Cortisone injections and Peyronie's disease

My doctor wants to put cortisone injections into my Peyronies scar, what do you think of that?

Will steroid injections reduce the inflammation and pain of my Peyronies?

My opinion is that it is risky to use cortisone injections as a Peyronie's treatment.  While a temporary and variable reduction of pain does occur in some cases, but not all, it is not worth the limited benefit that makes future Peyronies surgery more complicated and dangerous should it become necessary.  There is good reason to think twice about using steroid injections for this purpose.  This website has presented an earlier article about a closely related topic, Peyronie's disease treatment via direct drug injection.
It would be good to talk to your doctor about other treatment options or to consider using Alternative Medicine as a way to increase your natural ability to eliminate the Peyronies scar.  The PDI website explains how this can be done without the use of drugs and surgery.
In the 1960’s steroid (cortisone) injections were used as a Peyronie’s treatment under the theory that they would reduce plaque or scar formation because of the inhibitory effect cortisone has on fibroblast cell formation. Since fibroblasts are cells that make fibrin, and fibrin makes collagen in the body, with fewer fibrin cells the ideas was that this would result in less collagen produced during scar formation.
This treatment for Peyronie’s was used rather extensively until the mid-1980s when it became obvious that it did not consistently or greatly reduce collagen at the Peyronie’s plaque. And of equal concern was the observation that these steroid injections were causing penis tissue weakness (atrophy) of blood vessels, nerves, and all connective tissue of the corpora cavernosa and tunica albuginea of the at the site of the injections near the Peyronie’s plaque. These steroid injections resulted in weak and fragile tissue that would easily tear when a surgeon would try to sew it together during surgery, or worse yet would tear after surgery or heal slowly or not at all.

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It took a long time to notice and correlate this problem because virtually all of the studies of using cortisone injections in Peyronie’s disease did not use a placebo control, and they performed with only a small number of patients who reported their improvement subjectively without objective measurement of progress in terms of pain, plaque formation and deformity reduction.
Seldom did the steroid injections actually have a beneficial effect on the eventual Peyronie’s disease outcome, but had an undesirable side effect that made Peyronie’s surgery complicated and less effective. The problem was that the broad tissue destruction caused by the cortisone made the tissue so weak and compromised that a surgeon could not later go into that same area to suture the tissue closed at the site of a surgical incision, or expect the sutures to hold on the weakened tissue. If penis surgery was done it often resulted in frequent bleeding and repeated opening of surgical wounds. Once it was seen that cortisone injections made it difficult to do good surgery later, the practice began to fall out of general use.
In addition, the practice of using cortisone injections for treatment of Peyronie’s disease did not take into account the harmful effect of placing a series of multiple needle punctures into the scar material and the tunica albuginea tissue of the penis. Later clinical observations have shown that these frequent and repeated needle punctures act as additional trauma to tissue that has already shown itself capable of producing excess scar formation to repeated small injury. This has also proven to be the case when a series of multiple injections of other drugs like verapamil and interferon are used as Peyronie’s treatment. The clinical results of these other drug injections have not provided positive or encouraging clinical results that were any better than those of cortisone injections.

Where can I purchase the 3MHz ultrasound machine to treat my peyronies?

Where can I purchase the 3mhz ultrasound machine to treat my peyronies?   I couldn't find it here.  rabalar.

Greetings Rahalar,

Please go to 3MHz ultrasound treatment of Peyronie's disease for the information you need.  TRH

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How can I fix my curved penis when I get erect?

Good day,

I have curve to the left and is causing me serious trouble when I got erected.

How do I fix my curved penis?



Greetings Pongo,

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You can spend a little time and effort reading and learning about Alternative Medicine treatment of Peyronie's disease. I suggest you go to “Start Peyronies Treatment” found at the top of the PDI home page and get busy. You can also read any of the hundreds of answers I have already given to this same question that appears in this Question/Answer section. TRH


Easy treatment for Peyronie's disease?

hi doc plz tell me the correct and easy way to make it straight i m soo worried doc plz help me!!! guide me with natural and easy exercise in treatment thank you…


Sorry to disappoint you but there is no easy or fast treatment for Peyronie's disease. PD is not that kind of problem.

You seem to be a young fellow who might be inclined to believe the nonsense of some of the bogus websites that promise fast and easy Peyronies cures when nothing like that exists. Mystery herbs from Pakistan or mechanical penis stretchers will not correct the curved penis that is worrying you. Everyone believes that penis stretching will work until they learn it is a painful process that many men cannot do for more than a few minutes and is not effective because having Peyronies is not like having a bent paperclip.

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You will have to do some work, maybe even a lot of work, to help and support your body's ability to recover and reabsorb the Peyronie's plaque. It can be done and it is being done daily, but always with effort and time. All you have to do is go to Start Peyronie's Treatment and start learning and reading.

If none of this sounds appealing to you, you can always come back to the Peyronie's Disease Institute website when the easy methods have failed and you might be a bit worse.

Let me know if i can help you in any way. TRH


Now that my Peyronie's disease is gone should I continue taking the supplements?

I have had Peyronie's for approximately two years. I had about a 45 degree bend upwards and about a a 15-20 degree bend to the right. I noticed that I had a large scar along the top of the shaft about 2″ and a small nodule about 1/4 inch in diameter on the right side. I obtained your gentle manual penis stretching video and started with the exercises and took PABA, Vitamin E, Nattokinase as you suggested in the instructions PDI provides. I continued with this stretching exercise and the vitamins and enzymes and have now straightened out the shaft. I do not feel any more scar tissue. I was wondering if I am going to have to continue on with the PABA? I will continue to take the other natural vitamins and supplements as I was taking before i developed the Peyronie's, but I did not ever before take PABA so i wonder if I should continue with that. Thanks for your help.


First of all, congratulations on your successful treatment of Peyronie's disease. Many people doubt that they can do what you did. I get this kind of report from people around the world several times a week telling me that they have recovered from their terrible Peyronie's problem by following the simple directions and ideas found on the PDI website. Good for you.

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I doubt you will have to continue with the PABA or continue doing the gentle manual penis stretching technique now that your Peyronie's plaque is gone. Since 2002 I have been consulting with men about Peyronie's disease and in that time we have had some really great results. In all these years I have never had anyone come back to me a year or two or five years later to report that their PD has come back when they stopped taking the PDI Peyronies treatment plan they used to recover from their problem.

However, I would say that half of the men who get over their Peyronie's disease say they will continue with certain parts of it because they believe they get general health benefits from certain products (Neprinol, nattokinase, vitamin E, acetyl-L-carnitine, etc.) I have recovered from my own Peyronie's disease now for about ten years and still take Neprinol, Omega T, and vitamin E because I am convinced of their broad health benefits.

Again congratulations on your great Peyronie's treatment story. TRH


Is it true nothing can be done for penis shrinkage caused by Peyronie’s disease?

I hurt my penis during sex. At first it had a curve but that went away and instead the penis has shortened drastically.  Sex is no longer achievable and a simple act like urinating into a toilet bowl is a problem because the penis has shrunk so much that I cannot point it at the bowl.  I either have to drop my pants or sit on the toilet and push the penis down to prevent it from urinating at 90 degrees.

I live in South Africa and the urologist has said there is nothing that can be done.  Is this true?




Greetings Wally,

The statistics found in medical journals and the internet about penis shrinkage related to Peyronie's disease are variable and of questionable accuracy due to the natural of the problem.  As I remember, the published rate of reduction of Peyronies men who experience penile length and/or girth is said to be 25-50%.  However, based on my conversations and email from men with PD I would put that number easily in excess of 75%.   What you report is not at all uncommon.  It is  a consequence of the excess fibrous tissue build up that causes contraction of the deep soft tissue of the penile shaft, and also can cause distortion, such as a curved penis or an hourglass, bottle neck or dent deformity.

