Can I take these other vitamins with my Peyronies treatment plan?

My husband has just started the medium plan and is working on the diet modifications. I am joining him on taking the Vitamins A and C for the health benefits. We want to know if you know of any adverse interactions that are likely to happen with our current additional use of Magnesium Citrate, Krill Oil, CoQ10, and Niacin along with the products in the medium Peyronies treatment plan.

We have been pouring over the Peyronies Disease Handbook and really appreciate all the detail there.



As long as you take the PDI directed plan as suggested there should be no adverse reaction wit the various nutrients that you list here. 

Thank you for the kind comments about "Peyronies Disease Handbook."    People always find the book extremely helpful and are surprised at the depth of information, especially after being told by most people that there is little that can be done to help this condition.   TRH

Used PDI treatment to cure his Peyronies disease, now wants to do the same for a topical scar.

I was a customer a few years ago and cured mostly my Peyronies scar through your plans. My penis is mostly back to its normal form now and painless, and that is good. My question today is concerning a topical scar, not a scar on my penis. I have a long rubbery keloid scar on my forearm which keeps slowly snaking it's way down my arm year by year. And before trying to have it frozen off I'd like to try your enzymes and CP Serum and such.

I would like to know which enzymes of yours to try first? The Quercetin/Bromelain combo or just the new 5000 Bromelain? And the Copper solution with DMSO? Also, have you heard any research on Lugol's solution and iodine concerning topical scars?

Thank you for your time.



Glad to hear your feedback on your successful results following the PDI concepts of Peyronie's treatment.  You really should write back to this same Q/A section and provide some insight and experience you gained while successfully treating your Peyronie's disease.

I have had many men tell me over the years that they have used a very similar scar treatment plan that follows their PD plan.  I do not have much feedback from these men about scar treatment but that idea makes sense to me.  Let me know what happens for you.  TRH

Can I follow a natural Peyronies treatment plan while being on several different medications?

Dear Dr. Herazy,
I have been diagnosed with Peyronie's disease, but I also have some other health issues that I am being treated for. I want to know if any of the substances used in your PD treatment will interact negatively with my current prescription medications. I am taking 1 Levothriod tab 88mcg on an empty stomach, for my thyroid; 1 Sulfamethoxazole/Trimethopr at bedtime ( I have an Atonic bladder and must self catheterize every time I urinate); I also take 1 Acyclovir tab 400mg twice daily for herpes prevention. I think my herpes outbreaks contributed to the development of my PD. I want to start treating my PD because, as per your website, my Urologist tried me on Verapomil ointment, but it irritated my skin, and he has't been fortcoming with any other treatment ( wait and see). I also have BHP, and he is watching my PSA levels, (I have had three biopsys, all negative. Thank you for any information on my question.


Greetings Lou,

Sorry to hear of your current situation.

The best answer I can give you is in two parts. First, no one in over ten years of this work has reported a drug interaction occurrence as a result of taking any natural Peyronies treatment product.  These are all naturally occurring substances, for the most part nutritional in nature.  There would be little reason to think that any medication would have an adverse reaction with a nutritional product.  Second, I suggest you present the list of therapies that you decide to take as an Alternative Medicine treatment for Peyronie's disease to the medical doctor who prescribed these drugs to you.   He can offer his opinion about the appropriateness of combining these two different forms of treatment.    

Is this Peyronies disease?

I have 0 pain, 0 curve in erection and no hourglass look in erection.

However I am 18, and have had ed for 4 years. For as long as I can remember, on the occasion, My flaccid penis has a bit of the hourglass look. Also when it is night time, and I am extremely relaxed, and my flaccid becomes bigger, and almost a semi erect, it occasionally curves to the right which i just started noticing about 6 months ago. Also, after I urinate, occasionally I see my penis begin to curve right.

Again no pain, no bumps, no hourglass or curve in erection

I only see hourglass/curve in flaccid/semi erect.  Is this Peyronies disease?  If so will it get worse?  Can I send pictures to you?



Pictures would be of little help to reach a conclusion.

No one can say with any level of certainty based on the information you have provided whether your condition is Peyronie's disease or not.  These things are not diagnosed so casually or easily.   To know for sure what is happening, you must see a urologist and be examined for a formal diagnosis.

Having said that, it is my absolute guess that you do not have Peyronies disease for the following reasons you cite:
1.  Lifelong penile distortion, not recent onset
2.  Distortion when semi-erect or flaccid, not erect
3.  Occasional distortion, not constant or very frequent
4.  No mention of trauma
5.  No mention of familial PD or DC problem
6.  No penile curvature
7.  No pain

8.  No mass or lump, apparently; these can be missed even with PD, but in many cases the scar or plaque is easily found.

Please go to a good urologist and get to the bottom of your problem.   TRH

What is the difference bewteen the two vitamin E products you use for Peyronie’s disease treatment?


