What Peyronie's treatment options or products are currently available from PDI?


I'm 35 and about 2 months ago, I noticed a slight deviation on my erect penis (right side) and when I mentioned it to my urologist he said I may be developing Peyronie's Disease. I am concerned it will get worse. I'm wondering what treatment option(s)/products you currently have available on your website you think I should consider to correct this.


Greetings Joe,

There are well over 500 pages of information about using Alternative Medicine for treatment of Peyronie's disease on this website. It seems like you have not looked around the site very much or you could not have asked this question.

I suggest you go to Peyronie's treatment products page to see the list of things you can use to improve your ability to heal and eliminate the Peyronie's plaque. With just a little effort on your part you can get an idea about putting a plan together for yourself if the large, medium and small plans do not suit you. You can get lost in this site for a few days reviewing all the information that is readily available to you. Just click on a few links and see what you can learn. TRH


Connection between dental problems and Peyronie’s disease?

Dr. Herazy- I have had bad health for the last four years and have developed peyronie the last year and a half.
I have had a cough-skin problems-fatigue etc. I have been getting better and think that most of my issues were related to terrible dental infections. I have had 10 teeth pulled in the last year and they all were black/green below the gum line.

I am also getting three more pulled monday.

Could have caused my peyronies?



Sorry to hear of your recent health problems.   Glad you are taking care of yourself and getting better.

The only remote connection between your dental infections and Peyronies disease might possibly be related to some drug reaction from the combination of different medications I assume you were prescribed over the last few years.  I suppose there is always the possibly that your depleted immune system  might have allowed this genetic problem to get out of hand.   Otherwise I am not aware of an direct relationship that might have allowed this problem to develop.

Good luck to you.   TRH

What therapy plan should I use while doing manual penis stretching technique?

Hello Dr. Herazy,

I was reading on the PDI website about the manual penis stretching technique for men with PD. What is the nutrition therapy plan that should be used with the stretching technique? If you remembered I had ordered Neprinol but I am unable to take it. So I would be very concerned about this nutrition therapy plan.



There is no specific nutritional therapy plan to be used while conducting the gentle manual stretching method.  All PDI therapy is intended to be used as part of a wide and diverse group of therapies.  The larger and well balanced your Peyronies treatment, the more synergy you will develop to support healing to occur; your stretching is just part of this effort and should not be seen as the major component of your recovery effort.   You might wish to review the contents of a PDI large plan as a good example of what you might consider doing to help yourself recover from your PD.   TRH

Question about phimosis

I have a problem in my penis . It is closed from my birth and cap has never came out. I am 17 year old.


You have a condition called phimosis, in which the prepuce or foreskin cannot be rolled back or retracted behind the glans or head of the penis in an uncircumcised male.     

Please talk to your parents or an adult to trust and seek medical care for this problem.   TRH

How long does it normally take for the body to heal Peyronie’s disease if it happens natually?


You mentioned, as well as others in articles I've researched elsewhere, that sometimes 50% of cases of Peyronies will go away by themselves. If this occurs what is the time table in which this will happen after you first get signs of Peyronies.  Thanks.



It is estimated that about half of the cases of Peyronie's disease that begin will self-heal or spontaneously resolve by the body healing the injury and removing the plaque within the first 12-18 months after the condition starts.   After 18 months the Peyronie's plaque tends to be permanent unless you undergo special and deliberate efforts to support healing to occur.  Since there is no way to document this number by the nature of self-healing that occurs outside of formal treatment, the number is at best an approximation.  

The fact that Peyronie's heals at all without active medical treatment means that the condition is not as hopeless as the average medical doctor will tell his or her patient.  The fact that about half of cases resolve on their own suggests the problem is correctable with minimal intervention and without drugs.  For additional information about supporting and encouraging natural healing with Alternative Medicine see  "Start Peyronie's treatment."   TRH      

What can I do if my Peyronies was caused by Tri-Mix ED injections?

Hi Doc… I have been using tri-mix injections for the past 12 years for erection problems.  The injections have been a perfect solution for the ED however about a year ago I realized I had hourglass Peyronie’s at the base of my penis near the injection sites.

I’m not sure if the injections caused they Peyronie’s disease but I have stopped using the injections and have been using a mechanical penis stretcher for the past 4 months but it hasn’t helped much if at all… Right now my penis is severely dented at the base on the left side.. It is about as half as thick there as it used to be at the worst part and looks like someone took a huge bite out of it there.

