Could it be a form of Peyronie’s?

I’m 50 years old. I have no curvature of the penis, but have noticed my penis become progressively less sensitive since age 45 or so. I can maintain an erection for an hour or more, but reaching the point of ejaculation has become difficult and sometimes doesn’t happen, and is not as pleasurable as it used to be when it does.. What do you think could be the cause? Could it be a form of Peyronie’s?  What kind of medical care or treatment should I pursue?


What you describe is not consistent with Peyronie’s disease.  I suggest you go to a urologist for a complete evaluation to determine the cause and treatment of your non-PD problem.   TRH

Location of Peyronies scar in relation to prepuce, and circumcision

Dr. Herazy,
I have received my first shipment of treatment supplies and am beginning my treatment, thank you. My wife had an observation about my scar that prompted us to ask you this question. I was circumcised as a baby (it was common practice in the 40’s) and have always thought they did a lousy job of it. I have always had an excess of skin on one side if my penis, and thought it looked gross. It just so happens that my Peyronies scar is in the same area. Also my herpes out breaks would take place in this same area. The question is: have all men with PD been circumcised, and could this be a possible cause of this terrible disease?
Thank you for your insight on this question.

Greetings Lou, 

There is no statistical differentiation or predetermining factor for location of the Peyronie’s disease scar in regard to circumcision.   Men with an intact prepuce or foreskin  (uncircumcised) are just as likely to develop PD as those who have the prepuce removed (circumcised).  

Actually, on a purely theoretical and philosophical level, I would suppose that men who are uncircumcised (with a foreskin) have a slight advantage to not develop Peyronie’s disease.  I conjecture that an uncircumcised man is slightly less likely to develop PD because he has a certain level of protection against injury working for him during intercourse that his circumcised counterpart does not have.  The presence of the foreskin acts during intercourse to prevent evaporation and “leakage” of normal sexual lubricating fluids that are produced by both the man and woman.  In this way the uncircumcised man is more likely on a theoretically level to not have a “sex accident” in which the penis is suddenly bent when it rubs or presses against an area where the vagina is dry.   In actual practice I have no idea if this would actually show up as a statistically significant factor, but who knows? 

Can Avodart increase or aggravate Peyronies disease symptoms?

Can the drug Avodart increase or aggravate Peyronies symptoms?   Currently taking this medication for an enlarged prostate.


There is growing concern about Avodart use leading to or aggravating Peyronie's disease.   Currently some statistics and experts say yes, and others say no.  

The drug most commonly reported to cause Peyronie's disease as a side effect is Viagra, and the next common is Levitra. Both of these are PDE5 inhibitors used to treat sexual dysfunction.   A short distance down this list, about the 7th most common drug reported to the FDA to cause Peyronie's disease symptoms is Avodart. 

From common experience I think we have all seen the medical profession refuse to acknowledge that a drug is causing too many bad side effects, until public pressure from growing evidence becomes overwhelming and the drug is reluctantly removed from the marketplace.  The drug goes one day from being great-fine-perfect-no problem-don't get excited, and the next day it is gone because someone finally does the right thing.  

I do not have a straight answer to your question.  I do not know if Avodart causes or aggravates Peyronies symptoms.  However, when you see dark clouds on the horizon and you hear distant thunder, you should begin to question the expert weather forecast for bright skies and sunshine.   

You should talk to your prescribing doctor about your concern.  Make no changes to your prostate treatment without his/her knowledge.  TRH       

Is this an early stage of Peyronie’s disease?


My story is a bit long but I'd be very grateful to have your insight on the matter since I'm not sure about what the generalist told me and it's very hard to see an urologist where I live.

First of all, I'm 24 years old.  About three weeks ago, I noticed a blue bruise on the underside of my penis head. I do not know how it appeared but it wasn't painful at the beginning and it would come and go so I wasn't too worried then.

About a week after, the bruise started hurting after I pressed it to see if it was sensible. After that day it would hurt all the time even when I'm not touching it (even when flaccid). The pain is most of the time dull (rarely sharp) and it's coming from the inside of the penis, not the skin. At that point I figured I had a hematoma inside the penis glans.

