New Customer – how to select your best treatment plan

Suggestions to help you decide how to start Peyronie’s self-treatment

Read these descriptions.  Decide which description is closest to your personal situation.  You can use any level of treatment you wish, but keep in mind that a more aggressive approach might give you better results.  

Small Peyronie’s treatment plan:


PD less than 12 months
Mild to moderate curved penis

Under 25 years old

Generally good health

No to little problem with intercourse

No to little use of Viagra, Cialis, Levitra, statin drugs for cholesterol, or Propecia

Medium Peyronie’s treatment plan:

PD between 12-24 months
Mild to moderate curved penis

Any age

Generally good health

Mild, moderate or occasional problem with intercourse

Moderate to heavy use of Viagra, Cialis, Levitra, statin cholesterol drugs, or Propecia

Large Peyronie’s treatment plan:

PD longer than 24 months
Moderate to severe curved penis or bottleneck or hourglass deformity of any degree

Over 60 years old

Generally poor health or complicated medical history

Moderate to severe problem with intercourse, or ED that prevents intercourse

Moderate to heavy use of Viagra, Cialis, Levitra, statin cholesterol drugs, or Propecia

60 thoughts on “New Customer – how to select your best treatment plan

  1. mike brophy says:

    had nesbit procedure for peyronie’s disease 80 degree curvature 4 years ago,since then I have pain around middle of penis shaft when erect.understand that penis has straightened but plaque still there causing the pain. is it too late to start one of your treatment plans for my peyronie’s disease?

  2. David says:

    Hi, I am over 60,had this for over two years, never used viagra or other such drugs, but I am on medication for high BP. I presume that I need the Large Plan, but will it cause any BP issues?

  3. Dr.Herazy says:

    Greetings David,

    I have been doing this work with Peyronie’s disease and Dupuytren’s contracture since 2002. In that time I have not received any report or complaint that elevated blood pressure was aggravated or caused by using the PDI plans. This assumes that you are going to use the plan as suggested in the notes and instructions you receive with your order.

  4. Kalim says:

    If i star medicine it is for whole life or it will cure peyronie’s disease.. Or i have continue take medicine I am 35 year old..I have reaction have no problem with sex but I have my penis nerve bent on left penile..some time I am getting pain before urine..

  5. Dr.Herazy says:

    Greetings Norman,

    You are not the first to ask this question about sulfa drugs and Peyronie’s disease treatment; it comes up more often than you would imagine.

    Our MSM (Methyl Sulfonyl Methane), also called Fundamental Sulfur, is the only sulfur containing therapy produce we use for Peyronie’s disease treatment. In over 14 years of working with MSM I have never been told of a problem from thousands and thousands of users. Perhaps because of the way the sulfur is combined within the formula it is metabolized better than the drug form of sulfur. If you are concerned I would suggest starting out MSM with a single dose for a few days and then slowly proceed from there if that low dose results in no problems. Your Peyronie’s disease treatment should proceed well from there. TRH

  6. Dr.Herazy says:

    Greetings Kalim,

    Peyronie’s disease treatment does not have to continue a lifetime. Most people do go on for a few months after their problem goes away or is improved as far as they want to go. TRH

  7. Rafael Mayorga says:

    I live outside the U.S..
    Can you mail the treatment to Central América?
    I have a visa to travel to the U.S. and go there sometimes.for business or to visit friends. I’d like to know wich one is the best treatment for me. I am 58 and had peyronie about two and half years. And also I’d like to get all the medications for at least 4 to six months..Or for the shortest time you would recomend to take the treatment.

  8. Loree Starr*Brown says:

    Very interesting info! I will be ordering for my husband’s Peyronie’s disease—-but, I’m a woman with lifelong show of celiac disease & many other lovelies coming in under its umbrella….fibromyalgia, systemic lupus, scleroderma, etc,etc,etc…..could the plan help me with some of these?

  9. Dr.Herazy says:

    Greetings Loree Starr,

    My daughter’s middle name is also Starr. and also with a double RR. You folks are really rare and very special.

    I have had many men who have faithfully and aggressively followed a PDI program, who later reported not only an improvement in their primary Peyronie’s disease but also improvement in a myriad of other concurrent health problems. When I was treating my own Peyronie’s disease I also noted several diverse and unrelated conditions (gray hair, GI complaints, thin brittle fingernails, stamina, insomnia) also take a turn toward normalization. It appears that there is no way to predict who is going to respond or which secondary complaints will improve; they just do. I welcome you to tag along with your husband’s Peyronie’s disease therapy program to see what might happen in your case. TRH

  10. Dr.Herazy says:

    Greetings Pete,

    It’s good that you are interested in the DMSO treatment for your Peyronie’s disease because it is intended to directly work with the internal PD scar when applied directly over the scar because of its ability to penetrate the tissue from the exterior. It will itself soften the scar tissue directly, as well as transport the copper peptide and vitamin E that are applied at the same time.

    However, DMSO is not best used by itself as a solo treatment; it is best used in combination with other internal and external therapies. If you use DMSO as a solo Peyronie’s disease therapy it will likely not get the kind of results with PD as you are hoping to see. Peyronie’s disease is a stubborn and complex problem to treat and from experience I have learned that the more broad-based and aggressive your treatment is, the better the result’s will be. Many people try to use DMSO by itself because it makes sense and they like the fact that it is applied directly to where their problem is located, right over the Peyronie’s disease scar tissue, but later add other combinations of internal and external therapies to what they are using because a larger effort is needed to support tissue changes. This results in lost time and actually a larger expense in the long run. The Peyronie’s Disease Institute encourages these particular plans because they have been shown to often get results when nothing else does. TRH

  11. Dr.Herazy says:

    Hola Rafael,

    Yes. We send all over the world. Not often to Central America, but it does happen.

