What is the maximum "safe" daily dosage of Vitamin E for treatment of Peyronie's disease?

Posted on March 11, 2013July 21, 2015 by Dr.Herazy

What is the maximum “safe” daily dosage of Vitamin E (for example, Unique E) in IU that is recommended for treatment of Peyronie's disease. I have read that daily doses in excess of 1500 IU of d-alpha tocopherol can be potentially toxic. I am planning on taking Vitamin E, with Nattokinase 200mg 2x/day, and PABA 1000mg 3x/day. Any comments on this regimen are appreciated.

Greetings,

Please search this website for many articles I have written about safety of taking vitamin E within a Peyronie's disease treatment plan. For example: Peyronie's disease treatment and vitamin E and Peyronie's disease vitamin E therapy.

To answer your question directly, I usually recommend that a man takes 800-1200IU of Unique E daily in a Peyronies plan.

Concerning the brief plan that you have outlined, above, I suggest that you consider adding some external therapies to this plan (DMSO with related copper peptides and vitamin E as topical applications, gentle manual penis stretching, ultrasound, etc.). Your plan as you describe it is not fully developed. I suggest that you look at the small, medium or large PDI plans to get an idea of what a well rounded plan looks like.

Question about vitamin E

Posted on January 29, 2013July 21, 2015 by Dr.Herazy

Hi, I live in Estonia and I have pretty much surfed all the internet and cant seem to find any other Vitamin E supplements other than alpha tocopherol in my country. Right now I'm taking 300 IUs of alpha tocopherol daily, what would you suggest?

Thanks

Greetings,

professional writing

The vitamin E product we make available on the website of the Peyronie's Disease Institute contains all four factions of vitamin E: the alpha, beta, delta and gamma tocopherol members of that family. Please find it at Unique-E vitamin E. TRH

Does Unique-E oil have the tocotrienol portion of the vitamin E family in it?

Posted on October 29, 2012March 18, 2013 by Dr.Herazy

Hello Dr Herazy. My peyronies is very mild it was done in a sex accident around 7 months ago. My penis is still straight when erect and hasn't really changed. I just noticed a little more bend in my penis when I went to urinate in the morning. My condition is stable and isn't really changing. My urologist said it was a traumatic form of peyronies. There is no real scaring but noticed when I did it a small line on the side of my penis more noticeable when erect. I was thinking of using your Unique vitamin E oil. Does it have the tocotrienol parts of vitamin E in it? Thanks for reading my question.

Greetings,

Yes, Unique-E oil has both all four members of the tocotrienol part of the vitamin E family, as well as all four members of the tocopherol part of the vitamin E family. I trust you need to know that in addition to using the topical vitamin E you should use PMD DMSO after the vitamin E is applied to the area so that the vitamin E can be taken deeply into the involved tissue.

Further, you should not assume that your Peyronie's disease will stay the way it is now. Peyronie's disease is not a static problem; it changes over time, sometimes slowly and sometimes rapidly, but it seldom stays the same for very long. Most people take the position that it is far better to use Alternative Medicine to treat the Peyronie's problem while it is still small and manageable to keep it that way. TRH

Can I get relief from fibrosis of the corpus spongiosum with Super CP Serum?

Posted on September 26, 2012December 18, 2013 by Dr.Herazy

I've been diagnosed with fibrosis of the Corpus spongiosum. Have you heard of any relief of this with the topical Super CP Serum and/or Vitamin E spray? Any other possibilities?

Thanks,

Spencer G.

Greetings Spenser,

The corpus spongiosum is cylindrical mass of tissue in the penis through which the urethra passes, located in the bottom half of the penis below the two corpora cavernosae. There are irregular cases of Peyronie's disease that start as fibrosis in the corpus spongiosum and later extend toward and into the tunica albuginea layer that surrounds the corpora cavernosae. At this point the fibrosis becomes Peyronie's disease.

When you ask about using topical Super CP Serum and Vitamin E oil you are forgetting about the most important component of the topical applications, and that is PMD DMSO. Using Super CP Serum and Vitamin E oil by themselves is fairly useless since they lack the ability to penetrate the tissue to get down to where the fibrosis problem is located. So please be sure to include DMSO in this topical treatment, always applying the DMSO last. When you order from PDI you will be instructed how to use all of these products for greatest effectiveness.

What do you think is the best route for Peyronie's treatment?

