How do I develop synergy to treat my Peyronies disease?

Been searching your site, have ordered Neprinol, but have not found the alternative product suggested for the synergy 'maybe' needed — besides Vitamin E, which I take.

Greetings,

Please read this page from the PDI website, "Synergy and Treatment of Peyronie's Disease."

In this discussion you will learn that synergy results from the combined use of several different therapies, but not any particular therapies.   For successful Peyronie's disease treatment the more therapy and wider variety of therapy products that are used, the deeper and more effective your synergy will be – the more the merrier.

Synergy is a natural reaction when groups of similar things are combined.   Let's take for example people.    If we combine a group of people who are slightly bad, when they get together they will tend to do things and behave in a way that is generally more bad than they would if they were not together.   In a similar way,  if we combine a group of people who are good, when they get together they will tend to do things and behave in a way that is generally better than they would if they were not together.  I suppose you can say that by combining similar things the natural tendency of those things is intensified. This is synergy. There is no limit to the number of things you can add for synergy to happen, and everything seems to be affected by it so you can use any Peyronie treatment you want to cause it to help you.

In the Alternative Medicine treatment of Peyronie's disease we  use different therapies that have been shown to be slightly effective as a Peyronie's therapy.  But when you combine them – the more the better – you get an increase of this ability to reverse  the Peyronies problem.

Further, since no one can tell which of the Peyronies therapies you need most and which you are lowest in, we approach treatment from a broad base that you supply all of those that could be helpful so that you are not missing any and this will also strengthen the effect of synergy on your problem.  Let me know if you have any more questions about the Alternative Medicine treatment of Peyronies disease. TRH

Is it best to take Neprinol on an empty stomach?

Hi Dr. Is it best to take Neprinol on an empty stomach ?

 

Greetings,

Yes, it is best to take Neprinol at least 90 minutes before or 90 minutes after you eat.

If you are only taking Neprinol as a Peyronies treatment you are likely making a mistake.   Neprinol works best when taken as the primary component of a larger aggressive treatment plan.

You are also making a mistake by buying your Neprinol from people who do not know about Peyronie's disease and cannot guide you and give you advice for care.  When you purchase Neprinol form PDI you will be given a great amount of information that will tell you how to use this product – and all the other products you will need to take  –  correctly.   Our prices cannot be beat and out PD help is second to none.   TRH

Have you any knowledge about serrapeptase or nattokinase for Peyronie’s treatment?

Hi, I just ordered your massage CD.

Have you any knowledge on the product serrapeptase or nattokinase?

They are in a category of systemic enzymes which are fibrolytic — fibrolytic enzymes break down fibrin and reduce or prevent scarring. Examples of these are serrapeptase and nattokinase. So, more precisely, could a fibrolytic enzyme like serrapeptase possibly reduce the fibrosis in the penis?

Best to you,

Michael

 

Greetings Michael,

Certainly.  Since 2002 PDI has advocated the use of the fibrinolytic enzymes, nattokinase and serrapeptase to treat Peyronies disease.  You may learn more about them here Enzymes (Neprinol, Nattokinase and Fibrozym) for Peyronie’s Treatment.   TRH

 

What is the dosage of therapy that will improve my Peyrnonie’s disease?

I am taking a combination of Neprinol, Vitamin C and Vitamin E. Can you advise me of a good number of each to be taken per day? I am currently taking 6 Neprinol per day, 3,000 mg of Vitamin C and 800IU of Vitamin E per day. Is this a safe amount that will effect Peyronies disease?

Greetings,

As I write repeatedly in these commentaries, there is no way to know ahead of time if any therapy plan is going to be effective for any particular person's Peyronie's condition or what dosage will work for you.  This is why it is essential each plan should be as varied and aggressive as possible, and that it is followed faithfully each day.  Because you will be able to monitor the size, shape, density and surface features of your scar before therapy begins and as it continues you will know whether your plan is working.  If it is working, you continue following your plan. If it is not working, you slowly increase the dosage of your plan until you begin to notice changes in the scar.

It is essential that you not just take your various supplements, but that you "work" your plan.  The PDI concept of determining the dosage of Alternative Medicine to treat Peyronie's disease is based on a simple system followed to prescribe drugs in medical practice. 