    There is no way to know for sure ahead of time what is going to be the best Peyronie’s disease treatment for anyone. The best advice I can offer is do as much as you possibly can to give your tissue the greatest opportunity to respond to your Peyronie’s disease. Half-hearted efforts are usually disappointing. The shortest time to determine if your tissue is going to respond to what you are doing is about four, maybe five, months. TRH

  12. Dr.Herazy says:

    Greetings Delwar,

    A larger and more diverse Peyronie’s disease treatment plan when well executed and applied faithfully tends to be more successful than a small plan with a narrow focus that is also well executed and used faithfully. The body usually needs help to recover from Peyronie’s disease, and a larger plan supplies a more broad layer of nutrients and strategies to supply that help. TRH

  13. Dr.Herazy says:

    Greetings Mike,

    Constant or very frequent pain after a Nesbit surgery to correct Peyronie’s disease is common. You are fortunate to have some degree of curvature reduction because so many of them do not improve curvature very much, and can also leave the penile shaft weakened and unstable making penetration difficult or impossible. You did not mention losing much penis size as a result of the Nesbit, so I hope this means your loss was minimal. I mention this because you should be grateful for whatever progress you have earned in spite of the continued pain.

    PDI Alternative Medicine treatment can still help reduce your remaining plaque, but not as well as if you never had the surgery; prior surgery complicates eventual recovery because it causes additional scar tissue to develop. Alt Med can still be used to assist the natural healing process, but you have to be prepared to do more work and take longer for improvement to occur. TRH Peyronie’s disease

  14. Gary says:

    I am 64 and have developed slight curvature last 4 months probably due to aggressive intercourse that I fear might be Peyronie’s disease. It’s very upsetting to me to see this and just started manually gentle stretching to the area along with some heat. Is this OK and what would be the next step? No improvement thus far and I am in excellent health. Taking no meds with cholesterol of 179.

  15. Kimrajh Ramoutar says:

    I have Peyronie’s disease just over two years now and I have been using POTOBA and Vitamin E which were prescribed by my Urologist. I have seen results but I cannot extend properly and the curvature is downwards and hardening along part of the shaft. I do not take any type of medication. I suppose a medium or large Peyronie’s disease treatment plan may work for me.

  16. Dr.Herazy says:

    Greetings Gary,

    First, please get yourself checked out by a urologist to determine if you have Peyronie’s disease. What you are doing is not wrong, although I have never gotten a report from anyone who has used only heat and manual stretching to reduce or eliminate Peyronie’s disease. What you are doing thus far is a good effort, and certainly in the right direction, but if you in fact have Peyronie’s disease you want to do more than what you are currently doing.

    I think the next step is to go to the PDI website homepage and familiarize yourself with the Alt Med self-treatment ideas that are available to you. Use the page to help you organize your thinking if it turns out you have Peyronie’s disease. Some men do not use one of these PDI plans, they put together their own plan based on what makes sense to them and the thinking of their MD. However you go about making that decision it is important to try to assist your body’s healing ability with a broad and diverse range of therapies. Peyronie’s disease is a tenacious problem that does not seem to respond to minimal or isolated effort; diverse and aggressive Alt Med treatment has shown to provide the best results. Let me know if I can help you along the way. Good luck to you. TRH

  17. Dr.Herazy says:

    Greetings Raj,

    There is no way to know ahead of time what Peyronie’s disease plan or which particular therapy items you will respond to, or what dosages might be indicated in your case. At this point of development of our work we do not know how to be specific in Alt Med treatment for Peyronie’s disease. Since we have a very good idea of the wide range of therapy items that can help men with Peyronie’s disease we suggest they use as many of them as possible to get the best results possible. This is why we always recommend that a man uses the largest plan he can afford to use for at least 3-4 months as he attempts to support and encourage his body to heal the Peyronie’s disease fibrous tissue. Either one, the medium or large treatment plan, have been used by many hundreds of men for their Peyronie’s disease with good results.

    As it sometimes happens a man will get small or partial reduction of his Peyronie’s disease scar using a medium or large plan, and will have to experiment with dosages of those therapy items and perhaps remove 1-2 therapy items and add 1-2 new therapy items into his plan to encourage further fibrous tissue reduction. Usually this is not needed, but in some cases it is necessary to experiment with those therapy items that are used to get best Peyronie’s disease results. I can offer ideas and suggestions with your plan should this be necessary. Good luck to you. TRH

  18. Dr.Herazy says:

    Greetings Bahadar,

    There is no single cream or therapy product that works by itself to treat Peyronie’s disease. It would be wonderful if it was that easy.

    Peyronie’s disease is a difficult and stubborn problem to treat. The best approach we have found is to use several different kinds of treatment both inside the body and outside directly to the area to help your body heal. Please look over the website to learn how this can be done.

    If there is a cream product in your country that can you believe is helpful to treat Peyronie’s disease I would like to hear about it from you. Thank you. TRH

  19. Dr.Herazy says:

    Greetings Bruno,

    Peyronie’s disease can give a man a penile distortion, like a waist band effect, or a bottle neck deformity, curves, dents, twists and combinations of all these. Each one is caused by the presence of abnormal fibrous tissue within the deeper layers of penis. The distortion is the thing that gets your attention about Peyronie’s disease, but the distortion is not really the problem; the real problem is the mass of fibrous tissue below the skin that causes the penis to be misshapen.