If my Peyronies was caused by ED injections would that be reversible and what would be the best course of action to address my Peyronies?

Thanks in advance for your time.



Twelve years of injections into the penis is a lot of injections.  I do not know how you can say that the Tri-Mix injections were a “perfect solution” for your ED if they might have caused your Peyronie’s disease.   That is a terribly high price to pay when there are so many other less dangerous and less offensive options to use for ED. 

Now you have been using for four months a mechanical penis stretcher that can also cause Peyronies.   You are really beating up this tissue that you wish to be healthy.  The penis stretcher will not work to eliminate the fibrous tissue because only the normal and healthy tissue will stretch while the dense fibrous tissue will resist the stretching force.  Simple physics says it cannot work.

You should be doing all you can to assist your body to heal the damage you have done to yourself.  I suggest you read “Start Peyronies Treatment.”

I have Peyronie’s disease and cannot develop an erection, what can I do?

Hi Dr, I have been to a GP and was told i have Peyronies. My penis curves to the left but I cannot have a erection and feeling in my penis is just about null. What do i do to get an erection so at least intercourse is possible ?



Greetings D,

There are many reasons a man might not be able to develop an erection.  Penis erection is a complicated process and many things can affect it.  To keep this discussion from being a three hour email, I will limit my response only to the single issue of Peyronie's disease as it relates to ED (erectile dysfunction) or the inability to develop an erection.

During the cold winter months I like to warm up the bathroom before taking a shower.  To warm the room I will turn on a small portable electric heater in the bathroom 30  minutes before showering to bring the temperature up to a toasty temperature.  Sometimes I forget to completely close the door to the bathroom, and this prevents the heat from being trapped in the room.  If I leave the door open just a little, only a little heat collects in the room; if I leave the door wide open, no heat collects in the room.  Most of the time when I make this mistake my wife will close the door for me (after reminding me I made that mistake again), and I will give her a big hug.  But when she does not notice the heater running with the door open I will have take a shower in a room that is cooler than I like.

That little heater does a great job of heating the room if the door is closed.  Closing the door is part of the process of trapping the heat that is created.   In a way, the door is more important to the room warming up than is the heater because the heater could run all day long with the door open and it never would warm the room.

A similar mechanism happens in the penis to develop an erection.  Blood is continually being pumped to all parts of the body, sometimes more and sometimes less depending on activity and needs of the body, but all parts of the body have a continual supply of fresh blood.  The penis has a much different kind of blood vessel arrangement than other parts of the body because it can almost immediately trap the blood that is being pumped into it.  When this happens it is like the bathroom with the door closed, or like a balloon that has been tied off.   

When Peyronie's disease happens, a mass of fibrous tissue called a plaque or scar develops within the layer of the penis known as the tunica albuginea.  This scar is not supposed to be there; it is not a normal thing, and the fact that it is there within the tunica albuginea very often makes it difficult or impossible for the veins of the penis to trap blood.  You might say that the veins have valves within them, and the fibrous plaque prevents those valves from closing.   When the valves do not close, the blood is not trapped and no internal pressure is built up that is associated with an erection.   This inability to close the valves of the veins might affect just a small part, or a large part, or all of the penis, causing a small, large or the entire penis to be soft or not erect.

The solution for this problem is not to pump your body full of drugs to make an artificial and temporary erection, because this does nothing for what is really wrong with you (plaque in the tunica albuginea) and it might cause other health problems as a side effect.  The solution is to eliminate, if possible and as much as possible, the plaque that prevents the valves from closing that causes the penis to be soft or flaccid (not erect). 

To learn how to help your body eliminate the Peyronie's plaque or scar please review the information at "Start Peyronies treatment."   TRH

What evidence do you have that this Peyronie’s treatment concept is effective?

If as you say 50% of men self heal from peyronies disease, what empirical evidence do you have that any of your treatments are actually effective? Testimonials of cures are to be expected in any group of men whether they take your medication or a placebo. What evidence do you have that your medication is better than a placebo?



Thank you for your valuable and interesting question.

Empirical evidence is taken from or by way of naturalistic experience or observation, as well direct experimental procedures.  It serves to defy or support a scientific theory or a working hypothesis that is under study.

For those who have spent any time reading the PDI website, you know that I have repeatedly reported that at this time it is not possible for me to conduct research or scientific investigation as is conducted by the government, large universities, medical research hospitals or pharmaceutical companies. I do the best I can under the circumstances I work under.  I am limited to the reports and communication about success and failure I receive from men who choose to follow the PDI concept of Peyronie's treatment.  This information is provided to me on a volunteer basis by men during their self-directed treatment, so it is understood that I do not have any way to control how each plan is conducted or to verify the accuracy of the information that is received.  