I was wondering about these two products:  Vitamin E Factor 400/400 and the other is  Maxi-Gamma E.

I am probably not understanding this correctly which is why I am emailing, but they seem to both be vitamin e.   Is that correct?   If so why take both? I would be taking too much vitamin e if I take both.   If I am not correct could you explain the difference.

Thank you


Greetings Carl,

Yes both are vitamin E products.   But, vitamin E is not one thing; vitamin E is actually a family of eight different but related fat-soluble compounds that exist in diverse forms, all widely found in the plant kingdom. There are two basic groups of vitamin E, the tocopherol family and the tocotrienol family; each of these two forms has four subdivisions called alpha, beta, delta and gamma, for a total of eight variations or forms of vitamin E.    Different forms of vitamin E are found in different parts of a plant; the green parts of a plant contain mostly alpha tocopherol and the seed germ and bran contain mostly tocotrienols.

The product Vitamin E Factor 400/400 is very unique in the world of nutrition because it contains a large amount of all eight members of the entire vitamin E family for broad based support of this important vitamin group. 

The product Maxi-Gamma E is also unique because it primarily contains gamma tocopherol, the one member of the vitamin E family that is most responsible for soft tissue healing hence its importance to Peyronie's disease treatment.   

PDI makes both of these products available – and most men who follow a successful PDI Peyronies treatment plan will use both products  typically taking one of these in the AM and the other in the PM.

Why do you think that taking both would be too much?   Overdosing with vitamin E occurs at a relatively low dose only when synthetic vitamin E is taken.  PDI only supplies natural forms of vitamin E that are organic.  Please see this article   Peyronie's Disease Treatment and Vitamin E for a discussion about the silly vitamin E scare that is going around simply because people do not understand the story behind vitamin E.  You will understand the background of how poor research and bias maligns even a naturally occurring vitamin that is essential for health.

Unfortunately most vitamin E supplements contain only alpha-tocopherol. This information should make it all the more obvious why a Peyronies disease victim needs to carefully choose supplements that contain the complete vitamin E family of tocopherols plus tocotrienols and any that are  especially rich in gamma-tocopherol. Like all families, each member has certain strengths and abilities, requiring a variety of workers to support the necessary tissue changes needed to improve the health and resistance of tissue damaged in PD. Here is a list of the eight forms of vitamin E:

Tocopherol group


Tocotrienol group


Each of the two forms has its own area of use or activity in the body. The tocopherol forms function as strong antioxidants, with the alpha form being the most active of the four subdivisions. Vitamin E, like all antioxidants, protect at the cellular level against the effects of potentially damaging by-products of metabolism, called free radicals. A free radical is a molecule that has been involved in a chemical process in the body, and in so doing becomes unstable when it loses an electron. Free radicals can cause cell damage by attracting electrons from stable molecules in other areas in the body, thus making additional cells also unstable.

Unless they are connected to an antioxidant, highly unstable free radicals attack the polyunsaturated fatty acids of cell membranes in a chain reaction. This process of losing and gaining electrons might contribute to the development of heart disease, cancer; Alzheimer's disease, arthritis, premature aging and cataracts and even excess scar formation.

Peyronie's and vitamin E connection

The tocotrienol form of vitamin E has shown superior action in maintaining arterial health because of its ability to reduce plaque and fibrous tissue infiltration in damaged arterial walls. This same ability is suspected to result in reduction of scar and fibrous tissue buildup in other parts of the body.

Vitamin E has 75% worldwide approval as a first-line treatment of Peyronie's disease, yet its effectiveness has not been proven to scientific standards. It is the most popular of the alternative treatments used. Vitamin E is perhaps the most researched and tested of the alternative methods for treatment of PD, and yet it has not been researched or tested very much. It has been heavily researched and tested for other health conditions that have the same or similar scar and fibrous tissue formation, and it has proven its effectiveness. Use of vitamin E is based not only on the positive results it gets with Peyronie's disease, but also the positive results scored against other health conditions similar to it.

Maybe your family doctor or local urologist doesn’t recommend using vitamin E for PD, but you can now see there is a lot of science backing up this idea, and there are thousands of doctors from around the world who use it successfully. You are now aware of some of the reasons it is used as a first-line of treatment against Peyronie's disease. If you were going to use only one therapy to improve the health of your tissue and increase your chance of repairing some of the damage of PD, vitamin E should be considered as that one thing.

Using vitamin E – and therefore vitamin C – is the perhaps the most commonly recommended conservative method to assist the healing of the PD scar in traditional medical practice, as well as alternative medical practice.