However, two weeks later, this hematoma has worsened: the pain is now on the whole underside of my penis and not just the head. Moreover, I'm having trouble getting and maintaining an erection. One night, my penis was bent downward during a semi erection but the next day I would have a normal straight erection (and semi-erection).

I went to see my family doctor about all that and he said it may all (the temporary bent, the pain and the erectile dysfunction) be caused by the hematoma being drained downward.

I'm a bit skeptical about this explanation because I've had a lot of bruises in my life and none of them ever hurt for that long and the pain surely never spread.

I would like to know if this may be an early stage of Peyronie's disease?
– if so, will I find in your book information on how to increase my chances of recovery by acting in the early stage of the disease?
– if so, is the prognosis good for me to regain a functional penis ? (i.e. no erectile dysfunction like I'm experiencing now)

Thanks a lot for all you're doing.


You have written to ask these questions three weeks after your bruised condition (hematoma) first appeared.  This is very early to predict if your problem will develop into Peyronie's disease.   Was it your medical doctor who used the term hematoma or is that something that you decided on your own?

I am most concerned that you did not mention any specific accident or injury that would account for the bruise you have.   If a bruise appeared without a specific injury to cause it, this could indicate the possibility of a problem larger than PD.  I suggest that if the hematoma and pain does not promptly resolve from this point forward that you go back to the same medical doctor for further evaluation.

Given the disadvantage of not knowing much about your problem other than the sketchy details you present here, I can only speculate it is a possibility that your erectile dysfunction is only temporary and the result of the local problem that caused your pain and bruise to appear.

You ask too much to want a prognosis for a problem I have not seen and is so acute at this stage.   The Peyronie's Disease Handbook would provide useful information for you.   TRH

Should I be concerned about storing my DMSO?

Hi Ted,

I just ordered the DMSO. I've been concerned about storing this product in its plastic container, since it's a solvent and might pick up some of the plastic. I transferred my last batch to a glass jar. Do you think there's any basis for concern?


Greetings Bob,

The very special type of plastic used for the last 40 years by Jacob Labs as the primary container to store and deliver their various DMSO products is a laboratory grade of polyethylene; this is not your garden variety plastic.   As you correctly point out, DMSO will leach and transport many polymers and chemical elements if it is kept in the wrong kind of plastic container.  This is a subject I covered with the Jacob Lab people over 10 years ago when we first started to work together to develop a Peyronies treatment protocol.   Dr. Stanley Jacobs is a medical doctor, as well as a teaching and research professor at Washington State University, and he gave me his complete assurance that this more costly container is completely safe to transport and store DMSO.

Personally, I would be more worried about the DMSO picking up the residue of what used to be in your glass jar (mayonnaise, spices, even the soap you washed the jar with, etc.) and getting into your tissue, than anything from the original polyethylene container the DMSO comes in.


Should I get my hopes up about Xiaflex for Peyronies and Dupuytrens?

I've been reading that Xiaflex (used for Dupuytren's contracture) was tested for Peyronie's disease with pretty successful results and could be on the market as early as this year.  Should i get my hopes up?  Is this worth being excited about?


I am hearing more and more about nasty side effects and bad reactions from Xiaflex injections for Dupuytren contracture.  I think this is – or should be – the reason that Xiaflex has not been given fast approval for Peyronie's treatment.  I hate to think of what might happen if Xiaflex begins dissolving normal soft tissue structures in the penis as it sometimes does in the hand. 

From the tone of your email I get the sense that you are genuinely hopeful about Xiaflex might do for you, because you feel so helpless against Peyronie's disease.  Most men feel this way. You can get your hopes up, and you can get excited about it, if you wish.  Many people are sitting around waiting for a medical miracle cure while their lives slip away with a curved penis or useless hands.  They have the attitude that if there is no drug to save them, there is nothing to help them because the body cannot do anything against Peyronies disease or Dupuytren contracture.  Personally, I do not accept that line of thought.  I have seen too many people injured by drugs, like Xiaflex, and helped by Alternative Medicine. 

I believe a far more rational and safe approach to treating these two problems, and many others, is to first attempt more conservative treatment using a wide variety of simultaneous Alternative Medicine treatment methods.   Only after exhausting all possible conservative options would I remotely consider taking the calculated risk of a drug like Xiaflex.   The tone of your question suggests to me that you are not aware of, or even considering, the possible harm that can be done with a drug like Xiaflex.  