When early medical research was done with natural therapies like vitamin E, or acetyl-L-carnitine, or PABA, or quercetin, on Peyronie's disease the effects were often positive.   You can read these early reports in which all of these were found to have positive effects to reduce the Peyronies plaque or reduce advancement of penile distortion.  They all seem to end with the comment that would go something like, "Further investigation should be done based on these positive outcomes to verify these results."   Of course, since there is no profit or advantage in a drug company testing a common nutrient, no further testing is ever done.  No one is interested in the results of combining natural enzymes, vitamins, minerals, and performing gentle manual stretching because these ideas represent no business opportunity.

From the information I have gathered over the last 10 years while working with men who have Peyronies, I estimate that about half of these men have had their Peyronie's disease for 18 months or less, and the other half have had their Peyronie's disease for more than 18 months (many start their PDI-based treatment with a history of Peyronie's disease of five years duration, and a few have had their problem for 10 years or more).   Based on my feedback from these men, there does not seem to be much difference in the rate or degree of improvement between these two groups, or in the types of problems or difficulties they encounter while under care.   It seems that the body is able to heal or correct a newer (18 months or less) case of PD about as easily as an older (18 months or more) case of PD.   This 18-month time reference point is important because it is rather commonly maintained that any case of PD that will spontaneously heal or self-correct will do so before the 18th month; after 18 months the PD is considered permanent.  This is the reason so many surgeons will wait until a case of Peyronie's disease has reached the 18 month mark, since at this time the condition is thought to be stable and permanent.  

When I worked to develop the treatment plan that eventually became the PDI concept of Peyronies treatment I had my PD for about 18 months.  Many men who report back to me their positive results have had their problem for 2-4-6 years or more.  All of these cases are considered permanent and stable by medical standards.  Any change or reversal of the size, shape, density or surface features of  their PD scar mass or change in their deformed or curved penis would have to be considered clinically significant.  

At this time I am not interested in conducting blind studies with placebos with men who have Peyronies.   After 10 years of work I am at a point where I still improving and expanding the PDI treatment protocol.  It would be wrong for me to conduct research in this way that would deny every man the opportunity to reverse his problem.  Keep in mind that I am not attempting to make pigs fly; the PDI concept is really not all that extraordinary or extreme.  All we are attempting to do is to increase or support the natural ability of the body to heal and repair PD that tends to occur in about 50% of the men who develop this condition.  For many men who take the time to read the information on this website the idea of natural healing makes sense.   I suppose it all comes down to the question of, "Do you think it is possible to help the body heal if you improve your nutrition and do a few common sense things that assist the process of recovery like tissue detoxification, simple stretching and increase of blood flow?"  

You are viewing this work while it is its early stages, as the men are told when they read the PDI website.   Testimonials and personal communication is what many medical ideas have developed from in the past.  You are seeing this idea at that stage of development.  I do not know if that should be a reason for condemnation of this work.  Many men who need treatment for Peyronies disease understand the basic concept of supporting the ability to heal and repair and give the process a try.  Many who do it well find good results.

I completely understand your concern and interest in evidence of treatment efficacy, and comparison to placebo response.   However, keep in mind that all the glowing praise and approval for a drug that passes through government, university, medical research hospital, or pharmaceutical company research is no guarantee of effectiveness or safety of those same drugs or procedures.  So much of the kind of proof that you ask about seems to make very little difference to the people who use those approved drugs in the real world.  So many of the drugs that pass through rigorous research tests, and perform so much better than placebos, only come to fail to get results with actual patients or are found to be dangerous because of the side-effects and dangerous complications they cause. 

Again, thank you for the opportunity to explore and discuss this question.  Perhaps in time this idea will be taken up by a large research group when I have gathered more evidence and weight of public opinion.   TRH

Is it safe to take Neprinol with medication?

hello my name is kathy ! i am 44 yrs old and had two heart attacks and open heart surgery four years a go and i take fish oil and 325asprin and metoprolol 25 mg but i take half of a pill.is it safe to take neprinol afd with my medications . thank you kathy

Greetings Kathy,

Please discuss this question with the physician who prescribed your various medications.  In my opinion there would be value in your taking Neprinol, but you must monitor your blood clotting rate while you balance your intake with the drugs.  However, you need to have this issue completely regulated by your treating doctor before you make any changes or additions to what you are now taking.   Good luck to you.  TRH

Is there a connection between using Cialis and Peyronies disease?