When your urologist told you noting can be done for this problem, he/she should have more accurately said there is nothing that medical practice can do to help you.   There is a lot you can do to help yourself.  If about half of the men who develop Peyronie's disease experience a spontaneous remission or self-cure of this problem, then it is obvious that these men are capable of curing their own problem.   PD is cured half of the time without any outside help by the natural healing process of the body.   The PDI concept for treatment of Peyronie's disease is simply to assist or support that same natural healing process by using a combination of vitamins, minerals, herbs and enzymes and other techniques that allow the body to heal better – to increase the odds that you too can care your PD like you should have in the first place.   Your urologist only says there is nothing that can be done to help you, only because he/she does not have a drug to use for that purpose.  "We do it my way, or no way."  What arrogance. 

Probably the best place for you to start looking for information about Peyronie's treatment using Alternative Medicine is from this link from the Peyronie's Disease Institute, "Start Peyronie's treatment."  

Believe me, you would be shocked to learn the number of MDs who contact me from around the world about using Alternative Medicine and the PDI approach to Peyronies treatment when one of them develops PD.    Drugs and surgery are for patients, and when one of them has a bent penis they they suddenly want to be very conservative with what they do.  TRH

What assurance is there this Peyronies disease treatment works?

What ass

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urance is there after spending hundreds of dollars on your treatment options that the Peyronies disease will be helped?


Oh, I see. You are looking for me to give you a guarantee that the Alternative Medicine plans will work before you start.

No worthwhile and accepted medical treatment or procedure provides a guarantee of results. Aspirin does not guarantee anything, no blood pressure or cholesterol medication manufacturer can guarantees results, no guarantee comes with Viagra, and certainly no surgeon guarantees even the most minor surgery. Your dentist does not guarantee the Novocain will numb your gum, and that is why he keeps asking you while he is drilling your tooth if you can feel anything (he/she does not know if it is working the way it should). Yet you ask me to guarantee treatment of Peyronie's disease.

Within the world of Peyronie’s disease treatment I seem to notice most often a guarantee attached to ads and promotions for single remedy products that are sold by overseas companies. To keep myself informed about these products and to determine if there might be anything to their claims, I have on several occasions attempted to contact these companies that “guarantee” results. Never have I had any success in having a single one of these companies return a phone call or answer an email inquiring about their products. This, in my opinion, speaks volumes about the worth and credibility of any guarantee from companies that offer such a promise. I think the informed buyer had certainly beware meaningless and silly guarantees for results with a condition so difficult to treat as Peyronie’s disease.

All information found on the PDI website points to the direction that each man must understand that Peyronie’s disease is an extremely tough problem to deal with, hence the lack of interest or effective treatment from the medical community. The condition is marked by many variables and almost no constants that are commonly found in other health problems that make treatment possible. PD is so variable it lacks those benchmarks, due to the variables you correctly anticipate must be part of this response. It is the variables of PD that make PD what it is, and complicate all forms of treatment of it. How long a person chooses to treat his PD is a personal choice, as are other aspects of undergoing Alternative Medicine treatment. I would speculate that on average, a man – if he is going to see results at all – will tend to notice change within the first 3-4 months of care using the PDI concepts of Alternative medicine treatment. Sometimes noticeable change occurs in a few weeks, and other times not at all.

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Further, there is no way to predict or guarantee outcome of treatment because there is no way for me to assure that a man will actually go about treating his PD as he should.

That is just the truth of it. I am sure if you would ask your family medical doctor that same question you would get the same answer.

Perhaps you are simply not aware that 50% of the cases of Peyronies disease will clear up on their own, demonstrating that the condition is indeed responsive to self-repair or self-healing. The PDI concept of treatment for Peyronie’s disease is simply to do as many things as possible – all at the same time – to help and support and encourage the body in its effort to cure its Peyronie’s problem. We are not trying to get your body to do something special like growing an extra finger or raising your IQ 100 points. We are only attempting to assist the body to heal the Peyronie’s plaque like 50% of men will do naturally. It is as simple – and complicated – as that.

I suggest you go to the PDI website to read more about this process of natural healing, at “Peyronie’s Treatment Philosophy.” You simply lack confidence in yourself and this concept because you do not understand it. TRH

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Any advice about my Peyronie’s disease?

Dar Dr. Herazy,

I am a 46 year old man and 6 years ago I noticed a curve in my penis when erect and a loss of significant size- width and length.   I do not have pain though and went to a urologist (hard to do, embarrassing) and the guy was not cool.  He grabbed my flaccid penis for a second and told me to take l-lysine or something.   I am really at wit's end and have basically given up a life of intimacy because of this.  I don't want a weird operation, but feel my case is not super severe.  It certainly hasn't worsened over the years.  Any advice?



I am not sure about your reference to l-lysine, an essential amino acid, being prescribed by your doctor as a Peyronies treatment.   I suppose it is possible, but the connection between the two is not direct. Further, although you did not come out directly and say so, I will assume that your urologist gave you a diagnosis of Peyronie's disease.

There are three forms of carnitine: L-carnitine, acetyl-L-carnitine and proprionyl-L-carnitine.  Acetyl-L-carnitine (ALC) is the principal form used in most research and treatment of Peyronie’s disease (PD).   The two primary building blocks of carnitine are the essential amino acids lysine and methionine.   While this might be the basis for the thinking behind prescribing l-lysine to you, it seems more direct to simply prescribe that you take acetyl-L-carnitine.  Perhaps you were overwhelmed, as most men are when they first learn that they have Peyronies disease, and you misunderstood.

Peyronie's surgery is the most common medical option that is presented to a patient, even suggesting surgery before more conservative options are tried.  PDI is not against surgery as a treatment of Peyronie's disease, but it is best considered as a last resort, not as a first measure as some doctors are inclined to do. Please be very careful about considering any Peyronie''s operation since the negative consequences can be devastating. 

The fact that the curvature of your penis has not worsened over the years does not mean it cannot do so at any time.  It is always wise to be cautious and aggressive in treating yourself to eliminate the Peyronie's plaque even if the distortion is slight and stable, because any case of untreated PD can worsen suddenly. 

My advice is to spend some time on the PDI website learning about the Alternative Medicine treatment of Peyronie's disease, and how you can do simple things to increase your body's ability to heal the Peyronie's plaque like the 50% of men whose PD just goes away naturally.  Our approach is not radical; we area only attempting to increase  or support a natural healing process that happens in half of the cases of PD.   It is not like we attempt to get you to grow a 6th finger on your hand or to jump over the moon.  This is all basic stuff about natural repair and attempting to promote normal body function.   A good place to begin looking is "Start Peyronies treatment."    TRH

What Peyronie's treatment options or products are currently available from PDI?


I'm 35 and about 2 months ago, I noticed a slight deviation on my erect penis (right side) and when I mentioned it to my urologist he said I may be developing Peyronie's Disease. I am concerned it will get worse. I'm wondering what treatment option(s)/products you currently have available on your website you think I should consider to correct this.


Greetings Joe,

There are well over 500 pages of information about using Alternative Medicine for treatment of Peyronie's disease on this website. It seems like you have not looked around the site very much or you could not have asked this question.

I suggest you go to Peyronie's treatment products page to see the list of things you can use to improve your ability to heal and eliminate the Peyronie's plaque. With just a little effort on your part you can get an idea about putting a plan together for yourself if the large, medium and small plans do not suit you. You can get lost in this site for a few days reviewing all the information that is readily available to you. Just click on a few links and see what you can learn. TRH


Best Peyronie’s disease treatment, Neprinol 300 or Neprinol AFD?