Many new drugs come on the market each year because of glowing reports and spectacular enthusiasm for the wonderful research results.  The new drug is highly advertised and heavily used for a while.  Then slowly and quietly new information comes out that bad things are happening to those who take this new wonder drug.  Even more quietly the drug is removed from the market a year or two later.  How many times have you heard that same story played out over and over?  High hopes based on questionable research, people hurt, drug withdrawal, many lawsuits. 

Why do we see so many TV commercials from lawyers who are trying to sue the pants off these drug makers?  The legal profession has created this large industry for themselves because there are so many bad drugs on the market and so many people who are injured, that lawyers can profit from this misfortune.  What should that tell you?  The lawyers are not making this stuff up.  They are just taking advantage of the huge opportunity they are given by bad drugs and injured people. 

Fact:  The U.S. is the heaviest user of drugs and surgery.  Fact: The U.S. is ranked about the 16th healthiest nation in the world, and we die at an earlier age, behind 15 other countries that take fewer drugs and use less surgery than we do.  If the use of drugs and surgery leads to health and long life, we should live the longest and be the healthiest country and we are not.  What does that tell you?

Sure, there are good drugs and not all drugs are bad.  But you must be extremely careful how you go about using them.  Xiaflex might help you, I cannot say one way or the other.  In my opinion, if you are going to use Xiaflex it should be the last thing you do, not the first thing.  You should certainly talk to your doctor about your decision and educate yourself to the best level you can.How you approach the treatment of your problem is your decision.  TRH 

How is your gentle manual penis stretching method used for Peyronie’s treatment?

If I am successful in dissolving or removing my plaque, does the penis straighten out on its own?. Do you recommend gentle traction at this point to assist with the straightening since the plaque would be gone?


Great question.  Thank you.

The only reason your penis is now curved since you developed the  bent penis of Peyronies disease is because there is an internal mass of dense fibrous "scar like" tissue, or Peyronie's plaque,  within the tunica albuginea of the shaft.  This plaque interferes  with the normal filling and expansion of the shaft during an erection.  If you did not have the plaque, you would not have the curved penis.   If your Peyronie's plaque is eliminated by your therapeutic efforts there will be no reason for your penis to be curved.  

The gentle traction technique that was developed during a one year research project through PDI was never intended to be a solo therapy. It was not tested as a solo therapy, only as an adjunct to existing therapy that was not advancing very well.  It made a great difference to those cases who were not responding well.   This gentle stretching protocol is not done after the plaque is removed; it is done while there is still plaque present in the shaft.  The intent of the gentle stretching is to stimulate the degradation or undermining of the Peyronie's plaque so that it is reabsorbed and removed more rapidly better while under the influence of all the other Alternative Medicine therapy you should  also be using.   

You really need to read more about the technique to understand it better.  Go to  PEYRONIE’S  DISEASE  INSTITUTE – MANUAL PENIS STRETCHING METHOD CD©      Be sure to watch the video that demonstrates the actual method.    TRH

How should I use moist heat to treat Peyronie’s disease?

What do you recommend to use for "moist heat" and to what temperature and for what duration & frequency?

Thank you.


Moist heat is often overlooked as a part of Peyronie's disease treatment because it is common and not flashy or scientific.  It quickly, easily, cheaply and very effectively draws blood to the area of your treatment. Add it to your therapy plan today. 

A moist heat pack can be made by wrapping a towel that has been soaked in hot water around an old fashioned rubber hot water bottle to keep the temperature sufficiently hot for the time it will be used.

Since many people would not have easy access to a thermometer to actually test water temperature,  I will only comment that a good temperature for water for the purpose of making a moist hot pack to use for Peyronie's treatment is somewhere in the area of 105°F, give or take a few degrees either way.   Most people just hold their hand in the flow of water and know what temperature will feel good and still be safe to use.  We always caution to use a safe water temperature that will not cause tissue burns to this delicate area of the body.  I would hope that common sense and past experience will guide everyone to know how to keep themselves from getting burned.