This is how your medical doctor fine-tunes the dosage of the drugs he/she gives you:   Your dosage is started based primarily on your age and body weight for that particular drug – everyone starts at about the same dose, but it will change based on response to the drug.  You take the drug as prescribed, you return in a week or two and your doctor asks you questions and examines you to see if your symptoms have changed.  If your symptoms have been reduced to your doctor's satisfaction, your dosage is kept the same.  If your symptoms are the same the dosage is either increased or you are given even more drugs.  You now taken an increased drug dosage as prescribed, you again return in a week or two and your reduction of symptoms is determined.  If your symptoms are now reduced your dosage is kept at this higher level.  If your symptoms are the still same the dosage is once more increased or you are given even more drugs.  This goes on until your doctor thinks your symptoms are under control.  This is how medicine is generally prescribed. 

You can use the same method to determine how many and which of your different therapies to use to change the size, shape, density and surface features of your Peyronies plaque and hence to reduce the curved penis that the scar causes.

As you take the dosage of the Alternative Medicine therapies you are using you monitor the size, shape, density and surface features of your Peyronie's plaque or scar, just as a doctor would.   If your scar shows improvement (smaller, softer, a different shape, more difficult to locate or you have signs of the scar "falling apart," you keep dosage the same.  If your scar is the same size and shape, just as hard and just as easy to locate, you slightly increase the dosage of what you are taking or you add new therapy to your plan.   You compare your scar every 10-14 days, looking for positive signs of scar reduction.  This pattern of increased therapy continues until you find that your scar has begun to improve.

You do not just start popping a predetermined number of pills each day hoping that you get better.  You monitor your scar for positive scar changes and you are fully aware what it will take to make it happen.  This is PDI method of Peyronie's disease treatment.  

The Neprinol, vitamin E and C dosage you are taking is very common, and might even be a little low in regards to Neprinol.  Please refer to the notes and detailed instructions you were given about taking Neprinol when you received your order from PDI.

If you have specific questions about altering your Peyronies treatment plan please contact me directly.   TRH

Would PDI penis stretching technique help a congentially curved penis?

I've had a genetically caused curved penis all my life, but as far as I know, i don't have Peyronies scaring. Would your your penis stretching technique help my condition?


Greetings,

Please see my prior response to a similar question at, Stretching a Congenital Curved Penis.

In the last several weeks I have heard from a few more men who also have moderately bent penis they were born with – congenital curvature of the penis.  All have found improvement,e specially those who use Neprinol as part of the plan of care.   TRH

Can I take all my Neprinol capsules at one time?

I am taking 6 Neprinol capsules per day, along with 3,000 mg of vitamin C and 800 mg. of Vitamin E. Question: Can I take all Neprinol capsules at one time? I have been taking 3 in the morning and 3 in the afternoon on an empty stomach.

 

Greetings,

There is nothing basically wrong with taking six Neprinol at a time; many people do this without a problem.  The question is whether you, in particular, can or should be taking that many at a time.   For some people taking six Neprinol daily is excessive, while others can do it easily.  Most men who make progress eliminating and controlling their PD scars take around 10-16 Neprinol per day always with a wide variety of other internal and external therapies.   But as far as Neprinol is concerned, the real question is if this is a good dose that you can tolerate while you attempt to eliminate your Peyronie’s plaque.   I suggest that you attempt to slowly work your way up to six Neprinol at a time, since you are only taking three at a time now.  How this is done has been explained to you in the instructions you were given when you placed your order for your PD supplies.

When you ask if you can take all six Neprinol capsules at the same time, I must ask you why you want to do take your entire daily dose at one time.  If you want to do this merely for reasons for convenience (getting it over with and not having to bother with them for the rest of the day), then I must tell you I do not think it is a good idea.  The problem is that by cramming all your Neprinol into one small part of your day then you are leaving a larger part of the day when you have no Neprinol in your blood stream; you want to always keep some Neprinol working for you all day long by taking it often throughout the day.   The question is how much that should be.   For this reason if you are going to be taking only 6/day, then I suggest you continue to take them as you are now doing it.    TRH

Will a combination of Neprinol and vitamin E be effective for my Peyronie’s disease?

