Could ultrasound treatment help with some of the ED that is part of Peyrnie's disease?

I think that I got some positive results from taking Neprinol. I will continue to take at least six pills/day.

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My question is for the ultrasound machine that you have. I was wondering if this could help with some of the ED possibly.

Thanks,

John

Greetings John,

Taking any therapy by itself as a solo treatment is not a very effective protocol; usually Neprinol must be combined with other therapies for maximum effectiveness.

Having some degree of erectile dysfunction (ED) with Peyronie's disease is not uncommon.  It is due to the presence of the Peyronies scar preventing full closure of the veins that trap blood to create increased hydraulic pressure needed for an erection to occur.  The answer for this kind of ED is to reduce the size of the PD scar material, or get rid of it altogether, so the veins can close again as they did before you developed Peyronies. 

Here is some additional information about this subject: Should I use Neprinol as part of my Peyronie’s disease treatment?

The ultrasound machine is proving to be a good therapy to add to a basic PDI style treatment plan, based on the reports I am getting back from men who are using it in combination with broad therapy plans. 

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What program would you suggest I try for my four year-old Peyronie's disease?

I have had Peyronie's Disease for probably 4 years or so (not initially diagnosed) and the initial bend and associated pain is no longer apparent. I have several plaques on the shaft and these cause somewhat of an hourglass effect and an associated constriction.

I no doubt have suffered from depression during this period partly due to feelings of guilt and helplessness. I have taken l-carnatine and more recently Neprinol. I have found that if nothing else doses of vitamin E have also been good for my skin health.

More recently I have been diagnosed with Ehlers-Danlos syndrome. I am in quite good health and have not experienced any loss of sexual function. In taking the Neprinol – this is probably of no association – I now wake with an erection.

I recognize that I should have acted earlier but as it took several attempts to find a doctor that could actually offer help I had already somewhat resigned myself to my fate. As described there has been substantial improvement from the original condition and I am looking to continue my recovery. What program would you suggest that I try? I look forward to receiving your advice.

Greetings,

As I suggest to all men who contact me with the same basic question about what program to get started with, I think you should visit the page  Suggestions to help you decide how to start Peyronie's treatment.  This is a good starting point for anyone who wishes to increase his ability to naturally heal and eliminate the offending Peyronie's scar tissue.  The basic idea is to support and encourage the strongest healing response possible by using the largest and most aggressive plan you can use for at least 2-3 months.

It is encouraging to think that you saw some degree of improvement by just using acetyl-L-carnitine and Neprinol.  This is not a good plan design, so if you decide to use what we offer as a viable treatment plan I would guess your results would be considerably better than what you did on your own. 

Fifty percent of men who initially develop Peyronies will cure or eliminate it without any outside help.  You saw what your body could do when you helped it a little in a lop-sided way.  The PDI therapy idea is simply to encourage that natural healing ability by supplying at the same time and in an elevated dosage all possible nutritional elements to help that healing process along.  

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If I can help you in any way, please let me know. TRH

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Questions about taking Neprinol in a Peyronie's treatment plan

Hello Dr Herazy,

I have a question regarding the intake of Neprinol and the absorption of proteolytic enzymes. I understand that they need to be taken away from meals. My understanding is that on an empty stomach they act/are absorbed in one way, and with food they act in another way. On your site somewhere you say they they should be taken 90 minutes before or 90 minutes after eating. 90 minutes before eating sounds extreme. Surely they are out of the stomach and on the way to the intestines in a lot less time than that. And by the same reasoning, taking them 90 minutes after eating … wouldn't there still be food in my stomach at that time? 90 minutes before suggests REALLY away from food; but 90 minutes after suggests that mixing it with food then is OK. Can you clarify this a little further. I just want to be sure what I take can be as efficacious as possible. My practice has been to take it 15 to 30 minutes before eating. (At which time I also take other herbs (for other non-PD concerns) that also need to be taken on an empty stomach.  Thanks.

Walter

Greetings Walter,

What you are asking about is called “gut transit time,” or the amount of time it takes for food to pas through the digestive tract, as well as absorption rates for different molecules that pass through the stomach wall. As you can imagine, this is a variable factor from one person to the next. The 90 minute stipulation is a good average for most men following a Peyronie's treatment plan,  but it might far shorter or far longer than it should be for some people; yet, it is a good average.