Duration should be at least 10 minutes to bring enough increased blood flow to the area to provide therapeutic benefit; longer if you have the time and opportunity.  I suggest that you should use such a hot pack before you do any of the external therapies: manual penis stretching, DMSO, vitamin E and copper peptide applications, or the Genesen Acutouch pointer therapy. 

It is very safe if you are careful and use common sense.  Do not fall asleep while using a heat pack, and do not use a water-proof electric heating pad because if you do fall asleep with one it can continue to "cook" you while you sleep.  TRH 

Would you advise against “hanging weights” from the penis as a way to treat Peyronies?

Sorry if you've answered this in the past but I didn't see it on here…would you advise against "hanging weights" from the penis? I'm not sure if this is can be as damaging as extenders but I'd just like to get a consensus before I spend any more money on this penis of mine.

I can see why penis stretchers/extenders might not work but with weights, it is gravity after all.

-Just around the bend

Greetings Just around the bend,

Yes, it is only gravity.  Try telling that to the fellow who has a brick fall on his head. 

Gravity is a universal force of attraction that increases with the mass or weight of an object.   The effect of hanging a grain of rice from your penis is far different from hanging a brick from that same sensitive organ. 

In regard to the idea of hanging something from the penis, this is the essential problem with this strategy of penis elongation:  How do you attach the hanging weight to the penis in order to stretch it?   Unless your penis is vastly different than those I have seen, your penis does not come with a handle or other point of easy attachment for this weight.  There is no good safe way to attach a weight in order to traction the penis.  For this reason the usual strategy is to tighten some type of clamp to hold onto the head (glans) of the penis to produce a traction force. And this is where the trouble starts.  The tightened clamp that is applied to the glans can easily cause blisters or tissue erosion, as well as problem related to decreased blood flow as a result of the prolonged pressure. 

Even if your penis does come with a handle to which you can safely and conveniently hang a weight, what good is that in relation to Peyronie's disease?  When you stretch the penis forcefully you can only stretch the elastic and normal tissue, not the dense and fibrous scar material.   The normal stretchy soft tissue of the penile shaft will stretch long before the fibrous scar, and so all traction force will be absorbed by the normal tissue.  Nothing will happen to the scar material using this strategy.

It seems that most men are naturally interested and want to believe that making their penis larger is beneficial to treat Peyronie's disease.  I have seen too many cases of Peyronie's disease start with the use of hanging weights and penis stretchers to know that this is not a good idea.  Sorry.  TRH

Not sure what to do next for Peyronie’s treatment

I have Peyronie’s disease for over 3 years.  Lately, the curvature is 45 degree and bending rapidly. It’s preventing me from concentrating and keeping a firm erection. This condition is starting to affect emotionally.  I avoid having sex.  I’m 52 years old and married for 25 years.

I had taken Potaba pills and did not work. For the past two weeks I have been taken Vitamin E. Not sure what to do next.

Looking forward to hear from you.

Your help is greatly appreciated.    Thank you.

E. Garcia


Greetings E. Garcia,

vitamin E by itself is not very effective as a Peyronie’s disease treatment, but then again there is nothing that when taken by itself will be effective.   To get truly good results with your vitamin E you must combine it with other therapy products to support and increase your body’s ability to remove the PD plaque material.

POTABA is not a well tolerated drug and it is not especially effective against Peyronies.  POTABA is a modification of PABA, a member of the B vitamin family, that is made into a drug by adding a potassium molecule onto the vitamin.   This was originally done because PABA received good research results as a Peyronies treatment, but the drug industry would prefer to sell drugs and not low-price and ow-profit vitamins.    So they created the drug POTABA that irritates the dickens out of the digestive track so much that few men can take the drug very long, and it does not work as well as PABA anyway.   For this reason we continue to suggest the use of PABA in Peyronie’s treatment plans.   

Please go to the PDI website and click on the link Start Peyronie’s treatment.    This is a good starting point to begin to put a plan of action together for your recovery.  Keep in mind that an important element of a good treatment strategy is to do a variety of Peyronies disease exercises along with using vitamins, minerals, enzymes and herbs to support your natural recovery.


Please let me know if you have any specific questions.   TRH