Posted on August 17, 2012July 21, 2015 by Dr.Herazy

I am a 39 year old male that developed peyronie's about 1 year ago. Much of the curvature has gone away, but my erection still bends slightly down (compared to having a natural upward curve previously), and it has a dimple on the underside of the shaft. Most of the pain has gone away. At the recommendation of my urologist, I was taking oral Vitamin E of about 400 IU daily, and added Wobezym (6 pills daily), Serrapeptase (120,000 IU/2 daily), and bromelain (1000mg daily of 2,000 GDU/g).

I was considering ordering the medium plan along with the stretching DVD. Do you think this would be the best route to go? How long do you think it would take to see results?

Thanks.

Tony

Greetings Tony,

Judging your progress simply by noting good or bad changes in the penis curvature is not a good strategy. Naturally it is the bent penis that gets your attention and it is what you most want to see improved, but it is a poor way to evaluate what is going on with the Peyronie's disease treatment you are doing.

The fact is that the curved penis is not the primary problem of Peyronie's disease; the primary problem of Peyronie's disease is the internal scar or Peyronie's plaque that causes the penile distortion. The size, shape, density and surface features of the internal Peyronie's plaque this is what you need to measure and evaluate to determine if your effort is being truly successful or not.

Another fact is that your Peyronie's plaque can be worsening and your curved penis can become straighter at the same time this is happening. This happens when the growing PD scar tissue balances out the internal stresses and tissue pulling that takes place because of scar material. This is not a good thing. I f you have a large and complex interplay of PD scar material that is so arranged that your penis is straight, is this really desirable? Is it a good thing? If you say, “What do I care if the scars are getting worse? Just as long as the curve is getting better and I can continue to have sex.” The answer to that attitude is to understand that Peyronie's disease is not a static problem and over time it will worsen. You might eventually have the currently balanced scars become imbalanced and they can begin to pull the penis in a weird and abnormal way resulting in a worse curve than you had at the beginning of your problem.

Of course, I have no way to know the condition of your internal scar tissue. But then again, neither do you unless you understand this concept and are paying attention to what is really important. Your internal scar material could be totally reversed, it is possible, but you will never know and will remain at a distinct disadvantage for as long as you ignore what is going on inside.

Only you will know the best treatment route to take by noting the response of your scar in terms of changes of the size, shape, density and surface features of your internal Peyronie's plaque. The medium plan is a good one to work with. Take it as you are given suggestions when you receive your order and every 7-10 days evaluate your shaft for changes in the scar size, shape, density and surface features. Increase the dosage of your plan until you see definite and clear reduction of the size, shape, density and surface features of the plaque material. This is the very best way to know you are following the best plan of action for your recovery.

When a man follows a very aggressive Peyronies plan and does so faithfully, and finally reaches the correct dosage by slow incremental increase of dosage while evaluating the size, shape, density and surface features of his fibrous Peyronie's plaque, he can expect to see changes as quickly as 7-10 days after he has reached his correct dosage level. Notice, I did not say his PD would be gone, just that his scar would begin to be reabsorbed and start to get smaller as determined by these various measures. After that point it is usually 2-6 months of care to have all the tissue changes occur that will take place.

By the way, you might be getting better results with Neprinol. I also recommend that a good treatment strategy includes a variety of Peyronies disease exercises along with using vitamins, minerals, enzymes and herbs to support your natural recovery. TRH

How should I improve my success of Peyronies treatment using vitamin E?

Posted on August 2, 2012March 18, 2013 by Dr.Herazy

Sir i am 28 years old and i have bp from last 10 years taking olmat am (atagonist +amophline) tab sir my penis is bend towards left and upwards also for curing this i took vitamin e 400 capsule for 1 month yes results were OK means when i take my penis becomes straight and slight improvement as well but when i stopped taking vitamin e it started bending again for how long should i take vitamin e 400 and will it increase bp please guide sir as i will get married within 6 months please please please please

Greetings,

From the limited information you provide I do not have a good idea how you should proceed since I do not know anything about the kind of vitamin E you used. So I cannot comment on that element of what you have done to receive limited and temporary success.

However, based on my 10 years of experience treating Peyronie’s disease I suggest that you expand and deepen your plan to include more therapy than using a solo therapy of just vitamin E. My suggestion is to investigate how to improve your results by increasing your Peyronies treatment after reading how to start Peyronie’s treatment on the PDI website and using any of the plans you see available that make sense to you.