Is there a connection between using Cialis and Peyronies disease? The reason being is because I had no signs of the disease developing. I woke up one morning to find the scar/plaque on my penis when I went to the bathroom. Overall I took about 13 pills over 6-7 weeks, only taking one at a time. My doctor examined me and confirmed that I have it but did not offer anything solutions or why it happened. He did say he was surprised that it just came on as fast as it did which was like overnight for me.  I know my body and I was completely surprised.


Cialis is a member of group of drugs called PDE5 inhibitors, used to treat symptoms of erectile dysfunction (ED). Other members are Viagra and Levitra.

Yes, there definitely appears to be a connection between using Cialis and Peyronies disease.   Over the years I have encountered many men whose Peyronie's disease started after using just one dose of a PDE5 inhibitor.  There are many lawsuits pending in this regard.

Here are a few of the posts I have written about this subject over the years: Peyronie's disease plaque, Viagra, Cialis, Levitra and blood supply, and Peyronie's disease treatment and Viagra, Cialis and Levitra; there are others if you look further on the website.  TRH

Starting to lose hope about Peyronie’s disease

Hello Dr. I'm inspired to read through these posts that your actually spend time with the people on this site. I'm wondering how I go about getting a phone consult with you? I am 46 years old and have experienced a curved penis and diagnosed with Peyronies about 2 years ago. It seems to be getting worse by adding pain and trouble keeping hard during sex. Orgasms are not nearly as intense and I'm not able to 'adapt' for my wife like i could even 6 months ago.

I'm skeptical like many of the men on this forum, but they seem very satisfied that you take the time and attention, and I'm starting to lose hope so i thought i'd reach out.

Thank you

Franklin, TN


Greetings Don,

I remember what it was like when I had Peyronie's disease, so it is easy for me to want to help. 

Your skepticism is related to the medical sites who do not know anything about natural Peyronie's disease treatment, have never used it, have never tried to learn anything about it, and yet say it cannot be done.  All we are attempting to do is to increase the odds for natural  healing of PD as it occurs in half of the men who develop this problem.  We are not trying to make pigs fly.  It happens for half of the men who get PD, with a little help why not you?

If you want to schedule some time on the phone to discuss your situation, just scroll down a short distance to look for the picture of me holding a telephone and purchase a small block of telephone time.  I will email you to arrange for a time to discuss your situation.   TRH

How many units of vitamin E should I take for my Peyronies?


After reading much of the literature on Vitamin E treatment I find it hard to conclude how many IU’s of the vitamin one needs to take on daily basis ??



Greetings Dave,

With the naturally occurring and full spectrum vitamin E that is available on the PDI website there is much less cause for concern than when the synthetic forms of vitamin E are used.  All the nasty reports of bad reactions to vitamin E involved the use of synthetic vitamin E.

It is best to keep your daily dosage down to around 1200 IU of vitamin E when used in conjunction with a larger plan of diversified therapies.   When you place your order with PDI for any therapy products you will be given complete and detailed information how to use whatever you order.  TRH

What is your recommendation for a Peyronie’s disease treatment?

I have had Peyronies for about 1 1/2 years. It has now progressed to the point where my penis bends down from the base at a 60 degree angle when erect. My sex life has essentially come to a screeching halt.  I would like a recommendation of treatments that I should incorporate.


Greetings Bruce,

The PDI website is loaded with information about how you can go about using Alternative Medicine to increase your ability to heal and repair your Peyronie's disease; all you have to do is look and read.  I suggest you begin reading at Start Peyronies Disease Treatment.

I also suggest that start with the largest and most aggressive plan you can sustain for about three months to determine if your Peyronie's problem will respond to this form of treatment.  Sample plans are shown on the Peyronie's Disease Institute storefront. 

Sex problems are common when a curved penis prevents entry.   You should look at this book for help, "Peyronie's Disease and Sex."   TRH

More questions about Peyronie’s disease and a congenitally curved penis

Hello Dr Herazy,

I posted the congenital vs Peyronies curvature question that you recently answered. Thank you for your in depth answer but I have a couple follow ups regarding one of your response.

You said you've had a number of congenitally curved men that have improved with the manual stretching + enzymes… if there is no scar tissue in the congenital penis curve, and it is instead caused by two differing sizes of the corpora cavernosa chambers, then how do these stretching + enzymes work? What are those therapies actually doing to help straighten the penis? Since they're obviously not helping to break down any scar tissue as there's none there in the first place as with a congenital curve.

