal and external therapies are necessary for effective treatment. It is also necessary that you follow the dietary modifications outlined in “Peyronie’s Disease Handbook” to keep your blood pH toward the alkaline side. The stretching video contains detailed information how to address plaque formation found within the septum, such as you have. All of these therapies must be applied at the same time to achieve best results.

You will probably have to modify your plan to achieve favorable changes to the size, shape, density and surface features of your plaque. Do not be slow in making those changes to your plan when you see that after 10-14 days of treatment the plaque is not responding. For this reason it is absolutely critical that you clearly can identify the size, shape, density and surface features of your plaque. I know I might sound like a broken record when I continue to repeat this, but if you do not know these four aspects of your plaque description, you are only guessing at your treatment. Please, do not guess. Know what is going on down there below your belt and you will have an excellent way to direct and guide your therapy toward the greatest degree of success of which you are capable.

Please stay in close contact with me as you begin your self-directed therapies. Let me know of any problem or questions that arise, and I will be happy to offer you information and ideas for your consideration. TRH