If you feel that you need to increase or decrease these times for taking Neprinol based on your personal digestion physiology, by all means please do so. Having said that, I would caution you that you should err on the side of assuming there is food in your stomach longer than what you think. Please give yourself a bit more additional time when taking the enzymes before a meal, and give yourself a bit more additional time before you eat after taking the enzymes. The world will not come to an end if you take your enzymes to close to the time you are going to eat, or you eat too soon after taking enzymes, but your therapy will be diminished and Peyronie’s treatment is too important to make this kind of error.

You write that you take your systemic enzymes 15-30 minutes before a meal. That might be perfect for you, but it might not be enough time for the next person. Further, that might not be enough time for your stomach to get the enzymes into your blood stream and into the fibrous tissues. How would you know?

You write that taking Neprinol 90 minutes before a meal sounds extreme to you, but I must wonder what you base that on. All I propose is that you give your gut ample time to get all the systemic enzymes through the gut wall, into the blood stream, and disbursed to start working on the excess foreign protein that is in the Peyronie’s scar. Maybe this can take place in 17 minutes, or 59 minutes, or 90 minutes, no one knows for sure because these particular digestive enzymes have never been studied for absorption times or delivery times. So why not make sure you allow enough time to allow it to happen so you get the best results from each and every dose you take?

If all you are doing is using that “full stomach” sensation to judge if food is still in your stomach you might be incorrect. Many people have food still being digested for hours after a meal – they might be exceptions, but it does happen. Further, gut transit time – the time food stays in the stomach – changes in the same person from one meal to the next depending what kinds of fats, carbohydrates and proteins are in each meal, and changes based on your emotional state, how well or poorly you chewed your food, how physically active or rested you might be at that time, how warm/cold you are, and other factors.

Lastly, let me guess that your question is not based on the usual situation in which you can control your food and enzymes schedule perfectly. I will guess you are asking this question really based on those days when your schedule for eating, working, and taking a handful of different therapy items is totally out of your control. We all have too many of those days when we forget to take Neprinol 90 minutes before we eat, or we absolutely will not be able to take the Neprinol 90 minutes after we eat. What do we do then? When we cannot allow ample time to take systemic enzymes on a good schedule because of forgetting or something we cannot control, what should we do? Do the best you can. Then promise yourself that the next dose will be taken at a better time to allow for better absorption and delivery. That is all you can do.

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Give your gut ample time to empty food, and to absorb Neprinol, so as to maximize the ability of Neprinol and other proteolytic enzymes to the target Peyronie’s disease fibrous scar material.

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Could you recommend the best way to buy a range of Peyronie’s therapy products?

Hi Dr Herazy,

I have had Peyronies for 2 or 3 years now and visited a GP who said if does not interfere then leave it but things have changed lately

I have an upwards curvature and can have sex but the penis is not hard enough and I am not able to ejaculate easily – I have no pain

I am in Australia and want to order products.  Because of freight I should get a sufficient supply- I notice you have packages but they do not contain Neprinol.  I read about and would like to order Neprinol – could you recommend the best way to buy a range of products

Also can you give me your thoughts on the use of penis extenders to correct the curvature

Thanks

Paul Craig

 

Greetings Paul, 

Sorry to hear of your problem.

You were given the stock medical information:  “If you have Peyronie’s disease and have a curved penis that does not interfere with sex, leave it alone until it is bad enough to bother you and we can talk about penis surgery.”  In my opinion, this is bad advice because you have lost time and opportunity to do something to help yourself recover from PD.  Your Peyronies problem has slowly worsened during that time so you will now have more work to do in order to recover. 

The softness of your erection is due to the Peyronie’s scar preventing the valves in the penile veins from closing completely.   When this happens the veins cannot trap blood in the penis to engorge it with blood, and insufficient hydraulic pressure is created to develop the usual hard erection to which you have been accustomed.   The problem is not ED (please do not take ED drugs like Cialis and Viagra because they can make your Peyronie’s disease worse), but the problem is the presence of the PD scar.  The scar is acting like a foot being put in the door way and preventing the door from closing.  You need to reduce the size and density of the scar so your penile veins will be able to close once again.  

Neprinol is a wonderful product.   It contains serrapeptase, nattokinase, bromelain, co-enzyme Q and papain in a good ratio at a high concentration. By far, it is most popular systemic enzyme product we offer as part of any Peyronie’s disease treatment plan.