If you a specific question about treatment of Peyronie’s disease I would be pleased to assist you. TRH

How do I find the Peyronie’s scar?

Posted on August 1, 2012March 18, 2013 by Dr.Herazy

I was diagnosed with peyronies about 10 years ago. I had the classic lump and my penis had a bend to it. It isnt super bad but enough that I want it gone as much as possible. I took potaba and vitamin E for several months with no real progress. I cannot feel any scars or lumps at this time but it seems that my curve may be worsening all of the sudden. I do not have pain and can have intercourse but would really like to have as close to a normal penis as possible. Is there a way to treat my condition after so many years? How do I find the Peyronie's scar and what would be the best action to take on an extremely tight budget? I am now 41 years old and in good health other then some problems with my discs in my upper back.

Thank you so much,

Phil

Greetings Phil,

POTABA and vitamin E do not make much of impact on Peyronie's disease; what you were given was a desperation prescription just to give you something to do and get you out of the office.

It is not at all uncommon for an older case of Peyronie's disease to continue to deteriorate and develop an increased penis curvature. I have worked over the years with many men whose PD is in the 5-15 year range and they are still able to make improvement based on the concept that the Peyronie's plaque is still capable of change – for bad and for good.

Order "Peyronie's Disease Handbook" to learn how to find and define the PD scar since it is essential that you know all the physical features of it since you will use that information to determine how to manage your treatment program.

On a limited budget I would suggest starting with the small plan and working it aggressively against frequently monitoring your condition for making changes in the size, shape, density and surface features of your scars. TRH

Now that my Peyronie's disease is gone should I continue taking the supplements?

Posted on July 30, 2012July 21, 2015 by Dr.Herazy

I have had Peyronie's for approximately two years. I had about a 45 degree bend upwards and about a a 15-20 degree bend to the right. I noticed that I had a large scar along the top of the shaft about 2″ and a small nodule about 1/4 inch in diameter on the right side. I obtained your gentle manual penis stretching video and started with the exercises and took PABA, Vitamin E, Nattokinase as you suggested in the instructions PDI provides. I continued with this stretching exercise and the vitamins and enzymes and have now straightened out the shaft. I do not feel any more scar tissue. I was wondering if I am going to have to continue on with the PABA? I will continue to take the other natural vitamins and supplements as I was taking before i developed the Peyronie's, but I did not ever before take PABA so i wonder if I should continue with that. Thanks for your help.

Greetings,

First of all, congratulations on your successful treatment of Peyronie's disease. Many people doubt that they can do what you did. I get this kind of report from people around the world several times a week telling me that they have recovered from their terrible Peyronie's problem by following the simple directions and ideas found on the PDI website. Good for you.

the kidney disease solution

I doubt you will have to continue with the PABA or continue doing the gentle manual penis stretching technique now that your Peyronie's plaque is gone. Since 2002 I have been consulting with men about Peyronie's disease and in that time we have had some really great results. In all these years I have never had anyone come back to me a year or two or five years later to report that their PD has come back when they stopped taking the PDI Peyronies treatment plan they used to recover from their problem.

However, I would say that half of the men who get over their Peyronie's disease say they will continue with certain parts of it because they believe they get general health benefits from certain products (Neprinol, nattokinase, vitamin E, acetyl-L-carnitine, etc.) I have recovered from my own Peyronie's disease now for about ten years and still take Neprinol, Omega T, and vitamin E because I am convinced of their broad health benefits.

Again congratulations on your great Peyronie's treatment story. TRH

Should I use Neprinol as part of my Peyronie’s disease treatment?

Posted on June 5, 2012March 18, 2013 by Dr.Herazy

Dear Dr. Herazy:

I hope this message finds you and yours in good health.

It has been only three months that I “found” the PDI website after being suffering Peyronie’s disease for more than four years. I was diagnosed back in 2008 approximately when I went for pain on erections (reflected mostly on the front of the penis) to the current curvature of approximately 25 degrees upwards bending a bit to the right as well.