Neprinol reduces inflammation and tissue damage

Neprinol is a completely vegetarian blend of several different enzymes that have tested to have over six time’s stronger activity to break down fibrin than the leading animal based enzyme blend product.  The enzymes in Neprinol have been shown to be clinically effective in supporting C-reactive protein (CRP) levels when taken as directed.  In this way Neprinol promotes normal levels of anti-inflammatory markers in the blood stream that are part of the physiologic response of the body while  dealing with acute (sprain, strain, overwork) and chronic (arthritis, most soft tissue disease, stroke, blood vessel disease) injury.  As a result Neprinol enzymes will assist the body in its effort to eliminate from the blood stream damaged red and white blood cells, fibrin, any protein material that is part of the inflammation process, as well as other cellular debris and foreign protein that can accumulate in the blood.

Neprinol AFD important in treatment of Peyronie’s disease because it affects fibrin

Fibrin deposition in Peyronie’s disease plaque

Immediately after injury occurs in the body, a protein called fibrin is deposited at the site of injury to act as a meshwork to trap and collect important blood cells and helpful components that create a clot that stops bleeding and promotes healing and repair of the recent injury.  This is normal.  After a period of time this mass of fibrin with it cellular collection changes so that the fibrin is removed and another protein called collagen fills in the spaces and changes the area of repair so that it resembles a fresh scar.  This is normal.  However, in Peyronie’s disease two abnormal things occur, for reasons that are not understood:  the fibrin does not leave the clot, and an excessive amount of collagen forms in the young scar so that it takes on a different name, a Peyronie’s plaque.  The way this fibrin and collagen collect and remain at the site of injury is consistent with repetitive injury to the small blood vessels of the penis.

The benefit of Neprinol AFD to Peyronies treatment is that it can break down and assist the removal of the fibrin that remains in the Peyronie’s plaque or scar.

Neprinol 300 most popular systemic enzyme sold by PDI

The ability to break down fibrin with enzymes, and to do it as economically as possible because it is a larger size bottle, is the reason some people call it Neprinol 300.  The high potency of two key enzyme ingredients, nattokinase and serrapeptase, address the concern about aggressively placing a systemic enzyme product as the foundation of treatment. Start by taking only four Neprinol 300 capsules daily, then slowly increase dosage while monitoring the size, shape, density and surface features of each Peyronie’s scar.  This is a great way to use this Alternative Medicine therapy for treatment of Peyronie’s disease. Neprinol 300 is recommended for both clinical use and therapeutic applications.

No difference between Neprinol 300 and Neprinol AFD

Whether you choose to call it Neprinol 300 or Neprinol AFD, these two terms are simply different names for the same potent enzyme therapy supplement that most people simply call Neprinol.

Neprinol continues to be by far the commonly used Peyronie’s disease therapy product.  Many times I have seen men who are following a particular plan that does not include Neprinol, and they experience slow or totally stalled results.  After adding Neprinol to that same plan it is common to learn that their recovery greatly improved from that point forward.

The name Neprinol 300 refers to the fact that Neprinol is bottled in either a 300 or 90 count bottle, for your benefit.  With the larger Neprinol 300 size bottle it is possible to take advantage of the reduced price of a greater supply and to purchase it fewer times; this is especially helpful for those who use Neprinol for chronic health problems that require prolonged treatment.  With the smaller Neprinol 90 count bottle it is possible to keep a smaller amount on hand for relief from occasional and mild overwork injuries or to simply get acquainted with the Neprinol product by taking a small amount of it.  By far, Neprinol 300 is a much more popular product.

The name Neprinol AFD refers to the primary purpose of Neprinol, as an Advanced Fibrin Defense therapy product.  Neprinol AFD is a name that tells the story that reduction and elimination of fibrin from the blood stream and tissue is what this product is all about.

Neprinol is safe

In over 10 years of use through the Peyronie’s Disease Institute there has been no report of any serious complication or adverse side effect associated with taking any systemic enzyme product like Neprinol, when it is taken in the way that we suggest.  Worldwide experience during this time has revealed, as well as clinical studies have demonstrated, that taking extremely large doses of this product does not result in a toxicity reaction.  Anyone taking a prescription for blood-thinning medication should consult with his treating physician prior to taking Neprinol.

Neprinol for Peyronie’s treatment

As good as Neprinol is when used to reduce Peyronie’s plaque material, it is almost always necessary to use several other in addition to the Neprinol to support and sustain the desired tissue changes.  Neprinol is best taken as part of an already good therapy plan, often used as a substitute for low dose nattokinase and serrapeptase supplements, although some men use all three products with very good results.

Neprinol AFD contains primarily serrapeptase, nattokinase, bromelain, and co-enzyme Q, plus a few other lesser ingredients. Other products also contain serrapeptase and nattokinase, individually, but few put these two in combination and none in the concentration of Neprinol AFD.  It is a more potent form of nattokinase and serrapeptase than if you would buy each in individual bottles, and the Neprinol 300 bottle itself is three times larger than most others that contain 100, to say nothing of smaller bottles with 60 or even 30 capsules.

However, in regard the idea of successful PD treatment is to not focus on any one particular therapy, even if it is a great one like Neprinol because the goal is to attempt to create a synergistic effect with several therapies taken at once for maximum therapeutic effect.  For this reason the Peyronie’s Disease Institute has always maintained that even if someone believes Neprinol (or any other) is a key PD treatment it should not be taken alone but combined for greatest therapeutic benefit.

No one knows how any one will respond to any or all of the 13 Alternative Medicine therapies found on the PDI website.  Some men report some positive results with just one therapy, but more men report better results when they take multiple therapies.  That is what the whole therapy concept of synergy is all about:  the more you do, the larger your plan, the greater the likelihood of promoting a favorable metabolic change to support and encourage scar reduction.  The PDI idea is not to “treat the scar” as a medical doctor would do, but to “treat the man who has the scar” so that his body can heal what is wrong with it.  This is a major concept shift for most medically indoctrinated people.  For this reason, as good a single therapy as Neprinol is, it is not recommended that anyone who is interested in earning good results in treatment of his PD scar should use just Neprinol – or just any one product – but several to create synergy.

Peyronies disease is a tough and terrible thing to happen to a man.  It takes dedication and persistence to overcome it.  Call it Neprinol 300 or Neprinol AFD, but definitely use it in a well diversified plan to break down the fibrin network of your Peyronie’s plaque material.  Success over this problem is never an easy victory, but always worthwhile.


Is this Peyronies disease?

I have 0 pain, 0 curve in erection and no hourglass look in erection.

However I am 18, and have had ed for 4 years. For as long as I can remember, on the occasion, My flaccid penis has a bit of the hourglass look. Also when it is night time, and I am extremely relaxed, and my flaccid becomes bigger, and almost a semi erect, it occasionally curves to the right which i just started noticing about 6 months ago. Also, after I urinate, occasionally I see my penis begin to curve right.

Again no pain, no bumps, no hourglass or curve in erection

I only see hourglass/curve in flaccid/semi erect.  Is this Peyronies disease?  If so will it get worse?  Can I send pictures to you?



Pictures would be of little help to reach a conclusion.

No one can say with any level of certainty based on the information you have provided whether your condition is Peyronie's disease or not.  These things are not diagnosed so casually or easily.   To know for sure what is happening, you must see a urologist and be examined for a formal diagnosis.

Having said that, it is my absolute guess that you do not have Peyronies disease for the following reasons you cite:
1.  Lifelong penile distortion, not recent onset
2.  Distortion when semi-erect or flaccid, not erect
3.  Occasional distortion, not constant or very frequent
4.  No mention of trauma
5.  No mention of familial PD or DC problem
6.  No penile curvature
7.  No pain

8.  No mass or lump, apparently; these can be missed even with PD, but in many cases the scar or plaque is easily found.

Please go to a good urologist and get to the bottom of your problem.   TRH

Where can I get the diet for treatment of Peyronie’s disease?