Most, if not all, of the information you will need to use Neprinol to reduce or eliminate the fibrous Peyronie’s plaque can be found at the Peyronie’s Disease Institute website. Please visit our website for additional information not only about Neprinol but diverse and synergistic group of valuable Peyronie’s therapies.

There are two reasons Neprinol has not been included in any of the three standard PDI therapy plans we offer.  It was omitted from these entry level plans due to the rather the practical consideration of not starting treatment with a potent enzyme product like Neprinol. Some men cannot handle the dumping of tissue toxins that such a concentrated enzyme product sometimes produces.   Also, there is the economic consideration.   Neprinol comes in such a large bottle (300 capsules, compared to 100 capsules of Nattokinase or Fibrozym), and the ingredients in Neprinol has 6-8 times more concentrated “functional units” of enzymes.  Therefore, it costs more initially but this is actually a better deal because of better results and the fact you would be taking fewer of them.   If Neprinol was included in any of the standard Peyronie’s disease treatment plans the higher price might discourage some men from starting treatment.  For these reasons the smaller and less concentrated Nattokinase and Fibrozym are included in the small, medium and large Peyronie’s treatment plans, to allow a man to acclimate his body to the changes these enzymes can create. 

The best way to get a diverse range of  products at the best price is to purchase any of plans you find on the PDI site.  The most popular plan is the  medium Peyronie’s treatment plan, but the one that gets best results is the large plan.   You can modify any of the plans you see, either making them smaller or larger as you choose to do so, based on your current thinking.  In your case you can also follow the basic format of the small, medium or large plan, but remove the Nattokinase and Fibrozym and replace both of them with a single bottle of Neprinol.   Your choice.

Penis extenders can hurt you, as they have injured many men to whom I have spoken.  Please read Penis Extender Claims and Peyronie’s Disease or Penis Stretchers:  Big Problem as Peyronie’s Treatment.    TRH

Is it safe to take Neprinol with medication?

hello my name is kathy ! i am 44 yrs old and had two heart attacks and open heart surgery four years a go and i take fish oil and 325asprin and metoprolol 25 mg but i take half of a pill.is it safe to take neprinol afd with my medications . thank you kathy


Greetings Kathy,

Please discuss this question with the physician who prescribed your various medications.  In my opinion there would be value in your taking Neprinol, but you must monitor your blood clotting rate while you balance your intake with the drugs.  However, you need to have this issue completely regulated by your treating doctor before you make any changes or additions to what you are now taking.   Good luck to you.  TRH

Best Peyronie’s disease treatment, Neprinol 300 or Neprinol AFD?

Neprinol reduces inflammation and tissue damage

Neprinol is a completely vegetarian blend of several different enzymes that have tested to have over six time’s stronger activity to break down fibrin than the leading animal based enzyme blend product.  The enzymes in Neprinol have been shown to be clinically effective in supporting C-reactive protein (CRP) levels when taken as directed.  In this way Neprinol promotes normal levels of anti-inflammatory markers in the blood stream that are part of the physiologic response of the body while  dealing with acute (sprain, strain, overwork) and chronic (arthritis, most soft tissue disease, stroke, blood vessel disease) injury.  As a result Neprinol enzymes will assist the body in its effort to eliminate from the blood stream damaged red and white blood cells, fibrin, any protein material that is part of the inflammation process, as well as other cellular debris and foreign protein that can accumulate in the blood.

Neprinol AFD important in treatment of Peyronie’s disease because it affects fibrin

Fibrin deposition in Peyronie’s disease plaque

Immediately after injury occurs in the body, a protein called fibrin is deposited at the site of injury to act as a meshwork to trap and collect important blood cells and helpful components that create a clot that stops bleeding and promotes healing and repair of the recent injury.  This is normal.  After a period of time this mass of fibrin with it cellular collection changes so that the fibrin is removed and another protein called collagen fills in the spaces and changes the area of repair so that it resembles a fresh scar.  This is normal.  However, in Peyronie’s disease two abnormal things occur, for reasons that are not understood:  the fibrin does not leave the clot, and an excessive amount of collagen forms in the young scar so that it takes on a different name, a Peyronie’s plaque.  The way this fibrin and collagen collect and remain at the site of injury is consistent with repetitive injury to the small blood vessels of the penis.