Due to the initial treatment in my country (Cuba) I got initially Vitamin E and then even direct injections on the plaque of Interferon and sessions of laser. None stopped the bending process after pain with erection disappeared. Then I stopped using Vitamin E, suspended laser and the injections and changed to an urologist that has been working on using natural pills made from bee’s propoleo. I have been taking these pills for more than two years before going to bed (and at least three hours after my last meal). This Dr. also used as a method the measurement of the curvature and sporadic ultra-sounds to keep track of the degrees of the curvature. I must say that in more than two years the curvature seems to keep being of the same degree (not healing but not bending either). Unfortunately for me and others this Dr. emigrated. He was substituted by another urologist who seems to have more faith in continuous ultra-sounds to compare the process of growth of the plaque. I skipped going to consultation like a year ago. It must be pessimism or lack of faith that I will solve this disease.

I have gone through serious stress in my own marriage and I feel somehow ashamed that I would not be able to find a woman that will cope with this disease in my country if I decide to divorce my wife. I have had all the reasons to divorce my wife but I feel stuck with her. You know, being from a Latino country and culture machismo is a big thing. I am 52 BTW.

Since I found about PDI I designed my own plan which is currently as follows:
1- I am taking daily at breakfasts:
a- PABA (500 Mg)
b- Acetyl L-Carnitine (500 mg)
c- Glucosamine with MSM (500 mg)

2- I also take daily around 3 PM: MSM (500 mg)

3- I take as well a pill daily 3 hours after dinner of Propoleo

I do not have enough resources but I am ready to pay for whatever even if I have to sell my belongings. So my question to you is what you would suggest someone in my stage of Peyronie’s disease to buy? I know I should buy your books (re: “Peyronie’s Disease and Sex and Peyronie’s Disease Handbook) but what else, please?

Should I use Neprinol? Should I go back to Vitamin E being added to everything I am using already?

Being in the Caribbean (and subject to a US Embargo) the only way I would have to get all I need will be through friends living in the States visiting my country twice a year. I will have to reveal my disease to one of them so to seek his help. I am ready to do whatever it takes.

Best regards,

M. C.
Havana, Cuba

Greetings M.C.,

So sorry to learn of the difficulty you are having in finding and using a good Peyronie’s disease treatment. You are to be commended for working so diligently to help yourself.

While I understand why you have been forced to try to duplicate a PDI-type treatment for Peyronie’s disease using substitute products since you cannot get them from PDI in the U.S., this is a great problem. It is very likely that the quality and subsequent quantity of actual useable nutrients that are available to your body are not sufficient to help your tissue heal and eliminate the Peyronie’s plaque. Just because the label might say there is 500 mg. of PABA or acetyl-L-carnitine in a product does not mean it is of sufficient quality to help your tissue heal, or that it is even present in the pill. This is why I insist that men who are serious about eliminating their PD will only use those products that I have had good success with against Peyronies. Correction of this problem is too important to take a chance that you could be using questionable or poor quality therapy.

As a general comment concerning what you are currently doing, a basic problem is that you are only using internal-type therapy items and no external therapies such as DMSO,topical copper and vitamin E, manual stretching or non-penetrating acupuncture treatments.

Another general comment is that you are apparently taking those therapies you currently have available but you have not tested or compared during use against the size, shape, density or surface features of the PD scars to determine the correct dosage. In other words, you are swallowing a lot of pills hoping something good will happen to you. But that is not how the PDI process works. I want you to know the exactly correct dosage to make the best progress possible.

Yes, both books are a wealth of practical information; they will help you toward your recovery.

Neprinol is a great Peyronie’s therapy, but by itself I have not seen it be very effective; it must be combined with other therapies for maximum benefits to occur. Please refer to the PDI website for more information about this aspect of treatment.In addition, when you order Neprinol from PDI you will be given specific information about how to use it for maximum recovery benefit. See Peyronie’s disease treatment with Neprinol.

Using vitamin E requires that it is the right kind of vitamin E and it is of excellent quality. I cannot advise about using what you currently have been taking because I have no idea if it will be good enough to help you; it could be a waste of your time, effort and money.

Lastly, you are not the only person who we help receive PDI therapy products from visiting relatives. Please send me an email to alert me when you are ready to place your order and I will see to it that we get this done as economically and effectively as possible for you. Please keep me informed and I will do all I can to help you. TRH

Can you help me with my Peyronies treatment and my heavy nutritional intake?