I hope this information helps you understand the role of vitamin E in Peyronie's disease treatment.  TRH

How should I wash after Peyronie’s surgery?

after surgery for peyronies desease how often should you wash the penus and the best way of washing after peyronies surgery and what with?



You really should talk to the doctor who will do your Peyronie’s surgery for the specific answers to this questions.  Your surgeon will help you with this information.  

Is there a reason you believe you need to have Peyronie’s surgery?   Have you tried to help yourself so that you might not need to have penis surgery?    TRH


Which PDI treatment plan would be beneficial to my Peyronie’s disease?

I had been having problems with pain upon erection and lumps along the shaft of my penis for several months and then I started having a lot more pain.

I went to a urologist who initially told me he couldn't find anything abnormal but during a subsequent follow-up visit he told me that I have Peyronies Disease and that the lumps were plaque formation and there wasn't much I could do about it. He advised oral Vitamin E (which I take religiously) and waiting to see if it got better without injections or Peyronie's surgery.

I had never heard of this disease so I have been researching it. I do not have any obvious outward sign like scars or any curvature but I can feel the plaque deposits and have very painful erections.  Sometimes there is pain even without erections. I don't remember having any specific injury or trauma to my penis during sex but sex definitely makes the pain worse. I am really worried that although there is no curvature now, there will be if I follow the doctor's "wait and see" plan.

I already feel a "pulling upward" sensation with erections. I would like to know which of your treatment plans would likely be most beneficial to me. The biggest problem is the pain and the lumps that seem to produce this "tugging or pulling" feeling. My first thought is to jump in with both feet into the most aggressive treatment you have but maybe that is not the correct thing to do. I would really appreciate any guidance you can give me.


Thank you for your question.

You must stop doing anything that causes your Peyronie's disease to be more painful.  Pain indicates that you are again stressing the deep plaque or scar tissue of your Peyronies, and this is harmful and will delay your recovery.  This does not specifically mean stopping sexual intercourse; it only implies you must determine what you  are doing during intercourse, or how you engage in intercourse, that causes physical stress upon the penile tissue and change that aspect of your technique.   This is a huge, diverse and important subject, and for this reason I suggest you should consult a book I wrote, "Peyronie's Disease and Sex."    

Taking vitamin E by itself, or taking the wrong kind of vitamin E, no matter how religiously you take it will not help your PD.  You must use the right type of vitamin E, take it at the right time and in combination with other important therapies for it to help your problem.  Please refer to the section in the PDI website about vitamin E that covers this important subject. 

Penile distortion can occur immediately in Peyronie's disease, but it can also take months or years to develop.  Further,  I have communicated with many men whose PD distortion suddenly worsened after being static for a few years.  For this reason you must not assume your problem will always look the way it looks at this time; they usually worsen over time.    

No one can tell you ahead of time which PD plan will work best for you.   Please read "Do you simply recommend the same treatment products to all Peyronies cases?"   You will then understand that all treatment must be unique and driven by specific response of your Peyronie's plaque or scar.  Lastly, it would appear that you think that the Peyronie's scar is located on surface of the shaft; it is not.     The Peyronies plaque and scar are terms for the same fibrous material that is found deep within the penis below the skin surface; in the world of PD the scar and plaque mean the same thing.  The scar or plaque are not visible from the exterior since they are internal.

 Let me know if I can help you in any way with eliminating your PD scar with Alternative Medicine.  TRH    

Do you simply recommend the same treatment products for all Peyronies cases?

My husband, age 56, has been diagnosed by a urologist with Peyronie's disease. He has had it now for a total of about 6 months.

We live in the Chicago area.   Is there any reason for him to come see you to determine what products he should take or do you simply recommend the same products to all.



I think you have either not spent enough time reading the PDI website, or you misunderstand what you have read.

I do not recommend specific Peyronie's disease treatment to anyone, and never have.   I do not treat anyone; I do not have a doctor/patient relationship with any of the men I work with from the PDI site.  Men on the PDI website treat and manage their own PD problems, and are encouraged to directly discuss their self-directed PD treatment with their local treating doctor.   I daily suggest to a few dozen men that they should use the most diverse and broad Peyronie's treatment plan they can faithfully and aggressively follow for a few months.  This happens to be different for each man because their decisions are all different, as well as their eventual dedication and determination are also different.  As each man makes unique decisions for himself, so are their Peyronie's treatment plans completely unique.    

I do recommend that to be most effective, treatment for Peyronie's disease must be unique and specific to the man who has the condition.  In this way, I have never worked with one man who has used a Peyronie's treatment plan that was designed or used like any other man – and I have worked with well over a 1,000 men by now; all treatment is different.

