Tag Archives: Potaba

Not sure what to do next for Peyronie’s treatment

Posted on by Dr.Herazy

I have Peyronie’s disease for over 3 years.  Lately, the curvature is 45 degree and bending rapidly. It’s preventing me from concentrating and keeping a firm erection. This condition is starting to affect emotionally.  I avoid having sex.  I’m 52 years old and married for 25 years.

I had taken Potaba pills and did not work. For the past two weeks I have been taken Vitamin E. Not sure what to do next.

Looking forward to hear from you.

Your help is greatly appreciated.    Thank you.

E. Garcia

 

Greetings E. Garcia,

vitamin E by itself is not very effective as a Peyronie’s disease treatment, but then again there is nothing that when taken by itself will be effective.   To get truly good results with your vitamin E you must combine it with other therapy products to support and increase your body’s ability to remove the PD plaque material.

POTABA is not a well tolerated drug and it is not especially effective against Peyronies.  POTABA is a modification of PABA, a member of the B vitamin family, that is made into a drug by adding a potassium molecule onto the vitamin.   This was originally done because PABA received good research results as a Peyronies treatment, but the drug industry would prefer to sell drugs and not low-price and ow-profit vitamins.    So they created the drug POTABA that irritates the dickens out of the digestive track so much that few men can take the drug very long, and it does not work as well as PABA anyway.   For this reason we continue to suggest the use of PABA in Peyronie’s treatment plans.   

Please go to the PDI website and click on the link Start Peyronie’s treatment.    This is a good starting point to begin to put a plan of action together for your recovery.  Keep in mind that an important element of a good treatment strategy is to do a variety of Peyronies disease exercises along with using vitamins, minerals, enzymes and herbs to support your natural recovery.

 

Please let me know if you have any specific questions.   TRH 

What can PDI do for my 20 year old Peyronie’s disease?

Posted on by Dr.Herazy

hi, what can your method do for me and my 20 year old pd that started because of a sex accident?  bill


Greetings Bill,

Thanks for the question.

Since you have given me no details of your problem, I can only answer with generalities. The longest standing PD case with which I have been involved was a fellow who had it for 12 years. You see, most of the men I work with are usually in the 18 month to 3 year time range with their Peyronie's disease.  I think this is so because the average person who has dealt with PD for several years tends to just give up on himself and his situation, and assumes there is nothing out there for him.  The MDs eventually convince them to stop trying to get help because they do not have any drug for Peyronies treatment, and that is a shame.

Folks like you usually are not looking for help and answers – unfortunately.  But in the early phase of PD, a guy will really burn up the Internet wires looking for answers to his unsettling predicament. Having explained all that, it is my opinion that based on the favorable changes in the 12 year PD problem I worked with, and several others in the 3-8 year range I have worked with, your 20 year old problem stands as much a chance to improve as these others.

A long time ago I learned to never doubt the ability of the body to heal.

Many men, and myself, were able to get back all lost dimensions and eliminate any detectible scar formation, so I know it can be done. I assume you have just started to look at the large PDI website. Bear in mind what we propose is really different in the past in two important ways:
1. Synergy – grouping several therapies together at the same time.  If you are like most men who go the medical route, you probably used synthetic vitamin E for a short while and then did some POTABA or verapamil drug use later.  PDI approach is different because we advocate a combined treatment approach with many Alternative medicine therapies.
2. Quality and quantity of Alternative Medicine – most men do not appreciate the need to hit these two factors fairly hard. I can guide you in this respect to perhaps a better conclusion than you had in the past. In addition to a few vitamins, we also propose several other concurrent therapies for your PD that you have not used. These are very important to achieve the desired end result. The more you do, the stronger your synergy, the greater your odds for some success.  If you want to broaden your thinking about Peyronie's treatment with natural methods see natural Peyronie's treatment.

If you want some help to do this right, and I assume you do, send some specific questions about treatment.  PDI has a different website from anything else you will find anywhere because we have a reasonably optimistic attitude and track record with this problem, and because we actually know and care about men who have this lousy problem. I am retired now from active practice, and since overcoming and curing my own Peyronie's disease, I have pretty much devoted myself to this cause in appreciation and gratitude for the gift that was given to me.

When you are ready to do something good to help yourself, let me know.   TRH

What can I expect from POTABA in my Peyronie’s treatment?

Posted on by Dr.Herazy

I  WANT TO KNOW ABOUT THE PEYRONIE’S TREATMENT I HAVE BEEN PRESCRIBED.  I HAVE JUST SEEN A UROLOGIST WHO DIAGNOSED ME WITH PEYRONIE’S DISEASE. HE HAS PUT ME ON 400IU OF VITAMIN E THREE TIMES A DAY AND 12 GR. OF POTABA PER DAY.   IS THIS A GOOD COURSE OF TREATMENT?  WHAT CAN I EXPECT FOR A SUCCESS RATE?