Posted on May 4, 2012July 21, 2015 by Dr.Herazy

Dr. Herazy:

We spoke a couple of years ago when I was changing careers from being a long-time financial adviser to becoming a physician (either a holistic MD, Emergency Room Doctor, or possibly now a nutritionist or orthomolecular medicine practitioner). I am now in pre-med classes at age 60, and other than the Peyronie’s Disease and a small left-side inguinal hernia, in stellar health. In the past two years, my physical workouts stopped due to a rigorous study and work schedule, then the hernia appeared. Due to the cautionary advice of my trainer, I now work out carefully 3 times a week, have excellent labs, and do Qi Gong (ancient Chinese healing martial art) and Myofascial Release and other stretches every morning. I look and feel much younger than my age. The small, left side inguinal hernia appeared in November 2011 from working as an EMT on a transport ambulance, and I took a leave of absence in December 2011 pending surgery, which is currently pending with my employer’s workers compensation insurer. I was advised that it should be resolved by October. I currently take 71 different natural supplements daily in pill, tincture, liquid and powder form to the tune of 150 doses each day and have since 2006. This was carefully designed by a medical practitioner under an anti-aging and naturally detoxification protocol from the work of Dr. Gary Null, PhD.

According to my former urologist, whom I first consulted since he performed a vasectomy on me in 1994(?), the popping sound I heard during intercourse several years ago (2008 or 2009) was the beginning of the Peyronies issue, though for about seven years prior I had noticed a slight weakening of my erection. Now, my penis curves downward almost 90 degrees during engorgement, and it appears as if there is an invisible ring at the base of my penis constricting it. During intercourse there is no pain (there was some initial burning sensation inside my penis as I recall after the incident), and I am still able to have somewhat satisfactory intercourse, reaching ejaculation, with my female partner. My penis does become flaccid at times during intercourse and it certainly is not as pleasurable as before the incident. According to my former urologist’s caution, I keep in mind that intercourse could cause further damage so my partner and I are careful.

I want to return to having a healthy erection and intercourse experience, which I did throughout my entire sex life since late teenage-hood. I take 800 mg of pharmaceutical grade natural Vitamin E daily as part of my supplements protocol above. For reasons other than Peyronie’s, to move away from allopathic medicine, I changed doctors to a highly recommended holistic MD, board certified in many specialties, who just happened to have experience with a severe Peyronie’s patient (this was a plus though not my primary reason for choosing him). He had me take a highly concentrated form of pharmaceutical grade PABA (Potaba) because he said it would help eliminate scar tissue anywhere in my body. Only with a prescription I ordered it from a top pharmacy in Canada and over several months, built up to a course of 8 Grams (I believe) a day with little resulting correction, though the change was not scientifically measured. Before reordering a third time in August 2011, I let my doctor know that it did not resolve the issue, though it may have helped, and gave him your information. He then told me to follow through with you.

Before calling you a couple of years ago I read the book of the nutritionist with whom you treated. I contacted him several times but he did not respond. I then called you and you said your body of work went greatly beyond his, but with all of my occupation change and education activities, I am just now getting back to you for a plan of action.

How do I start on a definitive course of action to reverse this structural condition? I would be glad to share with you my entire supplement protocol so you may see what I am taking and how it may be supplemented.

With appreciation,

Peter A. Lindsley

Greetings Peter,

Good to hear from you again. I was wondering what you might be doing. Thank you for the interesting and detailed Peyronie’s disease history.

You are not the first man who reports to me that he is in exemplary physical condition, yet Peyronies develops after injury. The only way I can explain it is that someone who is in perfect health, following a perfect dietary and nutritional program, would still be subject to injury by falling down the stairs, hitting his thumb with a hammer, an automobile accident – or injury to the penis during intercourse. Being healthy and well nourished does not make you bullet-proof to trauma.

Many MDs approve of the PDI concept of treatment for this problem. It makes sense and it is based on documented research results. I find that when MDs develop Peyronie’s disease they eventually come to PDI for treatment since there is nothing for them in their own medical camp to use with confidence. I work with MDs for their personal recovery.

A pharmaceutical grade of PABA is not POTABA; they are two different things. PABA is considered a B vitamin. POTABA is PABA with a potassium molecule attached to it and is considered a drug, no longer a B vitamin. They are similar but not the same thing. The early Peyronie’s research work that was done with PABA got good clinical results, so naturally the MDs assumed that POTABA (the drug that they can control because it is a prescription item) would work better. POTABA causes many side effects and few men can take it long enough to complete the intense dosage of three months. You are far better off using PABA the way we recommend it.

Because of your high supplement intake I suggest that you contact me for a telephone consultation about treatment. For the most part I suggest you at least start by reading the information found at Start Peyronie’s Treatment. TRH