 We currently have four sample PD treatment plans on the PDI website, each one nicely balanced and used by many hundreds of men.  In the description that accompanies each plan you will find that we advise each man can freely add to or subtract from these sample plans or to use them as they are.   Each man must decide for himself how he will best go about his self-directed care. 

Men do not come to me to determine what products they should take.  Men make a basic decision for which plan to start their care based usually on economics and what information they have read about the various therapies.  Regardless of how care starts, care continues and moves in the direction as dictated by how each man's scar changes or does not change in response to his treatment plan.  this change that he monitors concerns the size, shape, density and surface features of his Peyronie's plaque or scar.  In this way each individual man works directly with the response of his body to the Peyronies treatment he has started with, and in this way he not I determines independently what treatment works best for him.  I do not make any treatment decisions.   When someone asks me a question about treatment I offer in response several ideas and information based on my experience and knowledge.  But it is entirely up to each man to observe his scar response to treatment, and based on this direct information to decide how he wishes to proceed with care.  In this way each man eventually follows his own totally unique plan of care.

I recommend that a man uses the treatment products that are found on the PDI website because I have over 10 years experience working with them and I have confidence in them.   Other products you might use could be of questionable value and ability to help your husband recover.   I cannot offer ideas or information about therapy products that are unknown to me. 

Once a man has a diagnosis of Peyronie's disease there is no need for me to meet him in person.   With this form of Alternative Medicine treatment there is no need to meet face to face to discuss details or answer questions about PD treatment.  All of that can be easier and more efficiently done over the phone.   I would be pleased to speak with your husband and answer his questions about the PDI method of increasing the ability of the body to heal and repair Peyronie's disease.   TRH

Is the Peyronie’s Disease Institute for me?

Dear Dr. Herazy,

I am 65 years old and have had Peyronie's disease for about 6mos. It started out gradually when I noticed some difficulty during sex and a small pea-sized nodule on the top of penis.  It has gradually worsened where sex is impossible and erections during the night are terribly bent and painful.  I have been to a uro doc 3x and have tried various rx with little or no success.

I am an active athlete that participates in 3-4 marathons a year and train almost everyday.   The Peyronies disease problem does not interfere with these activities.

Is PDI for me?



I find that many men who appear to be in the peak of health and physical condition, like you,  still develop Peyronie's disease.   I suppose being in top physical condition does not prevent injury from happening.  Just like athletes still strain and sprain ankles and knees, they also injure the delicate tissue of the penis called the tunica albuginea that leads to PD.   Accidents happen to everyone. 

It is your decision to attempt to assist and boost your Peyronies recovery using the Alternative Medicine methods found on the Peyronie's Disease Institute website. You sound like a good candidate for our concepts, but you should only do it if you are prepared to be faithful and follow the concepts well.  Half-hearted efforts usually result in little change.  If you take that same mindset that enables you run a few marathons annually in your 7th decade, then you should do well.    TRH

Will reduction of masturbation help Peyronie’s disease?

Hello Dr. Herazy,

I am 32 and very recently developed Peyronie's disease.  I noticed the pain in early November. The pain then resolved itself by late December, around the same time two plaques appeared and a curvature of 5-10 degrees. At the time I developed it, I was under more stress than I can remember experiencing. I'm seeing a urologist next week. So that is my status but I was wondering if I currently masturbate daily do you think that reducing my masturbation by 50-75% would help. Also, in situations such as mine (young, early development, changed lifestyle (much stress now – except for the Peyronies concern)) and with the proper treatment plan the chances of recovery are high? Very very much appreciated….  J

Greetings J,

I have to smile.  Here you think that masturbation might be aggravating your Peyronie's disease, yet your solution is not to stop masturbating but only to reduce it by 50-75%.   I hope women appreciate this kind of thinking we men have when it comes to sex.

Masturbation, per se, did not cause and cannot aggravate your Peyronie's disease.   But it could have been the injury and repeated tissue strain that you sustained during masturbation that could have caused or aggravated your Peyronie's disease.   Do you get the point?   Gentle and easy masturbation that does not injure the tunica albuginea of the penis will not cause Peyronie's disease.   But the aggressive and sometimes violent masturbation practices and techniques that some men use can injure this deep tissue, causing or aggravating Peyronies disease.  It all depends on how you do it. 

The cause of Peyronie's disease is complex and not fully understood.   In my opinion your best chance for recovery is found in doing all those things that enable the body to heal as it does in 50% of men who develop PD.  This is what you will find explained in great detail on the PDI website. 

The earlier treatment starts and the more correctly, faithfully and aggressively the treatment is employed, will tend to favor tissue response and eventual recovery.  TRH