The benefit of Neprinol AFD to Peyronies treatment is that it can break down and assist the removal of the fibrin that remains in the Peyronie’s plaque or scar.

Neprinol 300 most popular systemic enzyme sold by PDI

The ability to break down fibrin with enzymes, and to do it as economically as possible because it is a larger size bottle, is the reason some people call it Neprinol 300.  The high potency of two key enzyme ingredients, nattokinase and serrapeptase, address the concern about aggressively placing a systemic enzyme product as the foundation of treatment. Start by taking only four Neprinol 300 capsules daily, then slowly increase dosage while monitoring the size, shape, density and surface features of each Peyronie’s scar.  This is a great way to use this Alternative Medicine therapy for treatment of Peyronie’s disease. Neprinol 300 is recommended for both clinical use and therapeutic applications.

No difference between Neprinol 300 and Neprinol AFD

Whether you choose to call it Neprinol 300 or Neprinol AFD, these two terms are simply different names for the same potent enzyme therapy supplement that most people simply call Neprinol.

Neprinol continues to be by far the commonly used Peyronie’s disease therapy product.  Many times I have seen men who are following a particular plan that does not include Neprinol, and they experience slow or totally stalled results.  After adding Neprinol to that same plan it is common to learn that their recovery greatly improved from that point forward.

The name Neprinol 300 refers to the fact that Neprinol is bottled in either a 300 or 90 count bottle, for your benefit.  With the larger Neprinol 300 size bottle it is possible to take advantage of the reduced price of a greater supply and to purchase it fewer times; this is especially helpful for those who use Neprinol for chronic health problems that require prolonged treatment.  With the smaller Neprinol 90 count bottle it is possible to keep a smaller amount on hand for relief from occasional and mild overwork injuries or to simply get acquainted with the Neprinol product by taking a small amount of it.  By far, Neprinol 300 is a much more popular product.

The name Neprinol AFD refers to the primary purpose of Neprinol, as an Advanced Fibrin Defense therapy product.  Neprinol AFD is a name that tells the story that reduction and elimination of fibrin from the blood stream and tissue is what this product is all about.

Neprinol is safe

In over 10 years of use through the Peyronie’s Disease Institute there has been no report of any serious complication or adverse side effect associated with taking any systemic enzyme product like Neprinol, when it is taken in the way that we suggest.  Worldwide experience during this time has revealed, as well as clinical studies have demonstrated, that taking extremely large doses of this product does not result in a toxicity reaction.  Anyone taking a prescription for blood-thinning medication should consult with his treating physician prior to taking Neprinol.

Neprinol for Peyronie’s treatment

As good as Neprinol is when used to reduce Peyronie’s plaque material, it is almost always necessary to use several other in addition to the Neprinol to support and sustain the desired tissue changes.  Neprinol is best taken as part of an already good therapy plan, often used as a substitute for low dose nattokinase and serrapeptase supplements, although some men use all three products with very good results.

Neprinol AFD contains primarily serrapeptase, nattokinase, bromelain, and co-enzyme Q, plus a few other lesser ingredients. Other products also contain serrapeptase and nattokinase, individually, but few put these two in combination and none in the concentration of Neprinol AFD.  It is a more potent form of nattokinase and serrapeptase than if you would buy each in individual bottles, and the Neprinol 300 bottle itself is three times larger than most others that contain 100, to say nothing of smaller bottles with 60 or even 30 capsules.

However, in regard the idea of successful PD treatment is to not focus on any one particular therapy, even if it is a great one like Neprinol because the goal is to attempt to create a synergistic effect with several therapies taken at once for maximum therapeutic effect.  For this reason the Peyronie’s Disease Institute has always maintained that even if someone believes Neprinol (or any other) is a key PD treatment it should not be taken alone but combined for greatest therapeutic benefit.

No one knows how any one will respond to any or all of the 13 Alternative Medicine therapies found on the PDI website.  Some men report some positive results with just one therapy, but more men report better results when they take multiple therapies.  That is what the whole therapy concept of synergy is all about:  the more you do, the larger your plan, the greater the likelihood of promoting a favorable metabolic change to support and encourage scar reduction.  The PDI idea is not to “treat the scar” as a medical doctor would do, but to “treat the man who has the scar” so that his body can heal what is wrong with it.  This is a major concept shift for most medically indoctrinated people.  For this reason, as good a single therapy as Neprinol is, it is not recommended that anyone who is interested in earning good results in treatment of his PD scar should use just Neprinol – or just any one product – but several to create synergy.