Where can I get the diet that you recommend for treatment of Peyronie's disease?


That diet is available and is explained in detail in Chapter 5 of "Peyronie's Disease Handbook."  

You must remember that PDI recommends a broad base of treatment for PD, using a variety of combined external and internal therapies, with your food intake and how you eat as being a very important part of your overall therapy plan.  The PDI diet for Peyronie's disease is only a part of the overall effort to increase your natural ability to recover from PD.  This suggests that you not rely on any one type of treatment but that you employ them all for best results.    TRH

Does Lexapro cause Peyronie’s disease?

i have been taking lexapro for about 7 months now – a side effect was diminished sex drive – so, as a result, my partner and I have had sex perhaps twice in those 8 months, ad that was nearly 6 months ago. I have been trying to stimulate myself so we can regain our sex life, modest as it is a this age and, of the last three occasions, i was able to get an strong erection but noticed now my penis is significantly curved upward – needless to say, i feel a bit freakish, and a conflicted between wanting to get aroused but not wanting to see my bent penis. Is it possible to Lexapro had this affect? I am 55 and now feel a "hate" relationship with my penis and not wanting to tell my partner or even have him see it. Basically, i am miserable about this and wanted to know if there is something i can do to help to "straighten out "my boy" and get back to more normal life (also looking to get off the lexapro but my Dr. said not till next year.


There are many side effects of Lexapro.  The most common are:   Constipation; decreased sexual desire or ability; diarrhea; dizziness; drowsiness; dry mouth; headache; increased sweating; light-headedness when you stand or sit up; loss of appetite; nausea; stomach upset; tiredness; trouble sleeping. 

There is no report in the literature of Lexapro causing or leading to development of Peyronie's disease

Before you go off in the wrong direction I advise that you have a medical examination to determine if you have Peyronie's disease.   If it turns out that you do indeed have Peyronies that your problem started in a more traditional manner of trauma.  A more likely scenario is that while taking Lexapro, or even before starting to take Lexapro,  you sustained injury during sexual activity that resulted in damage to the shaft of the penis.   Please review the information found on this site about Alternative Medicine treatment of Peyronie's disease.  TRH

Peyronie’s treatment diet questions

Diet questions
1. is rice milk an acceptable alternate?
2. why no bananas?


Yes, rice milk is an acceptable alternative drink, and so is almond milk. 

Bananas are to be avoided while doing self-treatment of Peyronies disease for reasons related to ancient oriental principles of yin-yang theory.   As I mentioned in “Peyronie’s Disease Handbook,” if you really want to completely understand why bananas should be avoided you will have to read several acupuncture text books to develop an Eastern insight into this way of looking at things.  The answer is not a simple Western explanation.    TRH  


Any institute located in India that provides treatment of Peyronies disease?

Hello Doctor,

I wish to know that is there any institute located in India which gives treatment for Peyronie.

With regards,


Greetings Rajan,

I am not aware of any formal group or effort in India to treat Peyronie's disease

The Peyronie's Disease Institute is the only online effort to educate, treat and research this problem.   You can read and learn about Peyronie's disease treatment online and in the two books I have written and undergo an active self-directed treatment plan based on the information and ideas found on this website.   If you have questions or concerns during the course of your treatment you are able to write me emails so I can share with you my experience and suggestions for help.   Usually men are very pleased and satisfied with this arrangement since they have come to learn that their own effort and interest is far better than what they receive from the average medical institution.  TRH

How do I develop synergy to treat my Peyronies disease?

Been searching your site, have ordered Neprinol, but have not found the alternative product suggested for the synergy 'maybe' needed — besides Vitamin E, which I take.


Please read this page from the PDI website, "Synergy and Treatment of Peyronie's Disease."

In this discussion you will learn that synergy results from the combined use of several different therapies, but not any particular therapies.   For successful Peyronie's disease treatment the more therapy and wider variety of therapy products that are used, the deeper and more effective your synergy will be – the more the merrier.

Synergy is a natural reaction when groups of similar things are combined.   Let's take for example people.    If we combine a group of people who are slightly bad, when they get together they will tend to do things and behave in a way that is generally more bad than they would if they were not together.   In a similar way,  if we combine a group of people who are good, when they get together they will tend to do things and behave in a way that is generally better than they would if they were not together.  I suppose you can say that by combining similar things the natural tendency of those things is intensified. This is synergy. There is no limit to the number of things you can add for synergy to happen, and everything seems to be affected by it so you can use any Peyronie treatment you want to cause it to help you.

In the Alternative Medicine treatment of Peyronie's disease we  use different therapies that have been shown to be slightly effective as a Peyronie's therapy.  But when you combine them – the more the better – you get an increase of this ability to reverse  the Peyronies problem.

Further, since no one can tell which of the Peyronies therapies you need most and which you are lowest in, we approach treatment from a broad base that you supply all of those that could be helpful so that you are not missing any and this will also strengthen the effect of synergy on your problem.  Let me know if you have any more questions about the Alternative Medicine treatment of Peyronies disease. TRH

What do I start doing to prevent my Peyronie’s disease from getting worse?

I was just told last week that I have pd..I have some pain that is light, no curving, but my erections are weak on the left side at the base with some mild ED. What do I start doing to prevent it from getting worse?  I saw my urologist who told me to take vitamin E 1000 IU daily.  Please advise me to help it not get any worse…thanks

Larry Baldwin

Greetings Larry,

I have never seen vitamin E by itself help anyone with Peyronie's disease.  Vitamin E is a great therapy but it must be combined with a variety of other therapies to make a positive and helpful impact on a difficult problem like PD.  Besides that, you cannot just take a general or lesser grade of vitamin E and expect it to work for you;  a pharmaceutical grade is required.  PDI has two great therapeutic grades of vitamin E available on the website.

You should by reading about Peyronie's disease on the PDI website, especially starting with the page "Start Peyronie's Treatment."  

When you have a specific question about treatment of Peyronie's disease please let me know.   TRH

Would Neprinol work on my Peyronie’s disease?


I've had Peyronies now for roughly 10 years. I passed a kidney stone in my 30's and it jammed at the end of my urethra, I squeezed it ,and it passed. But for a month my penis killed me. It eventually shrunk to about 3 inches, from 7  1/4 inches . Ive tried everything. I went all natural. vitamin c, 1000mg , omega 3 1200mg, vitamin e 1000 mg, l-arginine, ginkgo biloba, saw palmetto 1000mg, and flax seed oil, 1000mg gotu kola.  All have helped get at least 6 inches in length back after 10 years.

My love life suffered at first, but we overcame things. I would like to get the other 1 1/4 inches back. Right at the tip, just behind, it curves up around 30 to 35 deg. I can feel the hard plaque still. It just won't soften up any more.

Would Neprinol work, or do you have any suggestions on how to finally rid my self of this man destroying dilemma?  I'm 45 now, I would like to keep going if you know what I mean.

Thanks.  Any suggestions would be a great help.


While I realize you have probably just discovered the Peyronie's Disease Institute website on the internet, my first suggestion is that you stop playing around using different herbs and supplements that have not been shown to be helpful for treating PD.

"Going natural" is not the key to successful Peyronie's treatment; you have to use the right products and use them in the right way.  It looks to me like you just started using anything that might have had some positive things written about it, and hoped it would help your problem.   You have not "used everything."   You have only scratched the surface.   You have approached your problem from the wrong direction and gotten lucky that some of the things you did  might have helped you.   Had you spent that same time, effort and money using the products from the PDI lineup for your Peyronie's treatment I believe you would have been far better off today.

I suggest you get on at least the PDI medium plan along with the PDI gentle Manual Penis Stretching CD video and use them faithfully for a few months.  It is important to use the exact therapies from PDI because not all brands of Alternative Medicine therapies are of the same quality or potency.   You cannot walk into the average vitamin store and expect to get good quality products that will do the job for you.  It is amazing and appalling that many vitamin shops sell such low quality items.