The whole pd vs congenital thing is still quite confusing & nebulous to me. Yes, I can recall a curve even as a young child, which points to congenital. A downward curve, like mine, seems to be fairly common among congenital as well. But at the same time my erections have firmed up due to the manual stretching and the curve seems to improve almost daily with the PDI method of penis stretching. Which seems more related to Peyronie's disease. I'm not sure how that would happen if it were congenital unless I'm somehow stretching not scar tissue but the actual corpora cavernosa chambers.

Also, the congenital improvements reported to you. Are the improvements they report mild, small? Is improvement common, rare? Comparable to the more successful PD responses that seem to be quite common with the PDI therapies? And it's that you simply haven't had a large enough sample of men with a congenitally curved penis to use the treatments to say definitively whether they work for them or not as a whole? Any indication they show more difficult to correct than a PD distortion?

Lots of questions, I know. But I think it's important that people in my position have as much info as they can.

Thank you.



Greetings again A,

Thank you for your thoughtful follow up questions.

Living tissue (animal or plant) is rather plastic, meaning its shape can be changed within certain limits – the tree that grows around and engulfs the barbed wire fence, African native women who compress their shoulders by forcing them down with brass rings around her neck, young Japanese girls whose feet are compressed by tight binding, ancient Mongolian warriors whose foreheads were flattened to look fierce and warlike, the contortionist whose joints are made preternaturally flexible, even I suppose the old joke about the cowboy whose legs eventually become bow-legged in response to years of riding a horse.  We see around us evidence that otherwise normal tissue can and does change its shape when gentle force is applied over a long time.

It does not take a great amount of imagination to envision also altering and equalizing the small size discrepancy that exists between the right and left corpora cavernosae in men with a simple congenital penile curvature, making it straighter by reducing the internal asymmetry.   Time, persistence and a light touch that does not provoke innate resistance to change is all that are needed.  These changes take place using the PDI process of using gentle manual stretching simply because the method is based on so many examples that occur in nature around us.

My theory is that the systemic enzymes assist the tissue remodeling that occurs during the gentle penis stretching process.  The manual stretching initiates a signal to the brain to change the tissue in question on a cellular level.   The fibrinolytic enzymes on the PDI website would assist that process by remodeling the fibrin of the soft tissue layers as they are being gently stretched.    Keep in mind that tissue remodeling goes on after each and every wound and injury you sustain.  The body is engineered to remodel tissue as part of the healing process.  All you are doing with the PDI technique I present is to gently focus that process to your curved penis.

You ask about “small’ or “mild” curves.  What exactly is your definition of a small curve?  Any man who tells me his curve is small or large, mild or severe, is taken with a grain of salt because what do these terms mean?   What would be a small curve to one man could easily be a large curve to another.  This is part of the difficulty in communicating with people through the written word.  Trying to be as accurate and objective as possible, I usually ask the men I work with for a description of their congenital curve this way: Is your penis curved less than, more than, or about the same as, the average banana?   The answer I am given provides a fairly good idea of what we are dealing with.  For your information, the great majority of men who I work with say their congenitally curved penis is about like a banana.  A few say less, rarely more.

Men do not offer reports frequently or well, offering very limited information about their condition or progress.  I spend a lot of time giving information to men, and receiving only a small amount of information from them in return.   The reports I receive back could be called seldom or rare, and are often limited to “my curve is gone,” "it’s really a lot better,” or “after a few weeks my bend is maybe half gone.”  The terms are almost always broad, general, and not as detailed as I would like them to be.  When I ask for further clarification or details, I seldom receive a reply.  Most of the time when I hear back from a man to whom I provide help, it is to say that there has been improvement; rarely do I hear that the problem did not improve at least to some degree.  Women will tell you that men do not discuss this problem of a bent penis very much; I know this is true.  I think that when a man gets this problem, shall we say “straightened out,” he wants to forget about it and put it far behind him.  The last thing he wants to do is discuss his previous deformity in detail.  TRH

How can I tell the difference between Peyronie’s disease and a congenitally curved penis?

Dr Herazy,

I do not know if I my curvature is PD related or congenital. What are some of the signs that point to a congenital curve versus a PD distortion? It's frustrating because my condition seems to exhibit signs of both congenital and PD. I'm sure seeing a urologist is required to say for sure but even then apparently some will misdiagnose simply because they can't find the scar tissue present in PD. So, even that avenue doesn't seem to be a sure fire way of knowing 100%.