Peyronies disease is a tough and terrible thing to happen to a man.  It takes dedication and persistence to overcome it.  Call it Neprinol 300 or Neprinol AFD, but definitely use it in a well diversified plan to break down the fibrin network of your Peyronie’s plaque material.  Success over this problem is never an easy victory, but always worthwhile.

 

What are your thoughts on Pentoxyfilline for Peyronie’s disease treatment?

Hello Doctor,

I’ve been dealing with this crazy Peyronie’s condition for about 18 months. In that time, I’ve visited 4 different urologists. The first was when I first experienced mild pain in the left tip of my penis. The doctor diagnosed it as prostatitis and send me on my way with some antibiotics. A second urologist several months later diagnosed me with superficial vein thrombosis. Finally, several months after that, I was diagnosed by a third urologist with peyronie’s which seemed to appear as long bands of inflammation from the base of the penis to the tip on both sides. I was told surgery was the only option, and was sent on my way.

Not satisfied with the suggested treatment plan of surgery, I decided to surf the web and do my own research. I found a site that promoted Neprinol as the only known cure. So I bought into it. I think I tried 2 full months (9 pills a day). The only result was a substantial hit on my wallet. So I went back to the web and found another site (PeyroniesForum.net) where members talk about various treatment options. The consensus on the site was that Neprinol was in fact a huge scam, and I stopped using them. Members also praised the use of Pentoxyfiline as being an outstanding product for softening scar tissue and alleviating curved penis. So I went back to a fourth urologist and asked for a prescription, but was denied. Instead, i was recommended to try the Andropenis traction device.

I’ve been on the device for 5 full weeks now, but I think I’ve decided to stop. Your website recommends against it, as well as another site. My urologist described it as working in a manner opposite of what a Nesbit procedure would be. For instance, rather than shorten the penis on the site opposite the scar tissue, traction would elongate the scar tissue to correct curvature that way instead. Made sense to me at the time. But now it sounds as if traction does not work because it’s not really stretching the scar tissue, rather only healthy tissue.

So if I stop with traction, I’ll be happy to not deal with that contraption any longer. It reminded me of having my penis in a mousetrap for 9 hours a day. Not to mention I always worried about whether people could see it jutting out through my trousers at work, and despised having to take it off every two hours to relax. That’s not always easy in the middle of a busy work day.

In any case, I came across your web site again. I’ve decided I’m going to give your “Medium” package a try, so I placed an order. I admit I’m very reluctant because you seem to be a heavy proponent of Neprinol, and I’ve heard people state emphatically that the product is a scam. I also ordered your Handbook. It’s expensive, but maybe there’s something in it that I can learn.

I do have a few questions if you wouldn’t mind responding. Today, I have two “knots’ in my penis. One that feels about the size of a dime on the right size near the base of my penis. Another is about the same size, also on the right size, but towards the tip. But my penis bends to the left when flaccid (sometimes 10-20 degrees, sometimes 45 degrees like after masturbation), and I can’t figure that out. That’s seems counter to everything I’ve heard before, that the bend is on the same side as the plaque.  So if you have any insight as to why my bend is to the left when my plaque is on the right, I’d be very interested. Regardless, that leads to my first question, how will I know where to apply the topical treatments? Would I apply to the right side where the “knots” or “bumps” are located, or should I be looking somewhere on the left side for plaque? Or should I just apply the treatment to the entire penis shaft? Maybe directions come with the kit, but any advice you can share would be greatly appreciated.

Second, can you share your thoughts on Pentoxyfilline and it’s effectiveness for Peyronie’s. Not sure if I’m spelling that correctly.

Finally, who can I find a coupon code? I noticed when I placed the order for one medium package and one book, that there was a place to enter a coupon code. I did some web surfing to find a code, but was unable. If you can share a code, or apply a n appropriate discount to my order, I’d greatly appreciate that.

Hope you’re doing well. Looking forward to your thoughts.

Mike

Greetings Mike,

Thank you for your informative letter and specific questions.  I will reply with comments and answers in the order of your email.