    So when you ask if ultrasound treatment can help the waist band (also called an hourglass deformity) of Peyronie’s disease, the answer is a qualified yes. The yes answer is qualified because I do not want you to think that ultrasound by itself can help reduce the Peyronie’s disease scar tissue. In my experience, no Alt Med treatment when used by itself has much, if any, helpful effect on PD. But we have seen hundreds of cases improve, ranging from minor to major to complete relief, when a man uses a broad and diverse Alt Med program that can support or assist his body to get rid of the fibrous tissue. Keep in mind that half of Peyronie’s disease cases clear up on their own without treatment because the body naturally eliminates the fibrous material though the immune system. All we are attempting to do is to help your body with that natural recovery by supplying all the help possible so it can get the job done; this is why small or partial help does not seem to get good results. To support and encourage this natural healing response the body seems to need a broad assortment of vitamins, mineral and enzymes (plus ultrasound at times) to get the job done.

    PDI did a research project several years ago that indicated Alt Med Peyronie’s disease treatment results were improved or increased in previously stalled treatment programs when 3Mhz ultrasound therapy was added to those plans, while all other treatment remained the same; adding ultrasound to a poor plan boosted the results. We did not test or research using ultrasound by itself because that research was done previously and found to not be ineffective, but we found ultrasound had some beneficial effect when used in combination with other therapies. This is the point I want you to understand in regard how you treat your Peyronie’s disease.

    I have had several men try to use ultrasound by itself for their Peyronie’s disease and it did not do much good. Later they added a broad and diverse group of Alt Med to their use of ultrasound and they saw their scars get smaller, softer and less well defined, indicating that the body was absorbing the fibrous material of their PD. Once the scar is gone the penile distortion goes away because there is nothing below the surface to cause a deformity.

    I hope this helps you decide how to approach your Peyronie’s disease. TRH

  20. Ravi says:

    I got peyronie’s disease curve penis when I am 16 years old. It is left side curve and painfully also now I am 20 years. I am from Nepal. how I can make my penis straight. how I can cure my left curve penis by massage. give me good idea.

  21. Dr.Herazy says:

    Greetings Ravi,

    The good idea I can give you is to read the PDI website, and learn how to help your body get rid of the Peyronie’s disease problem naturally.

    Your curved penis can be helped by eliminating the fibrous scar material, located inside the penis, that is making it now bent. We believe the best way to do that is to help your body get rid of that fibrous scar material naturally, as happens with the 50% of men whose Peyronie’s disease goes away by self-healing. The PDI method works to assist and support the ability of the body to self-heal and eliminate that scar tissue.

    I do not know of any way to cure your Peyronie’s disease by massage. However, PDI developed a gentle manual stretching technique that can be used as part of a larger Peyronie’s disease treatment plan that is often helpful. This method can be learned from the DVD that is available at

    There are no simple or easy answers for Peyronie’s disease; all require hard work and time. Good luck to you. TRH

  22. Mikkel Emil Dahlgaard says:


    I am 24 years old and got Peyronie’s disease just over a week ago – the symptoms are very clear, meaning there’s a definite swelling and infection in the sene and there’s small but significant pain while erected. There’s no curvature yet and i am quite confident as i’ve figured it out so soon.
    My question is: what will you reccommend for best treatment when i’ve found out so early and since i’m going on a backpacking trip for half a year in two weeks – how much do you suggest i bring along for the journey?

    Thanks a bunch and your website has so far been very helpful in changing how i think about Peyronie’s disease – as all doctors in my country say there is absolutely nothing to do about it! 🙂

  23. Dr.Herazy says:

    Greetings Mikkel,

    You will have to explain what you mean by “sene,” since I do not recognize that term. Perhaps it means something in your native language.

    Swelling and infection are not associated with Peyronie’s disease. PD pain often occurs in either the erect or flaccid state, or both, but it can also be absent in some cases. You state that you believe you developed Peyronie’s disease over a week ago. Perhaps you are relating to an injury or trauma that occurred, and resulted in pain and swelling, as the start of what you call your Peyronie’s disease. Perhaps you are swollen, and have pain, and I will assume you had some traumatic event over a week ago, but even so it is my opinion that at this time you likely do not have Peyronie’s disease. For you to truly have PD you would have had to develop a fibrous plaque within the tunica albuginea of the penis, resulting in possible pain, possible penile distortion of some type, possible loss of penile size and possible alteration of erectile function, all within a week’s time. Usually a penile injury is immediately evident much in the same way that an injury to any part of the body would be evident, like a sprained ankle, but the actual tissue changes of Peyronie’s disease takes time to develop, usually several months.

    Again, if it was a penile injury that started all this, there is always the possibility that the tissue abuse can eventually evolve into Peyronie’s disease at a later time. For this reason it is important that you reduce the tissue inflammation as promptly as possible. To that end I suggest you do three things. First, that you treat the area to reduce tissue injury by ice pack applications several times a day for the next week or so, use some NSAID drugs such as aspirin or whatever you prefer, use some essential fatty acid supplements to get the inflammation down, and that you be most careful that you never injure your penis ever again. In regard to the latter, I also suggest that during this time you refrain from all sexual activity to avoid re-injury and speed healing. Second, pray to God that you do not develop Peyronie’s disease in your life. Third, that you have a great time on your six month backpacking trip. What a life! TRH

  24. Mikkel Emil Dahlgaard says:

    Hello again,

    Thanks for the in depths answers to my Peyronie’s disease questions. I certainly have not have all of the things you describe happen to me within the last week but I have though had as you call it a ‘traumatic experience’ where i got a little hurt.

