Connection between bladder inflammation and Peyronie’s disease?

I have interstitial cystitis that I developed about 2 1/2 years ago where I feel constant low grade pain in my penis – with tender areas of the shaft. I noticed the curvature of my penis has gotten significantly worse with time and erections now are painful and seem to pull beyond the capacity of the ligament causing an upward and left bend. Have you heard of a connection between Peyronies and IC? I am also on treatment for gut pathogens and am concerned about any of the PDI treatments which might reduce my body's immune response since I need it high to fight my gut pathogens. Given this, where is the best place to start? Can I have a phone consult?


Interstitial cystitis is a problem of unknown origin causing chronic and long term low grade inflammation of the wall of the urinary bladder.   In these cases pain is felt during intercourse and in general in other parts of the pelvis, along with pain during urination.   The bladder wall inflammation causes both urinary urgency and frequency up to several times an hour.

Of course I am at a great disadvantage in not really understanding your full history.  What I can tell you is that there is typically no direct causal relation or connection between interstitial cystitis and Peyronie's disease.  However, based on what you have mentioned in your email you make it sound like you have two independent problems going on, and it would seem that if this is true you would probably have to deal with them separately.

The natural Alternative Medicine treatment for Peyronie's disease recommended by PDI would not do anything to reduce your immune response, but would probably enhance and strengthen it.

Probably the best place to start is with a telephone discussion of your problem and to help you develop a viable treatment strategy.  Please contact me at 847-670-8800.   TRH