There is no direct known cure for Peyronie’s disease.  Neprinol is not a cure, but is is not a scam.  In my opinion, after working with many hundreds of men from around the world who are undergoing Alternative Medicine treatment of Peyronie’s disease, I know Neprinol is an excellent enzyme product.   It cannot be counted on as a solo therapy for Peyronie’s disease since none of the products found on the PDI website are by themselves able to change the PD scar or plaque material.  None of the therapies found on the PDI website are good solo therapies – they all must be used as part of a larger plan to support the natural healing process that is the only known form of cure for Peyronie’s disease.   When Neprinol is combined properly and taken aggressively the results can be dramatic.  I do not know how any of the experts on the various Peyronies forums actually used Neprinol when they took it, but many times when I communicate with men about their failure with  Neprinol I learn that they “tried it for a few weeks and it did not work,” or “I took two pills a day and it did not work,” or some similar manner of use that is doomed from the start.   In order to get results from Neprinol it must be used correctly.  If you bought your Neprinol from PDI we warned you not to use it that way; if you bought it from someone who does not know anything about PD you did not get that kind of help so you would know better.  Peyronie’s disease is a tough and tenacious problem to treat.  I am not surprised at your lack of results after using Neprinol as a solo therapy.

Here is a simple example that just occurred to me about Neprinol and PD:   Beans are a great food.  I like beans.  But by itself beans make a lousy chili – it is just beans.  For a good chili you have to add meat, garlic, onions, tomatoes, lots of different spices and a few other items.  It is only by combining the beans with all the other ingredients that you create chili.  None of the ingredients by itself is chili.  It is in using the correct technique (there are rules for bringing the ingredients together, you cannot just throw everything into a pot) when you bring all these things together to develop the magic that becomes a great bowl of chili.  Same with combining Neprinol with the other things your body needs to help it overcome and correct your curved penis and Peyronie’s disease.  

Pentoxifylline is popular with some urologists and not so much with others.  I think that those who actually prescribe pentoxifylline do so because they are tired of dealing with the other drugs that do not work and only use this one because they do not know what else to use.   Perhaps I am being overly skeptical and blunt in my assessment.   Some time back I wrote two articles that might be helpful on this subject, Pentoxifylline, Niacin and Peyronie’s Disease and Pentoxifylline and Peyronie’s Disease Treatment

Every month I hear more horror stories about the mechanical penis stretcher devices.    You did not indicate what problems you were having that you wanted not to deal with it any longer, but it usually has to do with pain as well as skin abrasions and blisters, and the fact that it does not work for the large majority of men.

The two plaque or internal scars you have located do not explain your deviation to the left.  My experience is that Peyronie’s plaque are usually multiple.  I suspect that the two you have found on the right are not the only ones that you have.  I suspect you also have one or more plaque on the left that are far more aggressive and instrumental in distorting your penis that those you have found on the right.   Let me know if you need help locating the other scars and I will assist you.   If you can not locate those scars on the left that are causing your distortion pattern I suggest that you apply the therapy at the deepest or lowest point of your concavity on the left. You could apply the DMSO, Super CP Serum and Unique-E vitamin E oil to the entire shaft if you wanted to, but it is unnecessary and wasteful; be as specific as possible.   I trust that the detailed DMSO instructions you received with your order cleared up this point for you. 

When you received your order you were given information about the use of a discount code for subsequent orders.

Let me know if  I can help you in any way.  TRH 

 

Can Neprinol be used in my Peyronie’s treatment plan if I am sensative to soy?

Hello Doctor,

I was reading about soy free Neprinol AFD on the PDI website.  The statement "soy free" caught my attention.  For some time I have been taking a soy-based energizing protein supplement.  Is there some connection between PD and soy?

About a year ago I began to mix the soy protein with a whey protein in a 1:2 ratio.

Thank you for a very informative web-site.

Sincerely,

Bill

 

Greetings Bill,

There is no statistical or clinical evidence to suggest that Peyronie's disease is related to soy intake. That information about Neprinol being soy-free is based on the need of many people to avoid soy in their diet; it is mentioned to let those know who are sensitive to soy that Neprinol can be used for their Peyronie's treatment.  TRH


Is Neprinol is a better Peyronie’s treatment option than Fibrozym and Nattokinase?

