How to work for the best chance of recovery from Peyronie’s disease?

Dear Dr. Herazy,

Six months after undergoing a double nephrectomy in July 2009 I discovered that I had symptoms of Peyronie disease.   My kidney diagnosis was papillary renal cell carcinoma and I have been receiving hemodialysis since surgery. I purchased your PD manual in 2010 and have studied it. My self care emphasis has been mostly just tracking the scar closely. I have a 45 degree up curvature; rt side shaft base indent of 1/2 inch when hard from a plaque scarring that feels the size of a postage stamp; a left side shaft base lump the size of a large oval tablet located adjacent  to the urethra. Together these scars produce a severe hourglass just above the shaft base during erection. My Dr. also has identified plaque buildup on the top of the "T" along the whole shaft.  I tried one bottle of neprinol, taking 6 tabs twice a day and did not detect a change.

My request is that I would like to work with you on a structured therapy with the goal of healing these scars and symptoms and hope fully the PD cause. I would like to give myself the best chance for recovery.


Tim Kay


Greetings Tim,

Sorry to hear of your recent health problems.  

Fairly often I am told stories similar to yours in which Peyronie's disease starts after having serious surgery that requires catheterization, as probably happened in your case.  Injury to the penis typically occurs while the patient is unconscious and unaware of the forceful entry of the catheter into the urethra.  

Taking Neprinol by itself is seldom able to reduce the Peyronie's plaque material; a large and diverse program of care must be used to support the body to heal the plaque formation.  I suggest you consider following the largest and most aggressive therapy plan you can to get started in the right direction.  

I would be happy to work with you to answer your questions and provide options along the way.  Please let me know how I can assist you.   TRH 

How can I get on the offensive after penis fracture surgery?

Hi doctor,          

How can I get on the offensive after penis fracture surgery I had two months ago. I don't acquire any scar tissue that could result in Peyronie's disease.  Is there anything you can recommend for me so soon after surgery that might help me prevent excess scar tissue from forming?  James

Greetings James, 

I suggest you consider using a PDI small plan along with Omega T in your situation to assist your tissue to heal with minimal scarring. With this approach you will supply many of the basic nutrients to your tissue  to heal your injury in this way.  At least you will have assurance that you will reduce the degree of damage if in fact some scar develops.  TRH



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Is the reduced penis size typical of Peyronie’s disease?

Dear Dr. H.,

I have had peyrones for about 2 years.  In that  time my penis has gotten noticeably smaller, shorter, and skinnier.   At first it looked like it did (flaccid) when I was a 10 year old kid!   And when erect, it is also smaller and bent.  Is this decrease in size a typical part of my peyronies condition?

Thank you for your response and God Bless you for all your work.

Again, thank you,



Greetings Joel,

Most men who develop Peyronie's disease begin to notice some reduction in penis size between the 6th to the 12th month.  Since everyone seems to follow a slightly different timetable for these changes this is only a guess based on information from 100s of men.  Some men experience size reduction sooner and others are later. Penis size reduction is caused by widespread thickening and contraction of the tunica and other soft tissue of the shaft that no longer can expand when the penis is filled with blood during an erection.  

This variation is also true for amount of lost erection size; some men more and some men less loss.  I have also noticed that some men lose more length than girth, and others lose more girth than length.  All of this variability is common for the way Peyronie's disease is inconsistent in so many ways. 

Loss of  penis size is a very common part of the process.  It seems that most men complain of losing 1 to 1-1/2 inches of length and about that same loss girth or circumference.   I do not recall anyone saying he has lost more than 2 inches of length, although it might only be that someone who has lost this much length is reluctant to admit to it.    TRH