Your question about Neprinol shows that you do not understand how to use Neprinol and that you are again approaching your therapy from the wrong direction.   You need to spend more time reading what is on the PDI website to learn how to go about successful Peyronies treatment. 

When you order from PDI you will receive specific instructions how to use everything that you order for the best possible treatment of Peyronies disease.   Let me know if you have specific questions about helping your problem.   Good luck to you.   TRH   

What is the best Peyronie’s treatment?


I am from Dubai.  My problem is like this:   Peyronie's disease with left lateral (side) penile curvature and constrictive ring deformity causing hourglass close to body. No pain up to now during sex.  I find that my penis  is now shorter by more than one inch.   I took vitamin A & E but it did not help.  What is the best Peyronie's treatment?   Thank you.

Greetings to you in Dubai,

I am sorry to learn about your problem.   

Taking only vitamin A and E is seldom effective because it is much too limited or narrow in its attempt to help you heal the PD scar.  The best Peyronie's treatment is not any one therapy, but a combination of several – sometimes many therapies that work to assist your ability to remove the foreign Peyronie's plaque or  scar tissue from your body.

Please do not think my answer is silly or insensitive.  Allow me to give you an answer that will tell you exactly what you need to do create the most effective therapy plan for your condition:  The best plan to treat your Peyronie's disease is the one that you create that causes your body to break down and absorb the foreign scar material.   The best Peyronie's treatment plan appears to be different for each man.   I do not know what you need to do to make this happen, but I can tell you how to figure this out for yourself. 

If you follow these steps you will do as much as you possibly can to be successful over your Peyronie's problem:

1. Learn as much as you can about the natural treatment of Peyronie's disease from the PDI website.  The more you understand the better your treatment and your results will be.

2.  Go to "Start Peyronie's treatment" to see the basic outline of getting started with care.  Follow those instructions your read about.  

3.  Determine the size, shape, density and surface features of each PD scar you can find.  If you do not know how to locate your PD scar(s) send me an email and I will give you special help to determine where it is located and how to evaluate it.  This information is critical since you will use it to measure the progress and effectiveness of your Peyronie's treatment plan.  Without this information you are only guessing about your treatment. 

4.   Monitor your PD plaque for changes as you follow your treatment plan.   If your scar or plaque changes size, shape, density or surface features while you are using your treatment plan, there is no need to change it; you simply continue to use that plan for as long as your scars continue to reduce. If your  scar DOES NOT CHANGE size, shape, density or surface features while you are using your treatment plan, you must increase the plan by either increasing your dosage of therapy products or increasing the variety of treatments you are using.  When you get to that point I will offer you ideas and information so you will know how you wish to proceed. 

Please let me know if you have an questions about how you wish to proceed.   TRH

Pentoxifylline, Niacin and Peyronie’s Disease

Pentoxifylline is not an approved Peyronie’s disease drug

There are several things I find interesting in a question and answer about Peyronie’s disease and Pentoxifylline (Pentox) I discovered online recently.  It appears on the Peyronie’s forum of a medical doctor who is well known as a Peyronie’s disease expert.  I will not use the doctor’s name since it does not serve a useful purpose to mention his name.

Here is the question, followed by the doctor’s answer:

Question:  Can Pentoxifylline help with increasing blood flow when a man has PD?  Also is Niacin also an alternative that might achieve any results?

Answer:   Pentoxifylline has been shown in animal studies to potentially reduce the development of the Peyronie’s scar when the animals consumed the Pentox in their drinking water from the time that the Peyronie’s process is triggered.  Pentoxifylline is indicated to enhance blood flow to the lower extremities in patients with peripheral vascular disease likely because it has a mild non-specific vasodilating effect.  Therefore, it is possible that it can increase blood flow in the man with PD.  As to whether this will improve erections or has anything to do with preventing progression of already established PD is unknown.  Niacin, to my knowledge, has not been studied as a treatment for Peyronie’s disease.

Pentox preferred simply because it is a drug

Point # 1.  The doctor responds that the use of Pentoxifylline is used to treat Peyronie’s disease because it has the ability to enhance blood flow to the lower extremities in patients with peripheral vascular disease likely because of its mild non-specific vasodilating effect.

My response:  Here the doctor is saying that Pentoxifylline is used in Peyronie’s disease because it improves blood flow in people who have peripheral vascular disease.  Anyone who has studied this subject knows that Peyronie’s disease is not a vascular or blood vessel disease, so it is difficult to understand from this answer the connection between the two conditions. This reason he gives for using Pentox for treatment of PD is not supported by what we know about this condition.

Point #2.  The doctor states that Pentoxifylline is used in Peyronie’s disease (of the penis) because it improves blood flow in the periphery of the body, meaning arms and legs.

My response:  These are two different areas of the body. This part of the answer suggests that Pentox has not been tested or shown to actually improve the blood flow to the penis, only the upper and lower extremities.  This reason he gives for using Pentoxifylline for treatment of PD is not supported by what we know about this condition.

Point #3.  The doctor attempts to tie his two points together and then carefully speculates that “it is possible that it can increase blood flow in the man with PD.”

My response:  What the doctor is saying is that using Pentox for Peyronies treatment might possibly work since it works for other conditions that are only remotely related. This kind of speculative use of a drug is common, and would not be objectionable except for the fact that Pentoxifylline is known to have side effects that can affect the cardiovascular, immune, digestive, respiratory, visual and nervous systems. That is a risk taken by a patient for use of a drug that might only possibly help an unrelated condition.  I doubt many patients know that they are exposing themselves by taking drugs that are not known to help the condition they have.

Point #4.  The doctor reports that it is unknown if Pentoxifylline will improve erections or has anything to do with preventing progression of an existing case of Peyronie’s disease.

My response:   Saying that it is unknown if Pentox will improve erections suggests that it does not influence blood flow to the penis. Yet, improving penile blood flow is one of the reasons given by this doctor to justify using it for Peyronie’s disease.   Since I have never heard of anyone taking any medication for prevention of Peyronie’s disease, the doctor also says that Pentoxifylline will not alter the progression of a case of PD once it has started.  This sounds to me that it would not help Peyronie’s disease.

Point #5.  The doctor reports that to his knowledge niacin (a member of the B vitamin family) has never been studied as a possible treatment for Peyronie’s disease.

My response:  Niacin is well known to those who take vitamins for the “niacin flush” that it causes.  Niacin causes an increased blood flow throughout the body, experienced as heat, redness and itching that occurs after taking a few hundred milligram dose.

So we have the doctor reporting that Pentox (with side effects) is used to treat Peyronie’s disease because it has a “mild non-specific vasodilating effect,” yet niacin (with no side effects) which also has a mild to moderate non-specific vasodilating effect has never been studied as a Peyronie’s treatment.

I think this is a classic example of the drug industry ignoring potential non-drug therapies simply because they lack profitability.  This is a point to remember when you are told that no nutritional therapy has been shown to help PD.   This is only true because these companies refuse to do the testing to prove they might have merit.

Point #6.   The doctor uses  only one brief  sentence to discuss niacin, and 90% of his reply to discuss a drug that does the same thing as niacin can do and do it without side effects.  In his short sentence about niacin he only says that it has not been studied as a Peyronie’s treatment.  Period.  As a scientist, as a physician interested in advancing the body of thought about Peyronie’s treatment, wouldn’t you think the doctor would be more interested in something like niacin?  Instead, he merely brushes the idea of niacin use for PD aside.  This is so typical of the attitude of organized medicine about treatment of Peyronie’s disease.