    You seem to think that it could easily for now just be like a sprained ankle and just go into remission before it develops to Peyronies. I must admit that the pain has reduced itself to some degree during the the last week and the symptoms maybe also. I have no curvature yet ofc, but I have a tendon that is weirdly swollen/crooked-like and which is running from the penis root to almost at the head. Despite of that i have no significant pain anymore so as you said, i most definitely am praying that it’s not Peyronie’s disease!

    By a “sene” i meant a tendon and you were correct in assuming i had just put in a danish word- what a brain fart. Since I went to the doctors office i’ve been taking penicillin. would that do the trick? or would you recommend something else instead?

    Again thank you very much for your time and effort in this field!

    Best regards Mikkel

  25. Dr.Herazy says:

    Greetings Mikkel,

    So pleased to learn you looked into your Peyronie’s disease problem and are taking care of yourself. Good man. Some men act like children and avoid the issue.

    When your penis “got a little hurt” recently the inflammation and possible micro-trauma could have been taken care of sufficiently by the frequent cold packs, aspirin and avoidance of sexual activity I mentioned in my previous response. The small trauma you sustained is still an important issue to me. For this reason, in an attempt to avoid Peyronie’s disease, it is important to control and reduce any penile inflammation response that might still be evolving and developing over time because this is how Peyronie’s disease develops. Time will tell in your case. Apparently your doctor thinks you have an infection going on, more so than inflammation, as deduced by his prescription of the penicillin, only. He has examined you, so he knows best. However, since Peyronie’s disease is what I know best and you asked for my recommendation, I offer that it is worth the ounce of preventive action of cold packs and rest to avoid a pound of cure and a ton of anguish related to PD.

    Remember, you are Danish and for this reason you have a genetic predisposition to Peyronie’s disease. It is easier for you to develop PD than someone not so inclined.

    Not sure about the “tendon” you mention. Based on your brief description (“running from the penis root to almost at the head.”) it sounds like you might be referring to the urethra on the inferior or underside of the penis and within the corpora spongiosum, which in some men can protrude along its length, and can feel thickened and taut.

    Your English is beautiful and contemporary, very natural. You should be pleased and proud of your language skill.

    Only think of Peyronie’s disease again if there is reason to do so. Right now you do not have any reason for concern, but be aware. TRH.

  26. Skrillex says:

    Hi respective Dr.Herazy I had bottle neck/hourglass on my penis making me think I have Peyronie’s disease. A year before it was look slighlty curved But if I masturbate I can clearly observe that the plaque are more developing now my penis look somewhat bulged and the plaque surrounded my penis from top to bottom.So which plan do I need to take and After my treatment completion if I masturbate or having sex does the plaque forms again…Thanks In Advance

  27. Dr.Herazy says:

    Greeting Skrillex,

    I am not completely convinced you have Peyronie’s disease. It would be foolish to use the PDI treatment ideas if you do not actually have Peyronie’s disease.

    You report you first had a slightly curved penis and a year later it developed into a bottle neck/hourglass, which is only one part of having Peyronie’s disease. You do not mention any other common PD symptoms: pain, reduced penis size, reduced ability to become erect, or plaque lumps and bumps that are located below the surface of the penis skin (which only rarely can be seen from the surface). Usually PD plaque or scar tissue are so flat, so few, and so small and deep that they cannot be observed. You confuse me a little by stating your penis is bulged and that you can observe your plaque surrounding your penis from top to bottom. This is not typical of Peyronie’s disease. Your brief description gives the impression of either a massive number of huge PD plaques or scar tissue, or something else is happening in your case. Please go to your doctor to examine your problem for an accurate medical diagnosis.

    If it turns out you do have Peyronie’s disease, I suggest you use as large a plan as you can comfortably use and afford for 3-4 months while you follow the treatment suggestions that are provided with your first order. Plan selection or plan creation is not based on any particular set of symptoms or degree of involvement. Plans are used to increase your ability to reduce and eliminate the PD plaque and fibrous scar material, regardless of how large or small it might be, or how long you have had the problem. Lastly, in 15 years I have not received one report of Peyronie’s disease returning after successful PDI treatment; based on an absence of information saying otherwise, once Peyronie’s disease is eliminated using the PDI Alt Med process it does not come back again. TRH

  28. Gary says:

    Dr. H,
    I’m wanting to understand a little more about the products in the Peyronie’s disease large plan vs. the alternative large plan. The photo displaying items in the large plan appears to include an electrical appliance, and the more expensive alternative large plan does not picture this appliance. Presumably the alternative large plan has more internal remedies, but from the information available, it doesn’t seem reasonable to leave the decision to the patient. Remember, we know very little! If money were not an issue, what would be your recommendation?

  29. Dr.Herazy says:

    Greetings Gary,

    Thanks for a good comment and an interesting question about Peyronie’s disease treatment.

    There are many ways to use Alt Med to treat Peyronie’s disease, for sure. While the four assembled plans are good starting points for treatment, it has been shown repeatedly in every case that no matter how or where a man starts to treat his Peyronie’s disease, the final plan that prompts his body to reduce or remove the internal scar tissue will always be (much) different than where he started.