If I order Neprinol how much should I lower my present dose of Fibrozym and Nattokinase 1500 dosage to?    I am currently on 7 pills Fibrozym and 5 pills of Nattokinase 1500.  Also do I discontinue fundamental sulfur or continue while on Neprinol?   Do you believe that Neprinol is a better option than Fibrozym and Nattokinase 1500 overall?

Greetings,

Neprinol is a more concentrated form of the systemic enzymes that are found in Fibrozym (serrapeptase) and Nattokinase 1500 (nattokinase).   Neprinol has a higher enzyme activity rating than these two other products.   However, it is not always true that stronger is better or more effective Peyronies treatment.  

My suggestion is that you work with Neprinol to see how you will respond to it compared to Nattokinase and Fibrozym.   You could start taking a total of 4-5 Neprinol daily to determine if changes occur in the size, shape, density or surface features of your scar.   If you determine that there is a positive change in your scar, then you maintain that  same 4-5 Neprinol dosage until your scars disappear.   If at that dosage there are no positive changes in the scar, then you can increase your Neprinol intake until you see reduction of the scar size, shape, density or surface features.  It always comes down to what your tissue requires to make the changes you want.

Many men take all three enzyme products with Neprinol being the primary or lead therapy, but also keep a few Nattokinase 1500 and Fibrozym in their plans as secondary or minor sources of systemic enzymes.
    TRH

 

 

 

 

 

Why isn’t Neprinol included in the medium Peyronies treatment plan?

Dr.Herazy,

I have started using the medium plan.   I noticed, however, from your response to a question about Neprinol that you thought that Neprinol was more focused than Fibrozym and Nattokinase.  If this is so, why isn't Neprinol included in the medium plan?

Thank you for your response.

 

Greetings,

There always seems to be some question about Neprinol when used in Peyronie's treatment.   Here is something that I copied from the PDI website that you might have missed along the way that will explain my thinking about Neprinol in the initial plan usage:

 

"Hey, wait a minute!  I do not see NEPRINOL in any of these plans!  Why do you have Fibrozym and Nattokinase 1500 in these plans and not Neprinol?"   

"Neprinol is not included in the PDI Small, Medium or Large Plans for two reasons:

     "1.  Neprinol is more powerful than Fibrozym and Nattokinase 1500.  It contains the same enzymes as Fibrozym and Nattokinase 1500 – at perhaps 10-12 times greater bioactive activity.  It also contains different kinds of enzymes that are not found in Fibrozym and Nattokinase 1500.  So, Neprinol is more concentrated and has a greater variety of enzymes than these other products.  Therefore, based on my experience since 2002 with men who are treating their Peyronie's bent penis, we have learned it is better to start treatment with the less intense and concentrated enzymes of Fibrozym and Nattokinase 1500 to get accustomed to the action of these enzymes; it is easier on the body and men have less diarrhea this way.   When you re-order the 1st or 2nd time you can then slowly introduce Neprinol into your treatment plan.

     "2.  Cost.  Because the bottle of Neprinol contains 300 capsules of more powerful and concentrated enzymes, as compared to 100 capsules in the other products, Neprinol costs more.  Therefore, after almost seven years experience working with men who are treating their Peyronies disease, we have found that men feel more comfortable keeping costs down when getting started.  The first order is the most expensive, and this is appreciated by men just starting who want to see how the suggested PDI plans work."

I will usually suggest to men that after being on your plan for a few weeks or few months, or whenever you are comfortable adding Neprinol to your plan, that you do so.  Many men will later use Neprinol as the primary source of systemic enzymes in their plan, but also keep a few Nattokinase 1500 and Fibrozym in their plans as secondary or minor sources of systemic enzymes. 

When I was actively treating my Peyronies I took all three products, but with a greater emphasis on the Neprinol.  I do not think you must necessarily do it this way for you to be successful; I did it just to cover my bases and to keep my tissue as saturated as possible with the enzymes.

Peyronie's disease is a tough and terrible thing to happen to a man.  It takes dedication and persistence to overcome it.   It is never easy to overcome, but always worthwhile.  

The biggest advantage in ordering your therapy products from PDI is that we provide a high level of service and background information specific to the problem of PD that you will not receive from anyone else.   Each product you order from PDI comes with all the information you will need to you it correctly to treat your Peyronie's disease. You cannot expect that kind of vital information from any other source.   TRH