Point #7.  The man who asked a reasonable and intelligent question about niacin was not given an actual answer about niacin.    He was only given a reply that promoted the use of a drug that has side effects and not known to be effective against Peyronie’s disease.   And you wonder why men get frustrated with the lack of help and useful information about Peyronies treatment.

Disorders of the Penis besides Peyronie’s Disease

Penile conditions, other than the curved penis of Peyronie’s disease

There are additional problems of the penis that can develop while a man treats his Peyronie’s disease.  There are not many additional problems, but all can complicate your life more than you need at this time.


Priapism is a persistent, often painful erection that is not associated with sexual activity and is not relieved by orgasm, lasting from a few hours to a few days.  In priapism blood enters the penis but does not leave, thus the erection is maintained.   The more common causes of priapism:

  • Penile injections, as verapamil, collagenase, steroids or interferon-alpha-2b
  • Drugs, such as anesthetics, antidepressants and blood pressure medications
  • Alcohol or drug abuse, especially cocaine
  • Spinal cord disease
  • Injury to the genitals
  • Blood diseases, including leukemia and sickle cell anemia

Rapid treatment for priapism is important, even without Peyronie’s disease present, because a prolonged erection can result in tissue destruction by reducing blood flow and lead to scar formation. Treatment involves removing trapped blood with a needle placed in the corpora cavernosae, as well as treating any underlying medical condition or substance abuse problem that might be present.


Balanitis is an inflammation of the foreskin, or skin covering the head of the penis.   Symptoms are redness, swelling, itching, rash, pain and a foul-smelling discharge in the area of the foreskin.   Balanoposthitis is a similar condition in which the glans (penis head) and foreskin are inflamed and present similar symptoms.   Both problems can occur in men or boys who are uncircumcised (foreskin has not been surgically removed).  If an uncircumcised male does not wash under the foreskin regularly, then sweat, debris, urine, dead skin cells and bacteria will collect under the foreskin and cause irritation.    Other common causes include:

  • Infection – local or systemic infection with candida albicans, the yeast responsible for thrush, can result in an intensely itchy and scaly rash.  Several sexually transmitted diseases (STD), gonorrhea, herpes and syphilis can also produce balanitis in addition to their unique infections that affect other parts of the body.
  • Dermatitis/allergy Dermatitis is any inflammation of the skin often caused by contact with an allergen or irritating substance. Sensitivity to even a small amount of certain chemicals in  soaps, detergents, perfumes and spermicidal preparations can cause balanitis.
  • Diabetes – When a diabetic has glucose (sugar) in the urine, this can be trapped under the foreskin and acts a rich breeding medium for many bacteria.

Treatment of balanitis depends on determining the underlying cause, improved hygiene and perhaps  circumcision if the balanitis cannot be controlled in any other way.

Phimosis and paraphimosis

Phimosis is a medical problem in which the foreskin (prepuce)of the penis is so tight, preventing it from being pulled back or retracted from the head of the penis.  Paraphimosis is a medical emergency in which the foreskin is stuck, after being rolled back or retracted, and cannot be slid back to its usual position over the head of the penis.

Phimosis is most often observed in children, and may be present even at birth.  When it occurs in an adult male it is usually caused by an infection of the reproductive tract, or scar tissue that formed as a result of injury or chronic inflammation of the prepuce.   Phimosis can also be caused by balanitis when it causes the foreskin to the scarred or tight around the head of the penis.  Immediate medical care is required if phimosis makes urination difficult or impossible.

Paraphimosis is a medical emergency because serious complications can arise if it is not treated. Paraphimosis may occur after sexual activity, a nocturnal or typical daily erection, or after trauma to the head of the penis, leading to pain and swelling, and impair blood flow. When extreme, this reduced blood flow can result in death of the penile tissue (gangrene), making amputation of the penis necessary.

Treatment of phimosis may only require gentle manual stretching of the foreskin repeated daily over a period of time.  Circumcision is often used to treat phimosis.  When the phimosis has gone on a long time the prepuce sometimes adheres to the glans.  When this happens, a surgical procedure called preputioplasty is used to separate the foreskin from the glans.

Treatment of paraphimosis focuses on rapidly reducing the swelling of the glans and foreskin, using ice and pressure applied to the head of the penis. If these simple measures are unsuccessful, an injection of medication can be used to drain the inflammation and blood from the penis, or small cuts in the foreskin are made by a surgeon to release the prepuce from behind the glans.

Penile cancer

Penile cancer is a rare form of the disease.  While the exact cause of penile cancer remains unknown, certain risk factors for cancer are known, including:

  • Phimosis – Tight foreskin that is constricted and difficult to retract, discussed above.
  • Uncircumcised penis – Men who are not circumcised are at higher risk for cancer of the penis.
  • Smegma – Natural oily secretions from the skin of the prepuce can accumulate if not cleaned daily.   If allowed to collect under the foreskin, this results in thick, cheesy white, bad-smelling substance, known as smegma.   Smegma by itself is irritation to the prepuce and lead to inflammation and a host of other problems.
  • Human papillomavirus (HPV) infection – More than 70 types of  human papillomaviruses can cause warts (papillomas).   Only a few of these HPVs infect the reproductive organs and the anal area, being passed as a STD from one person to another.
  • Smoking –Cigarette smoking brings many cancer-causing chemicals into the blood stream  that affect more than the lungs.
  • Psoriasis treatment – The medication and ultraviolet light used to treat can cause penile cancer.
  • Age – Penile cancer occurs most commonly in men after age 50.

Common symptoms of penile cancer are sores or unusual growths on any area of the penis, abnormal discharge from the penis, and bleeding.  Surgery or radiation is commonly used to remove the cancer from the penis.

Since 2002 PDI has advocated Alternative Medicine Peyronie’s treatment options to avoid any of these complications that compromise penis health.

Penis Doctors or Peyronie’s Doctors? – Take Your Pick

Doctors who specialize in Peyronie’s disease

When you think about going to a “Peyronie’s specialist,” you should understand a few things that could make all the difference in the world to you.  You should also know that Alternative Medicine is your safest and most logical approach to Peyronie’s treatment – more about that at the end of this article.

Each month I am asked for the name of a few Peyronie’s doctors; someone who specializes in the treatment of Peyronie’s disease, in a particular part of the country or a specific city. My answer that I do not know of any such doctor always seems to be a surprise.   Often a follow up question is posed in which I am then asked for the names of penis doctors, and again I give the same answer.

For anyone interested in finding a Peyronie’s doctor, first consider that Peyronie’s disease is known as “the doctor’s nightmare.”   Notice, the name is not “a man’s nightmare,’ or “a curved penis nightmare,” or “a patient nightmare,” but “doctor’s nightmare.”   This suggests how much doctors in general do not like dealing with Peyronie’s disease.  The average doctor does not like to deal with the diagnosis and treatment of Peyronie’s disease, as well as the many valid complaints and exaggerated demands of both the men and women who must live with this problem.  Frankly, we men with Peyronie’s disease are often a royal pain in the butt for an MD to deal with.

Peyronie’s specialists

Most often it is the urologists who come closest to the idea of being penis doctors or Peyronie’s doctors.  But even they often want to avoid the many frustrations and long explanations that are a part of working with men who have Peyronie’s disease.  I guess that 99.4% of men who are given a diagnosis of Peyronie’s disease have not once ever heard of it before it is dumped on them.  That this condition exists is a total shock to the man who first learns he has the problem. And just like the denial phase of someone who learns of the death of someone, there is a denial phase when first being told that the reason for the penile curvature, pain, or strange lump is an interesting thing called Peyronie’s disease that has no known cause and no known medical cure – other than Peyronie’s surgery.   This news creates a lot of denial issues in the patient that the doctor must take the time to explain away.