    First things first, since I believe your comment about decision-making is most important: Using the physical condition of the internal PD scar (size, shape, density and surface features) as a comparison, marker or guide it is possible to KNOW how to manage a treatment plan. With this information the dosages of the starting plan are gradually and slowly increased, and the plan is often times expanded with new and different kinds of treatment (CoEnzyme Q10, L-arginine, ultrasound, gentle manual stretching, etc.) that were not part of the original plan. All this is accomplished by the man with Peyronie’s disease using the information and ideas provided to him by PDI to develop his plan in the best way possible. No one is left hanging or confused about what to do. In this way, I have to take gentle disagreement with you that “it doesn’t seem reasonable to leave the decision” to the man with PD to help himself. Give yourself more credit. Alt Med treatment of Peyronie’s disease, as PDI has laid it out on this website, is not all that complex; if any difficulty or question arises during your self-treatment, you will be given all the help and information you need to keep going forward.

    When the Alternative Large Plan was introduced a few years back, it was added to accomplish a few different things. First, to put all the instructional or educational products (books and videos) in one plan. Second, to put Neprinol into one plan. It was also created to add a few different products into the lineup that are not found in plans, the gentle stretching video and Quercetin-Bromelain. And lastly, to feature the larger size supplement bottles in order to reduce cost. None of the plans can do it all or have it all for everyone; there is too much customization of any plan as it evolves over time to consider any of them as no more than starting points.

    To answer your decisive question, after having seen well over a thousand men plunge into Peyronie’s disease Alt Med treatment, if money were not an issue but only results mattered, I would suggest that a man starts with: 1. Standard large plan, 2. “Peyronie’s Disease Handbook,” 3. Gentle Manual Penis Stretching DVD. This would be a great start for most guys. This is not to suggest that this list is a magical combination of treatment, but only that it would be the best starting point for most men. Good luck to you, sir, in your Peyronie’s disease treatment. TRH

  30. Gary says:

    Thank you, Dr. H, for your considerate response. One part of my question I did not see answered concerns the image of the “appliance” on the Standard Large Plan. Could you please comment?

    Thanks again!

  31. Dr.Herazy says:

    Greetings again, Gary. As the caption below the image of the large plan contents indicates, this white/chrome apparatus is a major portion of the “3MHz Ultrasound Machine.” TRH

  32. Aaron Brizendine says:

    I am concerned about having Peyronie’s disease. I have recently noticed a bit of a bottleneck/hour glass effect kind of towards the base of the penis and have also been having trouble getting erections…however I don’t think that I really notice much curvature nor any pain whatsoever. Also when I do achieve an erection it looks exactly as it always has. Is it possible that I have Peyronie’s Disease or could it be something else?
    Thank you!

  33. Dr.Herazy says:

    Greetings Aaron,

    Based on the description you provided, only one finding suggests you might have Peyronie’s disease: Trouble getting an erection. However, erectile dysfunction or ED can be caused by many things.

    What does not sound like you have Peyronie’s disease: 1. Bottleneck or hour glass deformity apparently present when you are flaccid, not erect. 2. Normal appearing erection when it occurs. 3. Absence of pain. 4. You did not mention any small lumps or nodules (plaque) below the shaft surface, nor any genetic predisposition, nor loss of penis size, and you did not mention any trauma or drug use that could be associated with Peyronie’s disease.

    You need to go to your family doctor or a skilled urologist to determine if you have Peyronie’s disease. Based on the conflicting information you provided I would suggest you do not have PD, but that is only a guess. The missing finding that would tend to confirm or deny a diagnosis of Peyronie’s disease is the dreaded PD fibrous plaque.

    Good luck, and go for that examination soon so you do not worry needlessly. TRH

  34. Jerry Hayes says:

    Dr. Herazy,
    I was recently diagnosed with Peyronie’s disease. I am 4 weeks into this. My doctor wants to wait 6-12 months for it to stabilize. Then wants to do injections.I’m afraid to wait that long and don’t want injections.
    I have hour glass shape and 30 degree bend sharply at indentation area. i can maintain an erection and have no pain during erection. However, after ejaculation, erection is immediately gone and bend seems more pronounced. I am 58 years old. Your large treatment doesn’t seem to fit all my symptoms. I am in good shape and don’t take Viagra or anything like that. Intercourse is mildly difficult. Mainly due to the worry of injury. Would you suggest the medium treatment for my Peyronie’s disease?

  35. Dr.Herazy says:

    Greetings Jerry,

    You are very wise to want to avoid any injections into the penis. Many of the MDs who I work with who are treating their own Peyronie’s disease say they would never inject any drug for any reason into their penis lest they injure the delicate layer of penis tissue known as the tunica albuginea. Injury of the tunica albuginea during sex or sports is commonly known to cause Peyronie’s disease for reasons that are widely known, discussed a agreed upon in the medical literature. Yet, in spite of the widely acknowledged way that Peyronie’s disease results after direct injury to the tunica albuginea, most MDs think nothing of treating the penis like a pin cushion. At least I know from first hand experience that MDs who treat their own Peyronie’s disease take a far more conservative and reasonable approach for their own problems. For more information about this subject, go to a response I sent to an MD who asked about penis injections. Scroll down to the bottom of the page on

    You ask if the large or medium Peyronie’s disease treatment plan is more appropriate for you. I cannot answer that question because I am not your treating doctor. I can tell you that the larger plan tends to be more effective than the medium plan regardless of the details of the individual case because the larger plan is broader and more diverse to support and sustain natural healing. I suggest you use the largest plan you can afford during a 4-5 month treatment period when you aggressively and faithfully use whatever plan you choose to help your body correct your Peyronie’s disease. TRH

  36. kebede Birru says:

    I am a health worker/ Lecturer in St Paul’s Hospital Millennium Medical college in Ethiopia, I have Peyronie’s disease since one year, Can I use Pivotal product/ Trebinase 320,000 FUs per capsules to treat my problem? Is it helpful?