THANK YOU

BOB

Greetings Bob,

In my opinion you should do a bit of online readying about POTABA. I think you will find a lot of controversy and reports of non-effectiveness about it.  From my experience there are fewer and fewer MDs using POTABA in the last few years because of high cost, limited results, and poor compliance because most men find they cannot tolerate the severe abdominal pain it causes even with the initial usage.  I am surprised your urologist did not mention this to you; I am sure he knows all about it. 

Did you ask the urologist what kind of success rate he has with this prescription?  Did you ask the urologist about what response and reactions you should expect while you are taking POTABA? I would be interested to know his response.

POTABA is one of the limited number of drugs available for prescription by an MD in the treatment of PD, although there are many MDs who do not prescribe POTABA  because they find the trouble their patients encounter while taking it does not justify the limited potential benefit.

Now, POTABA is nothing more than a simple B vitamin – PABA – that has a molecule of potassium added to it, or to say it another way, POTABA is a potassium salt of PABA.

PABA has been shown years ago in medical research to be successful in treatment of PD, but the medical profession likes to use drugs (POTABA) whenever it can, and refuses to use something as simple as a B-vitamin.  POTABA causes a host of gastric symptoms, for which reason few men complete their course of therapy with it.   PABA works just as well, and has no side-effects.  However, neither PABA or POTABA produce results as good as PABA when combined in a more aggressive therapy program as you see presented on the PDI website.

You should know this is a rather limited course of therapy.  No one can predict whether it will help you or not, you must follow if for a while to determine if it will improve the size, shape, density or surface quality of your Peyronie’s plaque.   You would be wise to get the book I wrote, “Peyronie’s Disease Handbook,” about dealing with Peyronie’s disease on a daily basis to improve your chances for recovery.

The Peyronie’s Disease Institute has offered PABA to its visitors since 2002 for treatment of Peyronie’s disease without a single report of inability to use it because of gastric problems.

Why is it you do not offer any guarantee?

Posted on by Dr.Herazy

I have Peyronies disease now since I discovered I was getting a bent penis in November last year. My doctor prescribed potaba but it has done nothing in almost 4 months of treatment and in fact it seems to have got worse. I also am taking vitamin e and c that I got from the health food store but again it has done nothing.

My penis is bending sideways and upwards and seems to have an indent underneath at the head of the penis. All very upsetting psychologically also.

I found your web site and read your treatment options.  Why is it you do not offer any guarantee of your treatment?

Alex

Greetings Alex,

You must be using the correct vitamin products in the correct way to gain a positive response.  Just because you got your vitamin E and C from the health food store does not mean that they were good products.  It is estimated that over 25% of vitamin and herbal supplements sold on the open market do not contain what the label says. Many have inferior grade synthetic products.  Not all vitamin E products are created equal, and many are not what they say they are. If you are using an inferior product (without knowing it) you will not get good results. That is why I strongly encourage any one who wants to treat his Peyronie's disease with Alternative Medicine products to get them from PDI for a few reasons:

  • High product quality – these are the same products I used when I successfully treated my own PD problem
  • Great prices and discounts
  • Fresh products since PDI is the largest buyer of several of the products we sell
  • Proven effectiveness – results since 2002
  • Consultation about your treatment – I cannot discuss your treatment, or answer your questions, if I do not have experience or confidence in outside therapy products

Using only vitamin E and vitamin C is a very limited and poorly designed Peyronie's treatment idea.  I have never heard of anyone getting results with that kind of plan.   These two vitamins are great products and serve an important part in many of the plans we use, but they cannot do the total job to eliminate the PD scar. I would never suggest to anyone to try using only only vitamin E and vitamin C as you did.   

Most men who go about using their own ideas and get their own products like you are doing make very little progress with their Peyronie's disease problem.  This is a complicated and difficult problem.  You will have to admit you are guessing at a lot of what you have done and your are experimenting on yourself at a time when you should be actively treating yourself.  On the PDI website we provide a tremendous amount of free services and information like this constantly updated Q&A section and a Peyronie's treatment forum, along with private emails to men from around the world. We make these resources available to men to support their effort to correct their own PD.  If you work with the PDI system of treatment I can assist you when ideas, information and suggestions based on my experience; you will not be working alone.

You ask about a guarantee.

Who do you know in the healthcare field who offers a guarantee for any procedure or therapy? Aspirins do not come with a guarantee.  Jock itch spray does not come with a guarantee.  Toothpaste does not come with a guarantee.  Foot supports do not come with a guarantee.  Surgery does not come with a guarantee.  No one in healthcare offers a guarantee because of the complexity and difficulty of what we are attempting to do.  Everything in health care is completely unpredictable.   When you go to your dentist and he puts some Novocain in your gum, during your dental procedure he will ask you frequently if your mouth is still numb, right?  He has to ask you if your mouth is numb because he cannot guarantee the Novocain will work for you, or if he got enough in your tissue, or if he put it in the right location, or if it is not wearing off sooner than it should.  Nothing in health care can be guaranteed. 