It is said that no one is happy while dealing with Peyronie’s disease.  Another reason the doctor is not happy is because he or she has no standardized or accepted form of medical treatment to rely upon.  Generally, there are four three basic approaches for managing this problem medically:

  1. Offer no treatment, but simply monitor the progression of the problem. Suggest the patient come back in six months to determine if the problem has deteriorated enough to warrant the risks of surgery.
  2. Offer the patient to either “try verapamil or cholchicine or POTABA for a while, although I have not had much luck with any of them, or you can always use some vitamin E if you would like.”   This kind of low key and unenthusiastic recommendation is based on the fact that none of these approaches work, and the doctor knows it.  The MD is put in a tough position because he or she cannot help PD, and this is a known fact from the start.  Talk about a negative situation that only gets worse as the penis shrinks or sex becomes difficult as a curved penis develops.
  3. Suggest surgery right away.
  4. Go home, ignore it, and try to learn to live with it.

These four options all seem wrong to the thinking patient. Yet, the doctor feels obligated to offer some kind of treatment when none actually exists, and he knows ahead of time that the patient will be upset when nothing helps.  Long explanations, distrust, and complaints will follow over a few office visits until the patient figures out the doctor really has no Peyronie’s disease treatment. The doctor knows ahead of time he will look incompetent and non-caring no matter what he does.  Hence the term, “doctor’s nightmare.’

For all these reasons only a few medical doctors have focused on Peyronie’s disease treatment.  Some of those who work in this area of urology are:

Thomas Lue, MD – Los Angeles, CA
Culley Carson, MD – Chapel Hill, NC
Lawrence Levine, MD – Chicago, IL
Martin K. Gelbard, MD, Los Angeles, CA
Sudhakar Krishnamurti, MD – Hyderabad, India

These doctors are essentially using the same drugs as any general practitioner or urologist, with perhaps maybe the surgery they perform being different in some cases.   You need to understand that while these doctors can be called Peyronie’s specialists because they hold themselves out to being more interested in or spending more time in the area of Peyronie’s disease treatment and diagnosis, there is not that much different they can offer than the doctor down the street in your town.  The great difference with these doctors is the number of people they see who have PD, so they will have more experience in this area.

For this reason when some calls to ask about a Peyronie’s doctor, I suggest they just contact a local urologist they have confidence in and stick with him.

Since there is no accepted standard medical treatment for Peyronie’s disease, and so many doctors suggest not doing anything for the first 6-18 months, I strongly suggest that a person consider building up his own ability to heal and repair the Peyronie’s plaque or scar.  Information can be found at natural Peyronie’s disease treatment.

Diagnosis of Peyronie’s Disease

Poor welcome to the world of Peyronie’s disease

It seems that most men cannot clearly or fully understand the scope of the problem when they are first given a diagnosis of Peyronie’s disease.

Obviously, when a man goes to the doctor for the first time it is because he is having a problem of some type with “his plumbing.”   It might be the sudden or gradual appearance of pain, a lump or nodule, curved penis or distortion of some type, or reduced sexual ability, that brings him to see his doctor or surf the Internet. While he knows he is having a few Peyronie's disease  symptoms that were not there until recently, he is surprised to learn there is actually a medical condition that causes his problem.

After being given the diagnosis, a common first mental question often is, “If there is this problem that can so cruelly affect a man, why on earth have I never heard of Peyronie’s disease before today?

It has been recently estimated that after the age of 40, there are about four to six cases of Peyronie’s disease for every 100 men around the world.  That is a lot of men and a lot of cases of Peyronie’s disease.  For such a common condition, why is it that no one seems to know about PD until it is too late?

There are a few answers to this question, and they are all important to any man dealing with Peyronie’s disease:

  1. No one likes to admit he has a problem, or is less than perfect, when it comes to his sexual apparatus and his sexual ability.
  2. No one wants to the subject of teasing or to be pitied.
  3. There is often such social restriction limiting discussion of sexual matters that prevents open and free information that limits the discussion of Peyronie’s disease or similar topics.

This is indeed unfortunate because if there was more knowledge of Peyronie’s disease there probably would be less of it. Additionally, if there was more knowledge and comfort  discussing this problem we would probably be a lot closer to a genuine Peyronie’s treatment than we are now.

If more young men were given more information, such as how trauma is associated with the start of Peyronie’s disease in over half of the cases, it is more likely that reasonable caution and defensive measures would be taken.  It is very difficult to avoid a problem if you do not know it exists. This is why in “Peyronie’s Disease Handbook” I spend a fair amount of time describing how men should talk to their sons about this problem.

To learn more about Peyronie’s disease, please go to the Peyronie’s Disease Institute website for information about cause, progression and Peyronie's natural treatment.

Synergy and Treatment of Peyronie’s Disease

How Synergy Applies to Treatment of Peyronie’s Disease

Peyronies disease treatment forum blog of the Peyronie’s Disease  Institute, with Peyronie’s desease cure discussion
Learn the latest and best Natural Peyronie’s treatment

Synergy (sin’-er-je) is the interaction of two or more substances or forces that when combined tends to produce a total effect that is greater than the sum of the individual elements. A short explanation of synergy is “1 + 1 +1 = 5”. Taber’s medical dictionary defines it as “the harmonious action of two agents such as drugs, or organs such as muscles, producing an effect which neither alone could produce, or an effect that may result which is greater than the total effects of each agent operating by itself”.

Synergy can be applied to winning a game of tug-of-war, or to the treatment of Peyronie’s disease to reduce the terrible curved penis that so often develops.

Here is a very good example of synergy in everyday life. A doctor must closely monitor the combined effects of drugs that are prescribed to a patient. The effect of drug A on the body might be well known, and the effect of drug B might also be well known. But the synergistic effect of combining drugs A and B can be difficult to predict. As a result the doctor must closely monitor a patient when multiple medication is being administered. Thus, synergy is a significant part of the art of medicine.

There are many examples in life in which two or more agents or elements act in common to produce an end result that is greater than the simple sum each is able to achieve separately. A good example of synergy occurs in agriculture, when soil nutrients are applied to benefit crops. If nutrient A is known to produce a 2% increase in crop production, and nutrient B is known to produce a 2% increase in crop production, it is logical that using these two nutrients together should result in a 4% crop increase. However, because of the synergy between nutrients A and B a 6-8% crop production increase might occur, instead of the expected 4%. Taking it a step further, nutrients A, B, and C (with each increasing crop production by 2%) when used together might result in a combined synergistic effect above 12%.

Did you ever hear that some cooking recipes cannot be simply doubled if you want to make twice as much of a particular dish? Have any idea why that would be so? Sure you do: synergy. Perhaps, when a recipe is doubled, the oil, or the salt, or other ingredient reacts in a way that is more than twice its single effect. This is another example of synergy in action.

Let’s say that I can lift a maximum of 100 pounds, and you can lift a maximum of 100 pounds. It would seem reasonable that by working together, you and I should be able to lift 200 pounds. However, with the principle of synergy, it might be possible that together you and I could lift more than that, maybe 205, 210 pounds or more. Life is full of situations in which the synergy of team effort occurs.

Peyronie’s disease treatment using synergy

PDI’s philosophy for Peyronie’s disease natural treatment makes a lot of sense when you think about taking advantage of the power of synergy. We are suggesting that you take advantage of a simple and frequently seen phenomenon that occurs all around us every day. This explains why it is better to combine vitamin E with vitamin C and MSM or PABA in your Peyronie’s therapy plan.

Peyronie’s Disease Institute’s  approach of using multiple natural therapies uses this power and expects a synergistic result in treating PD, just as in other applications commonly seen in medical practice, architecture, agriculture, or any other part of life. The synergistic effect applies in countless areas and situations, and treatment of PD is no different. Therefore, the synergy of multiple therapies selected from successful PD research and studies should result in an improved ability of the body to heal and repair.