We know that PD is caused by an excess of scar tissue buildup in the tunica albuginea due to physical trauma to that area. But what causes the distortion in the congenital curvature? Is it an excess of scar tissue one is "born with"? If not, what would cause a penis to curve in dramatic fashion (35º- 45º downward) w/o scar buildup? To me that would seem to be an exceedingly rare condition to be born with. I could see a 5º, even 10º curve but 45º is a heck of a curve to be born with. If a congenital curve has no scar tissue, how do the PDI therapies treat it in that case since there would be no scar tissue to heal?

Secondly, if one does have a congenital curve, does the treatment for it change in any way from that of a PD distortion? How successful are your PD therapies at treating congenital curvature and do you even intend on doing a full study on this?

As you can tell, not knowing for certain whether my curvature is PD or congenital, I have quite a few questions regarding the both of them. Please help me make sense of the differences and their subsequent treatment.

Thank you.



Thank you for the great question. 

Probably the answer to your question is found with the easiest and most fundamental observation that you can make.   The basic difference between a penis that is bent due to Peyronie's disease and one that is congenitally curved penis is time.  When did you first notice that your penis is not straight?  

If you have always noticed, even as a young boy, that your erect penis is bent then you probably have a congenital curvature of the penis

If you have only recently noticed that your previously straight (or almost straight) erect penis is suddenly curved or distorted in some way, then you probably have a bent penis due to Peyronie's plaque that has altered the ability of penis to expand fully.

Usually, a congenital penis curvature is not accompanied by pain, while a recent case of Peyronie's disease can be painful.   Further, a congenital penis curvature is not accompanied by a palpable nodule or mass of fibrous tissue, while a recent case of Peyronie's disease will demonstrate plaque formation.  This plaque formation is not always easily located, so it can be deceptive to make a diagnosis of PD based solely on the ability to locate this foreign tissue.

In congenital curvature there is no scar material in the shaft.  The curvature in this case is simply due to corpora cavernosa chambers that are not of equal size or dimensions.   Just like you might have ears that are not the same size or shape, or large toes, or thumbs, the body is not always symmetrical.   

I do not have a lot of information about congenital curvature responding to the PDI treatment protocol because men simply do not report this kind of information back to me.  I can tell you that over the years I have a number of men say that the gentle manual penis stretching technique coupled with a good dose of systemic enzymes like Neprinol made a difference with their congenitally bent penis.  TRH

How does jelqing work on Peyronies disease plaque?

How does jelqing exercise work on peyronies disease plaque?  Does this exercise soften the plaque or harden it?


Jelqing can injure the penis because it is not so much an exercise, but a series of aggressive penis stretching and maneuvers that force blood under great pressure into penile tissue.  It cannot soften the Peyronies disease plaque, but can easily cause more plaque to develop because the tremendous squeezing and stretching force that are required in jelqing will literally tear the internal tissue of the penis like the delicate tunica albuginea.  This repeated and forceful stretching of tissue by jelqing goes beyond the normal tissue limit and causes the delicate tissues to become damaged far more than it causes it to actually stretch.

Overall, jelqing is a bad idea because it is dangerous.   The trauma to the delicate tunica of the penis caused by jelqing is probably enough in some men to start the injury that results in the excessive scarring that is known as Peyronie's disease.  Over the years I have spoken to many men who are convinced their Peyronie's disease started after just one session of jelqing.

One of the most common reasons that men say they do jelqing when they have Peyronies disease – besides their effort to enlarge the penis – is to increase the blood circulation.   Do you jelq your hands if they are cold, trying to make more blood to enter?  Do you jelq your arms too?  How about jelqing your feet when they do not have enough blood.  No, no one does that.   The body does not need to be jelqed to increase circulation.  Before touching your penis to jelq it, is it cold, is it blue?  No.   Then the circulation going into the penis is not the problem in Peyronies disease.   The problem is that the blood is not being trapped by the corporal veins to create the greater fluid pressure that results in an erection.  The problem of a weak erection in Peyronie's disease is caused by veins that do not trap blood and this happens because of the presence of the Peyronies plaque.   That is where you need to concentrate your effort.   You need to improve the ability of your veins to close by eliminating the PD scar or plaque.   Jelqing does not do this – and probably injures that ability since you are using such great forces that the valves can be damaged.  Proceed at your own risk.