Do you think that a combination of Neprinol and vitamin E will be effective in helping my Peyronie's disease?

Greetings,

There is no way to tell ahead of time if any Peyronie's treatment plan will be effective.   No matter what plan you start with, it is always a guess to know at the start of care if it will help.   The eventual treatment plan a man uses to eliminate his PD is determined by its ability to influence the PD scar.  Each person has different needs, and this prevents one treatment idea from being the solution for everyone.    It is necessary to evaluate the effectiveness of any plan by looking for changes in the size, shape, density and surface features of your scars while you following your treatment.   You can start with any type of plan you believe might help you, but it is the response of the  scar tissue that guides and determines type of therapy that is used and at what dosage.

Your question tells me you have not spent much time on the PDI website.   You really should go over the PDI home page and follow the links you will find there.  If you are interested in recovering from your PD it is a great way to get an education how Alternative Medicine can be used to increase your ability to heal and repair the Peyronie's plaque that is causing your bent penis.

Using Neprinol and vitamin E is a small combination that is far too limited to reach into the problem of Peyronie's disease.  I have never heard of anyone who used this combination and got results.   As an example, if you look at the PDI small plan you will see there are seven different ingredients in that plan – and it is called small.   I am fully aware that many men can have financial problems that limit the amount of therapy they use, yet these same men also want a Peyronie's treatment plan that gets results.

You see, it is not really what I think about using Neprinol and vitamin E that is important.   All I can tell you is that no one has ever told me that taking only these two therapies has helped his PD.    Usually, the plan must be larger to be effective.   How large does your plan have to be?   I don't know.   You have to figure that out for yourself while you are working with your problem.  I suggest you start here reading this website of the Peyronie's Disease Institute to  learn how this is done.   TRH

Would Neprinol work on my Peyronie’s disease?

Hi,

I've had Peyronies now for roughly 10 years. I passed a kidney stone in my 30's and it jammed at the end of my urethra, I squeezed it ,and it passed. But for a month my penis killed me. It eventually shrunk to about 3 inches, from 7  1/4 inches . Ive tried everything. I went all natural. vitamin c, 1000mg , omega 3 1200mg, vitamin e 1000 mg, l-arginine, ginkgo biloba, saw palmetto 1000mg, and flax seed oil, 1000mg gotu kola.  All have helped get at least 6 inches in length back after 10 years.

My love life suffered at first, but we overcame things. I would like to get the other 1 1/4 inches back. Right at the tip, just behind, it curves up around 30 to 35 deg. I can feel the hard plaque still. It just won't soften up any more.

Would Neprinol work, or do you have any suggestions on how to finally rid my self of this man destroying dilemma?  I'm 45 now, I would like to keep going if you know what I mean.

Thanks.  Any suggestions would be a great help.

Greetings,

While I realize you have probably just discovered the Peyronie's Disease Institute website on the internet, my first suggestion is that you stop playing around using different herbs and supplements that have not been shown to be helpful for treating PD.

"Going natural" is not the key to successful Peyronie's treatment; you have to use the right products and use them in the right way.  It looks to me like you just started using anything that might have had some positive things written about it, and hoped it would help your problem.   You have not "used everything."   You have only scratched the surface.   You have approached your problem from the wrong direction and gotten lucky that some of the things you did  might have helped you.   Had you spent that same time, effort and money using the products from the PDI lineup for your Peyronie's treatment I believe you would have been far better off today.

I suggest you get on at least the PDI medium plan along with the PDI gentle Manual Penis Stretching CD video and use them faithfully for a few months.  It is important to use the exact therapies from PDI because not all brands of Alternative Medicine therapies are of the same quality or potency.   You cannot walk into the average vitamin store and expect to get good quality products that will do the job for you.  It is amazing and appalling that many vitamin shops sell such low quality items.

Your question about Neprinol shows that you do not understand how to use Neprinol and that you are again approaching your therapy from the wrong direction.   You need to spend more time reading what is on the PDI website to learn how to go about successful Peyronies treatment. 