Only people who are trying to fool you offer a guarantee for their unscrupulous products.  I see many international companies ( like in Pakistan, India, Romania) who try to sell secret herbal products and guarantee results in 30-60 days.  I hear frequently from men who bought those pills, got no results, and got no response from those companies when they tried to get their guaranteed refund.  

Be very suspicious when you see some treatment offered with a guarantee – especially for Peyronie's disease.

If you are interested in trying to help your body heal the Peyronie's scars, please let me know.   TRH 

Potaba and Peyronie’s Disease Treatment

Posted on by Dr.Herazy

Potaba for Peyronie's treatment based on PABA, a vitamin

PABA, or para-aminobenzoic acid, with a formula of H2NC6H4CO2H, is a white crystalline substance that is slightly water soluble.  POTABA, used to treat Peyronie's disease, is simply PABA with a molecule of potassium added to it.

PABA has been referred to as Vitamin Bx because it is an intermediate step in the bacterial manufacturing of folate or folic acid in the intestinal tract.  Some bacteria in the human intestinal tract, such as E. coli, require PABA for proper metabolism. Humans require folate since we lack the enzymes to convert PABA to folate, hence it is made available via the bacterial flora.  Sulfonamide drugs are similar to PABA in their chemical structure, and their antibacterial activity is due to their ability to interfere with the conversion of PABA to folate by the enzyme dihydropteroate synthetase.  In this way bacterial growth is restricted through folate deficiency without effect on human cells.

Medical use of Potaba (potassium para-aminobenzoate)

Potaba inhibits abnormal fibroblast proliferation, thus it can reduce formation of scar material early after injury.  It is speculated that this POTABA anti-inflammatory activity is dependent on initial biotransformation that starts with granulocytes that are stimulated through the initial injury.  It also inhibits abnormal fibroblast proliferation, acid mucopolysaccharide and glycosaminoglycan secretion that occur during the normal inflammatory process.

POTABA has been used to treat a variety of conditions characterized by chronic inflammation and fibrosis; this list includes scleroderma, dermatomyositis, morphea, pulmonary fibrosis and Peyronie's disease.

A POTABA research study was conducted by Carson who retrospectively reviewed 32 patients who were treated with 4,000 Mg of Potaba three times daily, for at least three months and later were followed for an average of 14.4 months.   Carson reported reduction of penile pain in 44% of those studied,  plaque or scar size reduction in 56%, and improvement of penile angulation in 58%. Complete reversal of penile distortion and angulation occurred in 26% of those studied. The average interval to improvement was 4.2 months, and younger patients with a shorter duration of disease were more likely to respond to therapy.  Even thought Carson’s study did not have controls, it suggests a possible role for POTABA in the medical therapy of Peyronie's disease.

Unfortunately, the results of Carson’s retrospective and uncontrolled research were not reported as an intent-to-treat study.  Further, the number of research subjects who started therapy but stopped because of severe abdominal symptoms prior to three months has never been disclosed.

Because of the expense of POTABA, the need to take POTABA three or more times daily, and frequent occurrence of severe gastrointestinal side-effects (burning pain, abdominal cramping, and bowel irritability0, make it very difficult for the average man with Peyronie’s disease to follow the treatment guidelines for even a short time.  Yet in order to be effective, the length of POTABA therapy is variable, but sometimes lasting 12-24 months of active care.

Medical use of PABA

When a single potassium molecule is added to PABA, it results in what is called a potassium salt; this combination of potassium and PABA is called POTABA.  It is used as a drug against fibrotic skin disorders, and as such it can be used in Peyronie's disease treatment.  PABA is also occasionally used to treat Irritable bowel syndrome to and related gastrointestinal symptoms, and in nutritional epidemiological studies to assess the completeness of 24-hour urine collection for the determination of urinary sodium, potassium, or nitrogen levels.

Despite the absence of any recognized syndromes of PABA deficiency in humans, many benefits are claimed for PABA as a nutritional supplement.  PABA is said to improve fatigue, irritability, depression, weeping eczema (moist eczema), scleroderma (premature hardening of skin), a patchy pigment loss in skin called vitiligo, and premature gray hair.

Peyronie’s disease:  POTABA or PABA?

The first Peyronie’s treatment work involved PABA, the vitamin.  When this was shown to be successful, work was then done to show that POTABA, the drug, could be more successful.  The interest is working with POTABA – the drug – was greater than with PABA – the vitamin – because the drug is more profitable and is easier to control use and distribution through the medical profession.

The reason PDI promotes the use of PABA for Peyronie’s disease treatment is because it has almost no side effects, is much less expensive to use, does not require a prescription and it combines well with other Alternative Medicine therapies.

For more information about the many ways to use Alternative Medicine to promote tissue repair and reversal of penile curvature, go to Peyronie’s Disease Institute.