  37. Dr.Herazy says:

    Greetings Kebede,

    Sorry to learn of your Peyronie’s disease. I do not have any personal experience with Trebinase. My experience is working with those enzyme products found on the PDI website: Neprinol, Fibrozym,Nattokinse, Inflamazyme, Bromelain 5000, etc. I know these products work because PDI receives 8-10 reports of moderate to marked reduction of Peyronie’s disease scar formation for every one report of failure. However, more than systemic enzymes are used to eliminate the Peyronie’s disease fibrous tissue. PD is a difficult problem to treat and requires a broad assortment of various nutrients to enable the body to heal this problem. For additional information about treatment please review this website. TRH

  38. Howard S. Paul, M.D. says:

    Hello again Dr. Herazy, I purchased the Neprinol from this site to treat my Peyronie’s disease. It has arrived. I still can not find any information on the amount of CoQ10 in it. Can you advise? Thank you in advance,


  39. Dr.Herazy says:

    Greetings again Dr. Paul,

    As I responded in an earlier post to you, “Most vitamin companies attempt to keep as much information about their formulations private, so as to retain a competitive business advantage. This way no other company can accurately copy their products. This is different than in drug reporting in which information about ingredients is complete. Even the exact contents of enzymes, which are the primary ingredient of a product like Neprinol, are not listed.” The exact CoQ10 dosage in a capsule is not provided. This makes it difficult to track overall dosages of individual nutrients, but does protect the manufacturer. Not a good thing, I understand. Sorry. TRH

  40. Bob says:

    I am 75 and in excellent health. My urologist prescribed Finasteride to treat my BPH around 3 years ago. I started to notice a slight curvature after about a year. The doctor indicated that Finasteride does not cause Peyronie’s Disease and left me on it. After 2 years, I had a very pronounced ~90 degree curvature to the left during erection. I have not noticed any scar material and there is no pain. However, it is bottleneck shaped during erection like Peyronie’s disease. It is not noticeable when not in erection. The doctor did allow me to discontinue the Finasteride after the two years but he never would say that Finasteride may have caused the Peyronie’s Disease. It has now been almost another year, without BPH medication and there is no change in the curvature. I have been on statins (now Pravostatin) for high cholesterol for around 16 years. For me, the Peyronie’s Disease is a cosmetic issue.

  41. Dr.Herazy says:

    Greetings Bob,

    Peyronie’s disease can result from certain medications. Some of these drugs are widely known to cause Peyronie’s disease, such as the statin group. Other drugs only suspected to cause PD such as Finasteride (Propecia) in spite of considerable evidence. A book written by Dr. John Briffa discusses “statin side-effects that the pharmaceutical industry appears not to want you to know about.” In it he discusses the untold story of how the drug industry passively avoids and actively prevents information from coming out that would result in certain drugs being taken off the market.

    Your doctor is technically correct from the narrow standpoint about Finasteride causing Peyronie’s disease. Medical doctors are told what to think. They are given certain certain basic information (“standards if practice”) about what is the “right way” to practice medicine: how to treat, what to prescribe, how to perform surgery, how to conduct themselves in practice. So long as they strictly follow those standards and norms of medical practice they will typically be considered to be practice good medicine and they will be supported and even protected by their fellow medical doctors. If they do as the standards of practice dictate life will be good to them.

    The drug industry dictates and controls much of the standards of medical practice, and herein lies the rub. Once a drug is on the market it is difficult to remove. Your doctor knows that currently Finasteride and the statin drugs are strongly suspected to cause Peyronie’s disease. Because the standards of practice say there is “no proof” of it he is safe in prescribing and defending their use. He is technically correct. Even though there are countless stories of Finasteride resulting in Peyronie’s disease, with countless lawsuits and reports in the medical journals related to Finasteride resulting in Peyronie’s disease, the current standards of medical practice contend it is not so. It is the drug industry that keeps their huge financial ship afloat with many of these dangerous and questionable drugs. Eventually what will happen is that the wave of public opinion and new evidence will force the drug industry to admit what has been long suspected and secretly known. In the meanwhile men like you will develop Peyronie’s disease — and many other terrible side effects from these drugs.

    Peyronie’s disease is sometimes corrected by the body’s ability to heal. What we do on this website with Alt Med results in some rather nice changes in PD in a fair percent of cases when men follow the instructions we provide. Since 2002 I have seen that 8-10 men report moderate to marked improvement of their Peyronie’s disease when using the PDI concepts for every one report of failure. Please review the information on this site, You might be able to do something for your Peyronie’s disease, TRH

  42. Ricardo says:

    Hello. I’m 44 years old, I have the peyronie’s disease around 14 months ago, I have sugar problems (200-250mg/dL) so I’m not healthy. What kind of treatment do you recommend for me to get?


  43. Dr.Herazy says:

    Greetings Ricardo,

    Peyronie’s disease treatment is always made more complicated by elevated and uncontrolled blood sugar. Diabetes alters blood chemistry in many ways, hence it affects many areas of the body including the soft tissue. This is the reason skin problems are common complaint (rashes, skin eruptions that do not heal, frequent infections) for diabetics.

    I recommend that you aggressively use the largest Peyronie’s disease treatment plan you can afford for at least 2-3 months to see if during this time you can see reduction of the size, shape, density or surface features of your PD scar tissue. You must closely follow the information you will be given.