Science is Slow about Peyronie’s Treatment

Science Can Be Slow – Especially with Peyronie’s Treatment

It is said that if aspirin was discovered today, it would not meet the rigid and exacting standards of scientific proof that are currently in use. Aspirin would be one of those drugs that would be outside of accepted medical practice since it would lack sufficient scientific proof.

Medical acceptance and scientific proof of a therapy is, of course, important and desirable especially with Peyronie’s disease treatment for the elimination of the classic curved penis or other penile distortions that occur.  Yet it is important to keep in mind that just because a procedure or substance lacks this acceptance does not mean it is therefore ineffective or inferior. It might just mean that medicine and science have just not yet figured it out sufficiently to declare that it is OK.

Remember that it was not too many years ago medicine and science said the following were falsehoods, and could not be proven scientifically: 1. Exercise is good for your heart. 2. Diet is related to heart disease. 3. Smoking causes lung cancer. 4. Smog is harmful to lung tissue. 5. High fat diet raises cholesterol in the blood. 6. Antioxidants, vitamin E and vitamin C are related to immunity and resistance. This list of what science made mistakes about could go on for a long time, all the way back to the “The world is round”. Most of us are old enough to remember the problem with Thalidomide. How about the AMA declaring that there was “insufficient scientific proof” of a correlation between a high fat diet (think French fries) and obesity?

The point is simple:  Sometimes science is just slow to pick up ideas and information that are apparent to average people who use common sense and simple observation.  PDI thinks the same is basically true in regard to Peyronie’s disease natural treatment.

Peyronie’s Disease and Baby Boomers

Peyronie’s disease: male health problem no one knows about

If you are a member of the baby boomer generation and have never heard of Peyronie’s (pay-row-neez) disease, you are not alone. However, if you are a male baby boomer or married to one, you are in the prime age group to experience a problem you know nothing about. This is so because Peyronies disease primarily affects men between 50 to 65 years of age, although an age range of 18 to 80 years has been reported, with an average age at onset of 53. Few people know about the problem until they need Peyronie’s disease treatment. This is why it is important for all baby boomers to know about, and how to avoid, it because this health problem can easily ruin your life. Peyronie’s disease remains one of the most perplexing and difficult urological diseases to treat; it has been called “the doctor’s nightmare”. Most everything about this condition (cause, progression, symptoms, age distribution, response to treatment) is variable and unique to the man who has it. The great variability of Peyronie’s disease that makes it difficult to study and to understand, also makes it almost impossible to treat like other medical conditions. It is a complex problem that is much more common than most people realize. Estimates suggest that up to eight out of 100 men over the age of 40 have Peyronie’s disease – that is a lot of people worldwide – and still only a small percent of people have ever heard of it. People are reluctant to discuss this problem because it involves the male organ. For this reason it is difficult to develop accurate information and statistics, especially since men are so shy on one hand, yet also inclined to exaggerate.

Definition of Peyronie’s disease

Peyronie’s disease can best be understood as an exaggerated wound healing in response to an injury in which an excessive amount of Peyronie’s scar tissue develops within the man’s shaft. Peyronie’s disease (also known by over 12 different names, among which is “iduratio penis plastica”) is very special disorder of the connective tissue in which fibrous “scars” or “plaques” develop usually after direct injury. This Peyronie’s plaque occurs in a special tissue of the shaft known as the tunica albuginea, a fibrous chamber or envelope that surrounds the two penile cylindrical shaped masses of spongy tissue known as the corpora cavernosa. The corpora cavernosa enlarge during sexual excitement, and the tunica albuginea covering, are designed to expand and elongate. If there is fibrous scar or plaque material in the tunica albuginea, the expansion and elongation cannot develop properly resulting in bending, weakness, shortening and incomplete filling of the organ. Sometimes this distortion is mild (just a few degrees) and does not affect the ability to perform, while at other times the distortion can be extreme (more than 90 degrees) resulting in greatly adverse consequences. A certain degree of normal penile curvature can and does occur in some men. This is a benign and natural condition many men are born with, commonly referred to as congenital curvature; this is not Peyronie’s disease.

Peyronie’s disease signs and symptoms

Four common findings of Peyronie’s disease:

  1. Pain – caused by inflammation and stretching of internal tissues in response to injury and distortion; can be present constantly or only during erection
  2. Nodule or mass formation – variable size lumps or elongated cords can develop in one or multiple areas; sometimes these are difficult or impossible to locate depending on the density, depth and size of the scar formation
  3. Curvature or distortion – caused by presence of one or more nodules or masses of scar tissue in the tunica albuginea, preventing normal expansion during erection; can be minor to gross in appearance
  4. Reduced sexual ability – due to physical distortion that prevents penetration or due to reduced firmness that also prevents penetration (erectile dysfunction).

The onset of Peyronie's disease symptoms can be sudden or slow, but often appears within a month or two after direct injury. The pain of Peyronie’s disease is extremely variable; from hardly noticeable to the kind of pain that prevents sleep. Peyronie’s pain is worse in the beginning, usually gradually improving over time – improvement in a few weeks while others continue for years. For these reasons Peyronie’s pain is not a reliable way to judge the severity or calculate the time for eventual recovery. Even though Peyronie’s disease is a male health problem, women are also affected by it. They are indirectly and adversely affected by the erectile dysfunction, organ curvature and distortion that make intercourse often impossible, as well as loss of organ size that often occurs over time. Additionally, and perhaps even to a greater degree than men, woman bear the brunt of the mood swings, anger, brooding and ill-temper that accompany their partner’s Peyronies problem.

Treatment of Peyronie’s disease

There is no standard or accepted medical Peyronie’s cure since no drug is proven to eliminate the scar within the shaft. The only accepted and available medical treatment is Peyronie's disease surgery. However, given enough time after Peyronie’s surgery the condition will only re-appear in a worsened presentation. This surgical outcome is made bleaker by knowing that even the first Peyronie’s surgery can result in total loss of sensation (anesthesia), increased pain and increased curvature and greater scar formation than before surgery, and in some cases amputation. The Peyronie’s Disease Institute has specialized for the last eight years in the use of Alternative Medicine therapies and techniques that are found to be successful in perhaps 60-80% of cases. None of the therapies are known to result in adverse reactions or side effects. For more information about the Alternative Medicine approach, visit Peyronie’s disease treatment.

Prevention of Peyronie’s disease

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With so many variable aspects of this problem to consider, it is important to know that in addition to everything else, there is no universal agreement about the cause of Peyronies. Some say that injury alone cannot start the problem as we have described above, but that other genetic and metabolic factors must also be present. The Peyronie’s Disease Institute takes the position that this is true. However, if a man never sustains direct injury to the area he is far less likely to develop Peyronies. With age not working in the favor of any baby boomer couple, it is important to evaluate all situations in which direct injury can affect this area – especially sexual activity. This requires that special caution is exercised if a baby boomer gentleman finds he no longer has the usual firmness he previously possessed (erectile dysfunction). Attempting intercourse with a partially flaccid organ can result in sudden buckling or abrupt bending during insertion or the sex act itself. Another way to prevent injury is to modify the techniques used during sexual relations. The single most common injury that starts Peyronie’s disease occurs when the female partner is on top, and she loses hold of him while she thrusts down, jamming and painfully bending him against her upper thigh. To avoid this kind of injury it is important to not use any female-superior position, but to use other techniques in which physical contact is controlled, firm and not likely to disengage during activity. Even if baby boomers have never heard of this terrible condition that robs a couple of one of the greatest pleasures of life, it happens every day. Now that you know about Peyronie’s disease you can do a lot to protect the best years of your life. Dr. Theodore Herazy has practiced Alternative Medicine for over 40 years, and has directed the Peyronie’s Disease Institute for the last eight years. He has written two books about this problem, “Peyronie’s Disease Handbook” and “Peyronie’s Disease and Sex.”