When you order from PDI you will receive specific instructions how to use everything that you order for the best possible treatment of Peyronies disease.   Let me know if you have specific questions about helping your problem.   Good luck to you.   TRH   

Stretching a congenital penis curvature

Hi Doc,

I posted a previous question about my congenital curvature downward and you recommended that I purchase the Manual Stretching video, I did, and have been doing the stretches every day and sometimes i have a day or two break which is rare, but ive been pretty persistent.

Do you also suggest I be more frequent? is frequency necessary? Also, I really want to know EVERYTHING possible i can do to lessen my downward curve, stretching or anything else you have in mind. I'd love to start having a more aggressive approach to see some results. Ive been taking neprinol for the past 2 months but ran out of supply, and came to the conclusion i don't' have peyronies so i don't need to take neprinol correct?

Please let me know of everything i can do to help me. '

Thanks so much.

 

Greetings,

As I mentioned in the reply to your earlier questions, all research done with the PDI Manual Penis Stretching technique was done with men who had PD and were using a variety of different PD therapy programs (vitamins E and C,  Neprinol, MSM, DMSO, etc.).  We have never researched the use of this method against a congenital penis curvature.   I mentioned that I have had men contact me who had a congenital curve and used this technique and got very good results.  That is about what I can tell you directly what I know about this subject. 

I tend to agree with you that Neprinol would likely no be of great use in your situation.  I suppose it is possible that it could help your effort, but I do not see a logical way this might happen, but at this time I just do not see it.

Since you ask about anything else I have in mind that might help you, I believe that the use of topical PMD DMSO with vitamin E and copper peptides does make more sense than Neprinol in your case.  This is conjecture on my part, but it does seem logical to me this should be helpful.  If you agree, then you might consider adding that to what you are currently doing.

Lastly, frequency and consistency of use of the penis stretching work is essential. The more often you apply this gentle stretching work the greater your odds for success.  This is probably the most important element of what you can do to help yourself, so please put in more time applying this gentle stretching.

Please let me know how you progress.  Since this is new territory for me, I would like to know more about what you are doing and how it works out for you.  TRH

What is the benefit of taking Neprinol rather than Nattokinase and Fibrozym?

Hello Dr. Herazy,

Thank you for the great site.

I am getting ready to place my first order with you and have a couple of questions:

1)  In your opinion what if any is the benefit of taking Neprinol over taking Nattokinase & Fibrozym. I understand your philosophy of overwhelming the problem but it seems like taking all 3 is overkill and from my limited understanding taking Nattokinase & Fibrozym sounds better than Neprinol?

2)  You do not mention the 15% Verapamil topical solution from PDLabs which seems to have had quite a few scientific studies done on it and the results seem to be very positive. Any thoughts on this would be greatly appreciated.

Thanks–I look forward to placing my order and getting started on a treatment plan.

Richard


Greetings Richard,

1)  The benefit of taking the single product, Neprinol, rather than the two products, Nattokinase and Fibrozym, is that the Neprinol is more concentrated and should result in taking fewer systemic enzyme pills per day while having a higher dosage intake.   In addition, Neprinol contains the additional enzymes of papain and bromelain.   The cost is higher for Neprinol, but considering the higher level of enzyme in the product, it is less expensive in the long term.   Yes, taking three different forms of a systemic enzyme might be more than is necessary, but for some men it does make a difference.  There is no way to anticipate how anyone will respond to their therapy plan, so I encourage everyone to experiment with different combinations of therapy products to determine how their scars will respond as you go through different combinations of products.

2)  Most every medical treatment for PD is the same – one or two positive studies and a larger list of negative studies about it.  The same with topical verapamil from PDLabs of Texas. The different studies mentioned by PDLabs of Texas are intriguing, but are contradicted by other similar studies of topical verapamil.  When i first developed PD in late 2001 or early 2002 and found the PDLabs website on the internet and read those studies I also was impressed with their conclusions.  for this reason I used their topical verapamil product for about six months, during which time my PD worsened considerably and I developed overwhelming side-effects that caused me to stop using the product.  At that time I realized I would have to look outside traditional medical treatment for helping my PD and I began to intensely investigate Alternative Medicine options; eventually I came upon the concept and and treatment protocol that developed into the Peyronie's Disease Institute.   Over the years I have discovered more controversy about their findings – but this is typical of any kind of treatment for PD.  It seems PD is always tangled in controversy and exceptions.   TRH