    Many men with Peyronie’s disease have elevated blood sugar levels, and still can respond to therapy if they are faithful and careful about treatment. Of all the men who come to PDI for help, 8-10 report moderate to marked improvement of their Peyronie’s disease for every one man who is not successful. It is not fast or easy treatment, and it does not always work, but it is certainly worth the try; it is certainly better to something than to do nothing. TRH

  44. eric says:

    I’m 62 and in excellent health. I have never had ED and have never taken any ED medication. About 10 years ago, I noticed that I had a slight curvature, but experienced no pain. About 6 months ago, while having intercourse with my partner on top, i slipped out and she came down on me. There was no snap but i lost my erection. Since that time, i have painful erections and I have noticed some plaque, that I never noticed before. The strange thing is that, I no longer have any curvature, but think i have lost some size. It seems that i had curvature from injury on bottom side of penis and now injured top side, which offset the curvature. By the way, my erections are only painful when wearing pants or underwear, once i remove my pants the pain is gone, but then i feel it again during intercourse.

    3 questions:
    1) have you ever heard of a 2nd injury (on opposite side of 1st injury) causing curvature to straighten?
    2) is the any reason that I need to avoid intercourse, considering that I’m now very careful to avoid another injury?
    3) which Peyronie’s disease treatment plan do you recommend?

  45. Dr.Herazy says:

    Greetings Eric,

    Thanks for the interesting questions.

    The particular sexual intercourse position you describe (female superior missionary) is the classic mechanism of injury that often leads to Peyronie’s disease. For a man who has PD, or wants to avoid PD, there is a simple maneuver to use to make the female superior position safer. Simply wrap one or two arms loosely and gently around her waist to limit her upward movement to keep it within a safe range when you feel you might become unconnected. She can have the fun of the ride as she pleases, while you protect yourself.

    Yes, I have heard of 2nd injuries altering existing Peyronie’s disease curves. A PD curved penis exists only because of the way that the internal scar or plaque influences the internal architecture and angles of tissues within the shaft. Very severe Peyronie’s disease, with significant internal scar tissue, can result in little curvature if the scars are evenly spaced and the internal disruption is symmetrical. Minor Peyronie’s disease, with little internal scar tissue, can result in terrible curvature if the scars are only located in one area of the shaft and pull unevenly only from one small focal point. It is possible that in your case the 2nd injury merely evened out or balanced your internal scar arrangement.

    No need to avoid sexual intercourse. Be more mindful about possible re-injury. Use caution when using sexual intercourse positions in which your partner can potentially uncouple with you. In Peyronie’s disease, sex is not the problem; wild and crazy sex is the problem.

    I recommend that a man follows the most broad and diverse treatment plan he can afford to use for at least 3-4 months to see if his tissue can respond. This is a good place to learn about the PDI treatment plans. We receive spontaneous reports from 8-10 men telling us about moderate to marked improvement of their Peyronie’s disease when correctly following our treatment protocol, for every one report of failure. Those are good odds for improvement, but you have to treat your PD correctly. Peyronie’s disease is a stubborn and difficult problem to deal with. Good luck to you, sir. TRH

  46. RC Postel says:

    I’ve had the wild ride uncoupling with wife on top and with too much forceful downward thrusts cause that disconnect and believe that incident caused peyronie’s disease to develop over time, it’s been a few years but caused the bend towards the right, not pain and intercourse can still take place if redirected straight. I exercise eat mostly organic and yet am 60+. not sure which plan would be most advantageous.

  47. Dr.Herazy says:

    Greetings RC,

    Most penis injuries that lead to Peyronie’s disease happen just the way you describe: Man on his back, woman on top, exaggerated thrusts that cause uncoupling, woman comes down hard on erect penis, causing forceful and sudden bending of penis. It is a sad, painful and common story, with a usually sadder ending.

    The most advantageous plan I recommend is the largest a man can afford to continue for at least 3-4 months to see how well he responds. During this time he must faithfully and aggressively follow the PDI protocol as instructed. When he does, 8-10 men report moderate to marked improvement (reduction) of the PD scar tissue in terms of size, shape, density and surface features, for every one man who reports no response. This reduction of the internal PD scar results in improvement of the curved penis, reduction of pain, improved erection quality and/or return of lost size. Every man is different, so often the plan must be modified in some way for best results – again all this is explained in the PDI protocol that is provided with each order.

    Please let me know if you need any questions answered. TRH

  48. KG says:

    Doc. I am relatively young (under 40) and was diagnosed with Peyronie’s disease recently. I suppose I’ve been seeing symptoms for about 3 months. I got the large plan out of an overabundance of caution. My question is that I am wondering why Ubiquinol (CoQ10) and Acetyl-L-Carnitine are not a part of any plan. I understand these are staples of any supplement-based Peyronie’s treatment plan.

  49. Dr. Herazy says:

    Greetings KG,

    Great question about Peyronie’s disease treatment. Thank you for asking.

    The large plan is not the “Everything Plan.” The large plan consists of 11 diverse therapies that support healing from a wide variety of directions. Using it aggressively has shown itself sufficient to bring a lot of men around to make improvement of their Peyronie’s disease in most cases, when it is used as suggested. Partial and occasional efforts get poor results. However, some men need more help, or a different kind of help.

    When the large plan does not trigger the kind of healing response that is expected, we begin to make modifications in the basic plan, searching for ways to help the body respond better. Part of that search is to sometimes add additional therapies into a plan, like CoQ10, acetyl-l-carnitine, or perhaps a different enzyme profile. We search and modify existing plans until we get a change in the size, shape, density or surface features of the PD scar tissue. It might take a small tweak to get the job done, or a large teak, depending on circumstances of each man.

    When these plans were put together it was decided to not make them larger or more complex than they needed to be. After all, these plans can be seen as starting points in treatment; a place to begin to see how the PD scar responds to an increase of nutrients and therapies directed at it. If the original plan by itself gets the job done, great. If not, we modify and sometimes increase it with therapies we hold in reserve — that are usually not needed. But when they are needed, we have them in our arsenal.

    Thanks for giving me this opportunity to lay these ideas out for the readership. TRH

  50. Dr. Herazy says:

    Greetings Mike,

    No, you can still start treatment with PDI natural remedies. It seems that the ability to respond and remove the fibrous tissue is not limited to a certain time range. When you supply what the body needs, it does what it can to eliminate the plaque to the best of its ability. We have worked with men who had Peyronie’s disease for 12 years and more, and they made improvement. You will only know what your body can do, until you give it a good solid try. TRH

  51. Bob says:

    Would you recommend using a traction device such as RestoreX with your Peyronie’s disease treatment therapies to increase the rate of success?

  52. Theodore Herazy says:

    Greetings Bob,

    Thanks of the question.

    Over the years, I have written perhaps a dozen articles about the use of penis stretchers — regardless of the name of the current hot product that is trying to break into the market — as they relate to treatment of Peyronie’s disease. Penis stretching to help PD is an interesting idea, but it does not work. Peyronie’s disease is not like having a bent paper clip below your belt; the problem only has to be stretched and straightened to be corrected.

    As you have likely learned by now, Peyronie’s disease is a very complex condition. It cannot be stretched away. Here is why: Normal, flexible soft tissue of the penis will absorb all the stretch that is applied by the mechanical stretcher to the penis before the abnormal fibrous scar tissue will have an opportunity to be stretched. It is like the saying, “A chain will break at its weakest link.” In this case, the normal penis tissue will give way and stretch because it is weaker in comparison to the fibrous PD tissue that does not stretch. Any stretching of the penis is due to normal tissue lengthening, not PD tissue lengthening. That is why these stretching websites come and go.

    All the big name and expensive penis stretcher products from just a few years ago are gone. Many of them run into financial troubles because of lawsuits related to injury caused by overstretching, and aggravation of Peyronie’s disease. What happens is that the healthy tissue is overstretched, and often develops more PD, and not much happens to the original PD tissue.

    If you want to read a longer and more detailed explanation, go to Peyronie’s Disease and the Penis Stretcher.

    PDI gets reports of moderate to marked improvement of Peyronie’s disease from 8-10 men, for every one report of failure, when our treatment protocol is carefully followed. No one reports injury or aggravation of PD from our methods. TRH

  53. Theodore Herazy says:

    Greetings ZM,

    There are several articles on the PDI site about Extracorporeal Shock Wave Therapy used to treat Peyronie’s disease. Please use the Search function for that topic for a more detailed answer. However, a short reply is that I have not received any reports about ESWT from men telling me that it helped reduce or eliminate Peyronie’s disease. The only kind of commentary I hear is that it is expensive, and that it can be a painful procedure and it can significantly bruise the penis. You see, ESWT was originally intended and designed to break up kidney stones. The strength and frequency of the sound waves are created to break up hard stones within the body. Every several years interest in ESWT seems to surface for a while, and then it fades away. This appears to be the case again.

    Aloe vera gel has been tried many times and in many ways as a Peyronie’s disease treatment and has never proven itself. PDI did an aloe vera research project in 2008 with a few dozen men. We found no evidence of improvement of the size, shape, density or surface features of the PD scar tissue after using aloe vera gel.

    The most improvement we have seen using natural treatment is with the current PDI treatment protocol, especially the large plan. We get reports of moderate to marked improvement of Peyronie’s disease from 8-10 men who use the large plan exactly as suggested, for every one report of failure. Those are some very good results. It requires time and work to get good treatment results, but it is possible when the work is done properly. There is no fast or simple way to do it. Review the information on this site and learn how we have been helping men since 2002. TRH

  54. Daniel Maksa says:

    Greetings to everyone,

    I have been dealing with Peyronie’s disease and an hourglass deformity at the base of the penile shaft and goes all around, more visible on the right side. It does not cause a curvature, hence I can’t get approval for xiaflex treatment. However, it causes severe erectile disfunction as the veins leak out and fail to keep the blood inside the penis. Ultrasound cannot detect any calcification in the affected area nor in any other part of the penile shaft. It’s been going on since 2017 and not getting any better or worse. Do you think your treatment plan could still work for me?

  55. Theodore Herazy says:

    Greetings Daniel,

    Five years is a long time to live with Peyronie’s disease and an hourglass deformity. But, that does not mean you cannot do things to help yourself. The body has a great, even miraculous at times, ability to heal and repair if given some help. We work with men with Peyronie’s disease that has continued a lot longer than yours — ten years and more — and they can still respond.

    PDI gets great results, considering that MDa think surgery is the only treatment option for Peyronie’s disease. That is too bad because surgery for PD is famous for complications and terrible recurrences even a short time after surgery. For over 20 years PDI has helped 8-10 men reduce their PD moderately to greatly using the large plan, for every one report of failure. Those are great odds for improving your PD problem. But you have to work at it.

    There is no way to know if, or how much, your tissue can respond until you give it a good try. Improved circulation due to reduction and softening of the internal Peyronie’s disease scar tissue is usually one of the earlier and most welcome changes that happen on a large PDI plan. We work with our customers to get the best response possible; no one is ignored.

    Let me know if you have any questions or what to discuss your problem. TRH

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